Results 51 to 60 of about 182,639 (263)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Synthesis, Electrochemical Properties and Spectroscopic Studies of Mono and Dinuclear Zn(II) Polypyridyl Complexes with Phenylcyanamide Ligands [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2009
Several novel mononuclear Zn(II) complexes, [Zn(bpy)L2], where bpy=2,2’-bipyridine and L=monoanions of phenylcyanamide (pcyd), 4-methylphenylcyanamide (4-Mepcyd), 3,5-dimethylphenylcyanamide(3,5-Me2pcyd),4-methoxyphenylcyanamide(4-MeOpcyd), 3,5-dimeth ...
Alireza Rezvani, Hassan Hadadzadeh
doaj  

Synthesis, Crystal Structure, Spectroscopic Properties, and Interaction with Ct-DNA of Zn(II) with 2-Aminoethanethiol Hydrochloride Ligand

open access: yesBioinorganic Chemistry and Applications, 2016
The zinc(II) complex (C2H6NS)2Zn·ZnCl2 was synthesized with 2-aminoethanethiol hydrochloride and zinc sulfate heptahydrate as the raw materials in aqueous solution.
Xu-gang Shu   +5 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

catena-Poly[[bis(3-benzoylpyridine-κN)zinc(II)]-di-μ-dicyanamido-κ4N1:N5]

open access: yesActa Crystallographica Section E, 2008
The title compound, [Zn(C2N3)2(C12H9NO)2]n, is a polymeric zinc(II) complex with the metal ion located on an inversion centre. The ZnII ion is six-coordinated by two N atoms of two 3-benzoylpyridine ligands and four N atoms from four dicyanamide ligands,
Fei Yu, Zhong-Shu Li, Bai-Wang Sun
doaj   +1 more source

Zinc (II) Complexes with Substituted Pyridines

open access: yes, 1967
As a part of a series of investigations on several d10 metal complexes, we have now studied some di­valent zinc complexes with nitrogen ligands. The complexes of zinc halides with\(\gamma\)-picoline were known long back and the ligand was purified by Forming a complex with zinc halides and then distilling it.
S. Guru, D. V. Ramana Rao
openaire   +2 more sources

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

Studies of zinc(II) in pharmaceutical and biological samples by extractive spectrophotometry: using pyridoxal-4-phenyl-3-thiosemicarbazone as chelating reagent

open access: yesJournal of the Brazilian Chemical Society, 2006
Pyridoxal-4-phenyl-3-thiosemicarbazone (PPT) is proposed as a new sensitive reagent for the sensitive extractive spectrophotometric determination of zinc(II).
Sarma L. Subramanyam   +4 more
doaj  

The synthesis and structural properties of a chloridobis{N-[(4-methoxyphenyl)imino]pyrrolidine-1-carboxamide}zinc(II) (acetonitrile)trichloridozincate coordination complex

open access: yesActa Crystallographica Section E: Crystallographic Communications
The title complex, [ZnCl(C12H15N3O2)2][ZnCl3(CH3CN)], was synthesized and its structure was fully characterized through single-crystal X-ray diffraction analysis.
Laxmi Tiwari, Kristopher V Waynant
doaj   +1 more source

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