Results 171 to 180 of about 18,826 (294)
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang +10 more
wiley +1 more source
ST2<sup>+</sup> Erythroid Progenitors Suppress Allergic Asthma by Scavenging IL-33 in Young Mice. [PDF]
Li C +7 more
europepmc +1 more source
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou +6 more
wiley +1 more source
Protocol for immunomagnetic enrichment of T cells from complex murine tissues. [PDF]
Trolio E, Duong L, Lucas M, Prosser A.
europepmc +1 more source
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo +8 more
wiley +1 more source
Protocol for immunomagnetic enrichment of CD8 T cells from complex murine tissues. [PDF]
Trolio E, Duong L, Lucas M, Prosser A.
europepmc +1 more source
Excerpt Zombies are generally understood as beings trapped in limbo between life and death, and have historically been associated with the Haitian practice of Vodoun.
Shaw-Nevins, Andrea Elizabeth
core
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang +19 more
wiley +1 more source
Making deep immunophenotyping accessible: the successful application of a guided 23-parameter mouse immunophenotyping panel package provided through a shared resource. [PDF]
Isbell MG +26 more
europepmc +1 more source

