Results 91 to 100 of about 69,146 (301)

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

Advanced Intelligent Discovery, EarlyView.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki, Bassam Bachour Junior, Marcelo Mulato, José Ilton de Oliveira Filho   +3 more
wiley   +1 more source

Nervous System Injury and Neuroimaging of Zika Virus Infection

Frontiers in Neurology, 2018
In 2016, World Health Organization announced Zika virus infection and its neurological sequalae are a public health emergency of global scope. Preliminary studies have confirmed a relationship between Zika virus infection and certain neurological ...
Shanshan Wu, Shanshan Wu, Yu Zeng, Alexander Lerner, Bo Gao, Meng Law   +5 more
doaj   +1 more source

A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis [PDF]

, 2017
The structural flexibility or 'breathing' of the envelope (E) protein of flaviviruses allows virions to sample an ensemble of conformations at equilibrium.
Diamond, Michael S, Dowd, Kimberly A, Goo, Leslie, Pierson, Theodore C, VanBlargan, Laura A   +4 more
core   +5 more sources

Development of a Novel Aedes aegypti Repellent: An Integrated Approach Combining In Silico and Bioassays

Chemistry &Biodiversity, EarlyView.
OBP1 plays an essential role in the behavior response of Aedes aegypti. The computational approaches employed herein suggest a compound with repellency activity in the ZINC database, which was confirmed by bioassays. ABSTRACT Aedes aegypti is the most important vector of arboviruses, which are responsible for 3.9 billion cases worldwide.
Moysés Fagundes de Araujo Neto, Jânio Rodrigo de Jesus Santos, Ana Luiza Pontes Silva de Oliveira, Antonio Wanderson Vieira Gois, Ingrid Bernardes Santana Martins, Vitor Barbanti Pereira Leite, Adriano Figueiredo Monte Alegre, Jairo Torres Magalhães Junior, Franco Henrique Andrade Leite   +8 more
wiley   +1 more source

Serological evidence of Zika virus infection in febrile patients at Greater Accra Regional Hospital, Accra Ghana

BMC Research Notes, 2019
Objective Increase in the evidence of global occurrence of Zika viral infection suggests that in Africa the circulation of the virus which causes 80% of asymptomatic infection could be undetected and/or overlooked.
Godson Aryee Ankrah, Joseph Humphrey Kofi Bonney, Esinam Eudosia Agbosu, Deborah Pratt, Theophilus Korku Adiku   +4 more
doaj   +1 more source

Is the United States Prepared for a Major Zika Virus Outbreak? [PDF]

, 2016
Zika virus has emerged as a global public health crisis with active transmission in the Americas and Caribbean. The World Health Organization (WHO) declared a Public Health Emergency of International Concern (PHEIC), and recently WHO reported there is a ...
Gostin, Lawrence O., Hodge, James G., Jr.   +1 more
core   +2 more sources

Dynamics and Regulation of Maternal–Fetal Interface Macrophages: From Immune Tolerance to Pregnancy Outcomes

iMetaMed, EarlyView.
The maternal–fetal interface demands tolerance alongside antimicrobial defense. Plastic macrophages orchestrate inflammation resolution, tissue remodeling, and angiogenesis in normal gestation; complications (miscarriage, preterm birth) feature polarization skewing and dysfunction.
Xinyue Wang, Haochen Yang, Yunzhao Xu, Jinling Chen   +3 more
wiley   +1 more source

Zika Virus Infection and Implications for Reproduction

Fertility & Reproduction, 2019
Zika virus infection during pregnancy can have devastating effects on the foetus leading to congenital Zika syndrome. It is relevant therefore for couples living in countries with endemic Zika virus to understand the strategies they can utilise to reduce
Michelle L. Giles, Stephen Cole
doaj   +1 more source

ZIKV Phylogenetic Characterization Reveals Evolutionary Diversity, Regional Dissemination, and Emergence of African Lineages in Brazil

Journal of Basic Microbiology, EarlyView.
ABSTRACT During the last epidemic in 2015–2016, Zika virus (ZIKV) gaining worldwide attention due to its association with neurological complications such as microcephaly and Guillain‐Barré syndrome. ZIKV can be transmitted through vector‐borne, sexual, maternal‐fetal, and blood transfusion transmission.
Thayane da Encarnação Sá‐Guimarães, Pedro Panzenhagen, Anita Ferreira do Valle, Carlos Adam Conte Junior, Mônica Ferreira Moreira   +4 more
wiley   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source