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In less than 2 years since entry into the Americas, we have witnessed the emergent spread of Zika virus into large subsets of immunologically naïve human populations and then encountered the devastating effects of microcephaly and brain anomalies that can arise from in utero infection with the virus.
James P. Nataro, Debbie-Ann Shirley
+12 more sources
Since its discovery in 1947 in Uganda, the Zika virus (ZIKV) remained in the shadows emerging in 2007 in Micronesia, where hundreds of dengue-like syndromes were reported. Then, in 2013-2014, it was rife in French Polynesia, where the first neurological effects were observed.
de Laval, Franck+5 more
openaire +4 more sources
Maternal Zika Virus Infection in the First Trimester and Fetal Stigmata in the Third Trimester
Zika is a flavivirus that is transmitted primarily by the bite of an infected Aedes mosquito. It can also be transmitted by blood transfusion, sexual contact, and from an infected mother to the unborn baby.
Divya Singh, Ladbans Kaur
doaj +1 more source
Zika virus infection during pregnancy can cause serious birth defects of the brain and eyes, including intracranial calcifications, cerebral or cortical atrophy, chorioretinal abnormalities, and optic nerve abnormalities (1,2).
Nicole M Roth+64 more
semanticscholar +1 more source
Calibration of a SEIR-SEI epidemic model to describe the Zika virus outbreak in Brazil [PDF]
Multiple instances of Zika virus epidemic have been reported around the world in the last two decades, turning the related illness into an international concern. In this context the use of mathematical models for epidemics is of great importance, since they are useful tools to study the underlying outbreak numbers and allow one to test the ...
arxiv +1 more source
Identification and Molecular Dynamic Simulation of Flavonoids from Mediterranean species of Oregano against the Zika NS2B-NS3 Protease [PDF]
The Zika virus, is an emerging infectious disease causing severe complications such as microcephaly in infants and Guillain Barre syndrome in adults. There is no licensed vaccination or approved medicine to treat ZIKV infection. Therefore, extensive research is being carried out to find compounds that can be used effectively as therapeutic molecules to
arxiv +1 more source
Odds are the sign is right [PDF]
This article introduces a new condition based on odds ratios for sensitivity analysis. The analysis involves the average effect of a treatment or exposure on a response or outcome with estimates adjusted for and conditional on a single, unmeasured, dichotomous covariate.
arxiv +1 more source
The occurrence of fetal and neonatal disorders in pregnant women with Zika virus infection in the literature is not consistent. This study aims to estimate the prevalence rate of these disorders in fetuses/neonates of pregnant women with confirmed or ...
M. Martins+5 more
semanticscholar +1 more source
Management of infection by the Zika virus [PDF]
A panel of national experts was convened by the Brazilian Infectious Diseases Society in order to organize the national recommendations for the management of zika virus infection. The focus of this document is the diagnosis, both clinical and laboratorial, and appropriate treatment of the diverse manifestations of this infection, ranging from acute ...
Falcao, Melissa Barreto+16 more
openaire +4 more sources