Results 41 to 50 of about 12,399 (131)

Advances in Enaminomaleimides Chemistry: Synthesis, Chemical Applications, and Perspectives

ChemistryEurope, Volume 3, Issue 5, September 18, 2025.
Enaminomaleimides are versatile building blocks for the construction of functionalized heterocycles. Their unique nucleophilic character, contrasting with the classical electrophilic nature of maleimides, enables diverse synthetic applications, showing promising potential in both materials science and medicinal chemistry.
Adrián López‐Francés, Birane Diop, Xingyu Jiang, Jean Rodriguez, Muriel Amatore, Thierry Constantieux   +5 more
wiley   +1 more source

Treatment of Early‐Onset Specified and Unspecified Bipolar Disorders: A Systematic Review and Strategies for Identifying and Managing a Thermally Dysregulated Subtype in Children

Acta Psychiatrica Scandinavica, Volume 152, Issue 3, Page 156-179, September 2025.
ABSTRACT Introduction Bipolar disorder (BD), characterized by extreme mood shifts between mania and depression, can manifest in childhood, and pose treatment challenges. Treatment for full‐criteria BD I or II in children has been partially described in the literature, but major uncertainties exist regarding non‐classic presentations, which were ...
Demitri F. Papolos, Martin H. Teicher, Robert M. Post   +2 more
wiley   +1 more source

Personalized medicine : the impact on chemistry [PDF]

, 2010
An effective strategy for personalized medicine requires a major conceptual change in the development and application of therapeutics. In this article, we argue that further advances in this field should be made with reference to another conceptual shift,
Marsh, Andrew, Singer, Donald R. J., Taylor, Paul C., Watkins, John   +3 more
core   +1 more source

Age and Sex Differences in Adverse Events Associated With Antipsychotics: An Analysis of the FDA Adverse Events Database

International Journal of Geriatric Psychiatry, Volume 40, Issue 8, August 2025.
ABSTRACT Objectives While the risks of antipsychotics in older adults are well recognized, clinical trials often exclude frail older patients, have short follow‐up periods, and provide limited comparative data on specific drugs. This study aimed to explore age‐related differences in the adverse effects of six commonly prescribed antipsychotics using a ...
Tabea Ramin, Jens‐Uwe Peter, Michael Schneider, Volker Dahling, Oliver Zolk   +4 more
wiley   +1 more source

Changes in Physician Antipsychotic Prescribing Preferences, 2002–2007 [PDF]

, 2014
Objective Physician antipsychotic prescribing behavior may be influenced by comparative effectiveness evidence, regulatory warnings, and formulary and other restrictions on these drugs.
Berndt, Ernst R., Donohue, Julie, Horvitz-Lennon, Marcela, Huskamp, Haiden A., O'Malley, A. James, Taub, Anna Levine   +5 more
core   +1 more source

Genome‐wide associations with metabolic syndrome among UK Biobank participants reporting use of second‐generation antipsychotics

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 8, Page 476-485, August 2025.
Abstract Objectives Second‐generation antipsychotic (SGA) medications are frequently prescribed for mental health conditions; however, they are associated with an increased risk of metabolic syndrome (MetS). We aimed to identify genetic associations of SGA‐associated MetS (SGA–MetS) using genome‐wide approaches within the UK Biobank. We also set out to
Nihal El Rouby, Aniwaa Owusu‐Obeng, Michael Preuss, Simon Lee, Mingjian Shi, Michael Lape, Lisa J. Martin, Bahram Namjou‐Khales, Leah C. Kottyan, Sara L. Van Driest, Jonathan D. Mosley, Melissa P. DelBello   +11 more
wiley   +1 more source

Nanotechnology versus other techniques in improving drug dissolution [PDF]

, 2014
postprin
Chan, HK, Kwok, PCL
core   +1 more source

Effectiveness of antipsychotics used in first-episode psychosis: a naturalistic cohort study [PDF]

, 2016
Background: One year of antipsychotic treatment from symptom remission is recommended following a first episode of psychosis (FEP). Aims: To investigate the effectiveness of commonly used antipsychotic medications in FEP.
Ayadurai, Nirmalan, Harris, Michael, Jethwa, Ketan, Jones, Christopher I, Kavanagh, Gail, Marwaha, Steven, Thompson, Andrew, Whale, Richard, Wickramasinghe, Vijitha   +8 more
core   +4 more sources

Oral Adverse Effects of Antipsychotic Medications: A Case/Noncase Analysis of EudraVigilance Data

Oral Diseases, Volume 31, Issue 8, Page 2630-2640, August 2025.
ABSTRACT Objective Neuropsychiatric disorders are associated with poor oral health, with antipsychotics as potential contributors. This study aimed to analyse the oral adverse effects of antipsychotics using the EudraVigilance database. Methods A case/noncase analysis was conducted to calculate reporting odds ratios (ROR) and assess the ...
Leire Urien, Unax Lertxundi, Montserrat Garcia, Carmelo Aguirre, Nerea Jauregizar, Teresa Morera‐Herreras   +5 more
wiley   +1 more source

Medication Causes and Treatment of Delirium in Patients With and Without Dementia

Brain and Behavior, Volume 15, Issue 7, July 2025.
Medication associated risk related to cause and treatment of delirium ABSTRACT Introduction Medication associated with delirium in adult patients is poorly understood and considered both a predisposing and precipitating factor. Prescribing advice is lacking. This systematic review aims to collate evidence on medication risks in delirium associated with
Anita Elaine Weidmann, Rut Matthíasdóttir, Guðný Björk Proppé, Ivana Tadić, Pétur Sigurdur Gunnarsson, Freyja Jónsdóttir   +5 more
wiley   +1 more source