Results 21 to 30 of about 658,068 (316)

A companion to the preclinical common data elements for rodent models of pediatric acquired epilepsy: A report of the TASK3‐WG1B, Pediatric and Genetic Models Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract Epilepsy syndromes during the early years of life may be attributed to an acquired insult, such as hypoxic–ischemic injury, infection, status epilepticus, or brain trauma. These conditions are frequently modeled in experimental rodents to delineate mechanisms of epileptogenesis and investigate novel therapeutic strategies.
Anna‐Maria Katsarou, Hana Kubova, Stéphane Auvin, Massimo Mantegazza, Melissa Barker‐Haliski, Aristea S. Galanopoulou, Christopher A. Reid, Bridgette D. Semple   +7 more
wiley   +1 more source

Zika virus infection enhances future risk of severe dengue disease

Science, 2020
Double whammy Dengue and Zika virus epidemics have been lapping each other around the globe. These are closely related mosquito-borne viruses with about 40% homology within the envelope protein.
L. Katzelnick, César Narvaez, Sonia Arguello, Brenda Lopez Mercado, Damaris Collado, Oscarlett Ampie, Douglas Elizondo, Tatiana Miranda, Fausto Bustos Carillo, J. Mercado, Krista Latta, Amy J Schiller, Bruno Segovia-Chumbez, S. Ojeda, N. Sanchez, M. Plazaola, J. Coloma, M. Halloran, L. Premkumar, A. Gordon, Federico Narvaez, A. D. de Silva, G. Kuan, Á. Balmaseda, E. Harris   +24 more
semanticscholar   +1 more source

Neuropathology of Zika Virus Infection [PDF]

Journal of Neuroinfectious Diseases, 2016
Zika virus (ZIKV) is a member of the Flaviviridae family that had been associated only with mild disease prior to the 2015 outbreak in Brazil. A dramatic increase in reported cases of microcephaly and Guillain-Barré syndrome during this time prompted significant research into possible associations with ZIKV and its neurotropic properties.
Rebecca D. Folkerth, Isaac H. Solomon, Danny A. Milner   +2 more
openaire   +3 more sources

Epidemiology of Zika Virus Infection [PDF]

The Journal of Infectious Diseases, 2017
Long known to be endemic in Africa and Southeast Asia and a rare cause of acute febrile illness, Zika virus (ZIKAV) arose from obscurity when an Asian genotype ZIKAV caused an outbreak of mild febrile illness in 2007 in Yap State, Federated States of Micronesia.
Marc Fischer, Susan L. Hills, Lyle R. Petersen   +2 more
openaire   +3 more sources

Insect‐specific viruses used in biocontrol of mosquito‐borne diseases

Interdisciplinary Medicine, Volume 1, Issue 1, January 2023., 2023
Insect‐specific RNA viruses (ISRVs) are involved in a wide range of families including Flaviviridae, Bunyaviridae, Negeviruses, Togaviridae, Reoviridae, Mesoniviridae, and Rhabdoviridae, which cannot infect vertebrates, including humans. However, ISRVs can infect and replicate in mosquitoes, interfering with the replication of mosquito‐borne viruses ...
Jiating Chen, Shengqun Deng, Hongjuan Peng   +2 more
wiley   +1 more source

Lack of Durable Cross-Neutralizing Antibodies Against Zika Virus from Dengue Virus Infection

Emerging Infectious Diseases, 2017
Cross-reactive antibodies elicited by dengue virus (DENV) infection might affect Zika virus infection and confound serologic tests. Recent data demonstrate neutralization of Zika virus by monoclonal antibodies or human serum collected early after DENV ...
Matthew H. Collins, Eileen McGowan, Ramesh Jadi, Ellen Young, Cesar A. Lopez, Ralph S. Baric, Helen M. Lazear, Aravinda M. de Silva   +7 more
doaj   +1 more source

Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes

Scientific Reports, 2020
Zika virus (ZIKV) has been extensively studied since it was linked to congenital malformations, and recent research has revealed that astrocytes are targets of ZIKV.
P. F. Ledur, Karina Karmirian, C. Pedrosa, Leticia R. Q. Souza, Gabriela Assis-de-Lemos, Thiago Martino Martins, J. Ferreira, Gabriel Ferreira de Azevedo Reis, E. S. Silva, D. Silva, J. Salerno, I. Ornelas, S. Devalle, R. F. Madeiro da Costa, L. Goto-Silva, L. Higa, A. Melo, A. Tanuri, L. Chimelli, M. M. Murata, P. Garcez, E. Filippi-Chiela, A. Galina, H. Borges, S. Rehen   +24 more
semanticscholar   +1 more source

A comprehensive review of Zika virus infection

The Journal of Qazvin University of Medical Sciences, 2018
Zika virus is a mosquito-borne flavivirus that is becoming a new global threat. Currently, serologic (ELISA) and molecular (RT-PCR) testing make the diagnosis of Zika virus infection.
Ahmad Tavakoli, Maryam Esghaei, Mohammad Hadi Karbalaie Niya, Arezoo Marjani, Alireza Tabibzadeh, Mohammad Karimzadeh, Seyed Hamidreza Monavari   +6 more
doaj   +1 more source

Zika Virus Infection in Pregnant Women in Rio de Janeiro — Preliminary Report

Yearbook of Pediatrics, 2016
BackgroundZika virus (ZIKV) has been linked to central nervous system malformations in fetuses. To characterize the spectrum of ZIKV disease in pregnant women and infants, we followed patients in Rio de Janeiro to describe clinical manifestations in ...
A. Act, P. Brasil, J. Pereira, C. Gabaglia, L. Damasceno, M. Wakimoto, R. M. Nogueira, P. Sequeira, A. Siqueira, L. Carvalho, D. C. Cunha, G. Calvet, E. Neves, M. E. Moreira, A. Baião, P. Carvalho, C. Janzen, S. Valderramos, J. Cherry, A. M. Filippis, K. Nielsen‐Saines   +20 more
semanticscholar   +1 more source

Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection

Science, 2016
Characterizing the Zika virus antibody response Given the public health emergency that Zika virus poses, scientists are seeking to understand the Zika-specific immune response. Stettler et al.
Karin Stettler, M. Beltramello, Diego A. Espinosa, Victoria A. Graham, Antonino Cassotta, S. Bianchi, Fabrizia Vanzetta, A. Minola, S. Jaconi, F. Mele, Mathilde Foglierini, M. Pedotti, L. Simonelli, S. Dowall, B. Atkinson, E. Percivalle, C. Simmons, L. Varani, J. Blum, F. Baldanti, E. Cameroni, R. Hewson, E. Harris, A. Lanzavecchia, F. Sallusto, D. Corti   +25 more
semanticscholar   +1 more source