Results 71 to 80 of about 1,022,317 (308)

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Current Perspectives and Trend of Acupuncture in Breast Cancer-Related Symptoms: A Bibliometric Study

Journal of Pain Research, 2023
Hanzhi Wang,1,2,* Siying Qu,2,* Tianshu Zhou,3,* Qunqi Hu,2 Xiaoxuan Zhao,1 Qujia Yang,1,2 Hengyu Chi,2 Shiling Luo,1 Xinyue Li,4 Huanxiao Ke,1,2 Xiaofen He,5 Hongli Zhao1 1Department of Traditional Chinese Medicine (TCM) Gynecology, Hangzhou
Wang H, Qu S, Zhou T, Hu Q, Zhao X, Yang Q, Chi H, Luo S, Li X, Ke H, He X, Zhao H   +11 more
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Sustainable Approaches to Realize Carbon Neutrality in China: A Case Study of Zhejiang Province

, 2022
With the continuous development of industry, the massive emission of carbon dioxide (CO2) has become a global challenge that cannot be ignored due to its nature as the primary driver of global climate change and environmental crisis. Carbon neutrality is
Yifan Huang, Weiqi Fu, Yuexuan Shu, Jiwei Chen   +3 more
core   +1 more source

Integrating Genetics With Epidemiological Measurements Identifies Burden QTLs of Inflammatory Bowel Disease across 20 Countries

Advanced Science, EarlyView.
The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...
Chen Sun, Siyu Wei, Junxian Tao, Haiyan Chen, Chi Yan, Jiacheng Wang, Jing Xu, Lian Duan, Yuanbo Zhan, Yuping Zou, Ruilin Li, Linna Yuan, Wei She, Songlin Lu, Ning Wang, Qinduo Ren, Yan Guo, Yuan Xu, Chang Wang, Hongsheng Tian, Chen Zhang, Yu Dong, Guoping Tang, Zhenwei Shang, Yongshuai Jiang, Wenhua Lv, Mingming Zhang, Hongchao Lyu   +27 more
wiley   +1 more source

Epidemiology and spatiotemporal analysis of acute hemorrhagic conjunctivitis in Zhejiang province, China (2004–2023)

Frontiers in Public Health
BackgroundAcute hemorrhagic conjunctivitis (AHC) has become a significant public health issue in Zhejiang province. However, the analysis of epidemiological characteristics and spatio-temporal patterns of AHC in Zhejiang province has not been studied yet.
Wanwan Sun, Yijuan Chen, Shuwen Qin, Ziping Miao   +3 more
doaj   +1 more source

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

Advanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu, Minmin Mao, Beltzane Garcia Cirera, Hao Ye, Xiangzhong Chen, Josep Puigmartí‐Luis, Ni Qin, Salvador Pané   +7 more
wiley   +1 more source

On the Pilot Agriculture Insurance Program in Zhejiang Province [PDF]

, 2010
Zhejiang Province of China suffers heavy economic loss in agriculture due to frequent disastrous events. In 2006, the provincial and local governments in Zhejiang Province initiated a pilot agriculture insurance program with the touching-stones-to-cross ...
Fang, Weihua, Wei Lin, Yang Qiao, Weihua Fang, Li, Man, Qiao, Yang, Xingchun Zhong, Man Li, Zhong, Xingchun, Lin, Wei   +9 more
core   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Proteasome, a Promising Therapeutic Target for Multiple Diseases Beyond Cancer

Drug Design, Development and Therapy, 2020
Yu Cao,1,* Huajian Zhu,1,* Ruoyu He,2 Limin Kong,3 Jiaan Shao,1 Rangxiao Zhuang,2 Jianjun Xi,2 Jiankang Zhang1 1School of Medicine, Zhejiang University City College, Hangzhou, Zhejiang Province, 310015, People’s Republic of China; 2Department of ...
Cao Y, Zhu H, He R, Kong L, Shao J, Zhuang R, Xi J, Zhang J   +7 more
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