Results 101 to 110 of about 1,754,910 (336)
Nature Reviews Microbiology, 2018 The recent epidemic of Zika virus (ZIKV) in the Americas has revealed the devastating consequences of ZIKV infection, particularly in pregnant women. Congenital Zika syndrome, characterized by malformations and microcephaly in neonates as well as developmental challenges in children, highlights the need for the development of a safe and effective ...
Peter Abbink +4 more
openaire +2 more sources
Promising Prodiginins Biological Activities
Chemistry &Biodiversity, EarlyView.ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto +6 more
wiley +1 more source
Antibodies Elicited by an NS1-Based Vaccine Protect Mice against Zika Virus
mBio, 2019 Zika virus is a mosquito-borne flavivirus which can cause severe disease in humans, including microcephaly and other congenital malformations in newborns and Guillain-Barré syndrome in adults. There are currently no approved prophylactics or therapeutics
Mark J. Bailey +6 more
doaj +1 more source
Reviews of Science for Science Librarians: The Challenge of the Zika Virus: An Emerging Arbovirus Disease [PDF]
, 2016 First identified in Uganda in 1947, the Zika virus simmered quietly for sixty years, occasionally causing a mild dengue-like illness across parts of central Africa and equatorial Asia.
Delwiche, Frances A
core +2 more sources
Metabolic reprogramming by Zika virus provokes inflammation in human placenta
Nature Communications, 2020 The recent outbreak of Zika virus (ZIKV) was associated with birth defects and pregnancy loss when maternal infection occurs in early pregnancy, but specific mechanisms driving placental insufficiency and subsequent ZIKV-mediated pathogenesis remain ...
Qian Chen +8 more
semanticscholar +1 more source
Antibacterial and antiviral activity of a highly efficient electrospun r‐PET nanofiber
The Canadian Journal of Chemical Engineering, EarlyView.Abstract Since the COVID‐19 pandemic, the emergence of clean air has increased interest in developing antimicrobial air filters, targeting sterilization and public health concerns. Nanofibers are a promising approach due to their high efficiency in air filtration, while nanoparticles adhered to the fibre surfaces can improve safety due to the biocidal ...
Karine Machry +8 more
wiley +1 more source
New Pyridobenothiazolone Derivatives Display Nanomolar Pan‐Serotype Anti‐Dengue Virus Activity
ChemMedChem, EarlyView.A ligand‐based strategy is employed, starting from hit compound 2, to develop the C‐2 modified pyridobenzothiazolone 19 as a pan‐serotype nanomolar DENV‐1‐4 inhibitor. Investigations of the mechanism reveal the peculiar ability to abolish the infectivity of virions in a second infection.
Tommaso Felicetti +13 more
wiley +1 more source
Zika virus infection – a new epidemic threat
Pediatria i Medycyna Rodzinna, 2016 Zika virus, like dengue and yellow fever viruses, is an RNA virus of the Flaviviridae family. The virus is transmitted by Aedes mosquitoes. On February 1, 2016, the World Health Organization declared Zika virus a Public Health Emergency of International
Dominika Pomorska, Ernest Kuchar
doaj +1 more source
Capsid protein structure in Zika virus reveals the flavivirus assembly process
Nature Communications, 2020 Structures of flavivirus (dengue virus and Zika virus) particles are known to near-atomic resolution and show detailed structure and arrangement of their surface proteins (E and prM in immature virus or M in mature virus). By contrast, the arrangement of
T. Y. Tan +11 more
semanticscholar +1 more source
Differentiation enhances Zika virus infection of neuronal brain cells. [PDF]
, 2018 Zika virus (ZIKV) is an emerging, mosquito-borne pathogen associated with a widespread 2015-2016 epidemic in the Western Hemisphere and a proven cause of microcephaly and other fetal brain defects in infants born to infected mothers. ZIKV infections have
Bouquet, Jerome +6 more
core +3 more sources