Antipsychotic switching in bipolar disorders: a systematic review. [PDF]
, 2017 With the increasingly widespread use of antipsychotics in bipolar disorder (BD), switching among these agents and between antipsychotics and mood stabilizers has become more common, in particular, since the introduction of the novel atypical ...
Bernardo Arroyo, Miquel +5 more
core +4 more sources
Application of a single-objective, hybrid genetic algorithm approach to pharmacokinetic model building. [PDF]
, 2012 A limitation in traditional stepwise population pharmacokinetic model building is the difficulty in handling interactions between model components. To address this issue, a method was previously introduced which couples NONMEM parameter estimation and ...
Belani, Chandra P +12 more
core +3 more sources
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness [PDF]
, 2018 BACKGROUND: There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute ...
Bernard, G.R. +31 more
core +1 more source
Dopamine D2/3 occupancy of ziprasidone across a day : a within-subject PET study [PDF]
, 2013 Rationale Ziprasidone is an atypical antipsychotic recommended to be administered twice daily. Objectives The purpose of this study was to investigate whether occupancy of the dopamine D2/3 receptors by ziprasidone is maintained across a day ...
Borlido, Carol +10 more
core +1 more source
Effects of haloperidol and atypical neuroleptics on psychomotor performance and driving ability in schizophrenic patients - Results from an experimental study [PDF]
, 2003 The influence of antipsychotic treatment on the neuropsychological and psychomotor performance of schizophrenic patients is still a subject of investigation.
Kagerer, S. +3 more
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Continuing lack of evidence for the psychotic subtyping of PTSD [PDF]
, 2011 Universidade Federal de São Paulo, Dept Psychiat, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Psychiat, São Paulo, BrazilWeb of ...
Asevedo, Elson +4 more
core +1 more source
Tardive Dyskinesia in Relation to Estimated Dopamine D2 Receptor Occupancy in Patients with Schizophrenia: Analysis of the CATIE data [PDF]
, 2014 Objective The objective of this study was to evaluate the relationship between antipsychotic-induced tardive dyskinesia (TD) and estimated dopamine D2 receptor occupancy levels in patients with schizophrenia, using the dataset from the Clinical ...
Bies, Robert R. +7 more
core +2 more sources
The effects of typical and atypical antipsychotics on the electrical activity of the brain in a rat model [PDF]
, 2013 Objective: Antipsychotic drugs are known to have strongeffect on the bioelectric activity in the brain. However,some studies addressing the changes on electroencephalography(EEG) caused by typical and atypical antipsychoticdrugs are conflicting. We aimed
Mustafa Yılmaz, Oytun Erbaş
core +1 more source
Antipsychotics and Torsadogenic Risk: Signals Emerging from the US FDA Adverse Event Reporting System Database [PDF]
, 2013 Background: Drug-induced torsades de pointes (TdP) and related clinical entities represent a current regulatory and clinical burden. Objective: As part of the FP7 ARITMO (Arrhythmogenic Potential of Drugs) project, we explored the publicly available US ...
A Bate +53 more
core +4 more sources