Results 1 to 10 of about 12,514 (165)

Efficacy of Different Combination Therapies for Mania in Bipolar Disorder: A Systematic Review and Meta‐Analysis [PDF]

open access: yesBrain and Behavior
Objective To systematically evaluate the efficacy and safety of different combination therapies in the treatment of mania in bipolar disorder, and to provide evidence‐based support for individualized clinical treatment.
Peiling Yao, Pingan Ni, Liqin Yin
doaj   +2 more sources

Comparison of ziprasidone and olanzapine on cognitive function in patients with schizophrenia at different stages: a prospective study in Huai’an, China [PDF]

open access: yesFrontiers in Behavioral Neuroscience
ObjectiveTo compare the effects of ziprasidone and olanzapine on cognitive function in patients with first-episode schizophrenia and chronic schizophrenia at different stages.MethodsCognitive function tests were performed on chronic schizophrenic ...
Jingjing Yao   +7 more
doaj   +2 more sources

Impact of CYP3A4 functional variability on ziprasidone metabolism [PDF]

open access: yesFrontiers in Pharmacology
IntroductionZiprasidone is primarily metabolized by CYP3A4, an enzyme with genetic variability and susceptibility to inhibition or induction. This study explored the functional variability of CYP3A4 in ziprasidone metabolism, focusing on drug ...
Qi Zhou   +8 more
doaj   +2 more sources

Efficacy and Tolerance of Antipsychotics Used for the Treatment of Patients Newly Diagnosed with Schizophrenia: A Systematic Review and Meta-Analysis

open access: yesPharmacy, 2023
This systematic review compared the efficacy and tolerance of oral antipsychotics (APDs) used in the treatment of schizophrenia following the PRISMA-P© statement (n = 21).
Zina Sherzad Qadir   +2 more
doaj   +1 more source

Ziprasidone Induces Rabbit Atrium Arrhythmogenesis via Modification of Oxidative Stress and Sodium/Calcium Homeostasis

open access: yesBiomedicines, 2022
Background: Atypical antipsychotics increase the risk of atrial arrhythmias and sudden cardiac death. This study investigated whether ziprasidone, a second-generation antipsychotic, affected intracellular Ca2+ and Na+ regulation and oxidative stress ...
Buh-Yuan Tai   +4 more
doaj   +1 more source

Efficacy and Tolerability of Ziprasidone Use in Children and Adolescents, a Systemic Review and Meta Analysis

open access: yesEuropean Psychiatry, 2022
Introduction Ziprasidone is an atypical antipsychotic that has demonstrated efficacy for the treatment of bipolar disorder and schizophrenia. There is some preliminary evidence for Ziprasidone use in children and adolescents with several open label ...
A. Wadhwa   +3 more
doaj   +1 more source

Tolerability of Ziprasidone Use in Children and Adolescents: A Prisma Model: Systematic Review and Meta-Analysis

open access: yesEuropean Psychiatry, 2022
Introduction Studies have demonstrated that Ziprasidone use may be beneficial in children. Determining its potential risks and benefits when used in children is therefore important.
J. Jay   +7 more
doaj   +1 more source

Behavioral and metabolic effects of the atypical antipsychotic ziprasidone on the nematode Caenorhabditis elegans. [PDF]

open access: yesPLoS ONE, 2013
Atypical antipsychotics are associated with metabolic syndrome, primarily associated with weight gain. The effects of Ziprasidone, an atypical antipsychotic, on metabolic syndrome has yet to be evaluated.
Priscila Gubert   +6 more
doaj   +1 more source

Significance of Ziprasidone Nanoparticles in Psychotic Disorders

open access: yesMaterials Proceedings, 2023
Nanotechnology is used today in a wide range of industries. Weakly water-soluble medications have better solubility and bioavailability when delivered by nano-specific drug delivery methods, such as nanocrystals.
Mamta Patil   +4 more
doaj   +1 more source

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