Results 91 to 100 of about 777,832 (173)

A Confirmatory, Dual Center Nonhuman Primate Study on the Efficacy of Novel Oropharyngeal Spray Immunization With an Adenoviral Vector Vaccine Against RSV—Important Lessons Learned

open access: yesJournal of Medical Primatology, Volume 55, Issue 6, December 2026.
ABSTRACT Background In a randomized, blinded, dual center study across two European primate research facilities, we evaluated the immunogenicity and protective efficacy of a DNA prime—oropharyngeal adenoviral boost vaccination strategy against respiratory syncytial virus (RSV).
Matthias Tenbusch   +15 more
wiley   +1 more source

Commercial bank digital transformation, information costs, and corporate financial constraints

open access: yesChina Journal of Accounting Studies
The rapid development of digital finance has transformed traditional financial institutions. We investigate the effect and economic consequences of bank digital transformation on corporate financial constraints using data from China.
Xiaoxi Li, Qinger Zhong, Guochao Yang
doaj   +1 more source

Photoacoustic Nanotagging for In Vivo Tracking and Optimization of Macrophage Immunotherapy in Solid Tumors

open access: yesAdvanced Materials, Volume 38, Issue 61, 2 November 2026.
Macrophage‐based immunotherapy for solid tumors is limited by poor tracking of cell localization and persistence. This study introduces nanotagged macrophages enabling near‐infrared photoacoustic imaging for real‐time monitoring. IFNγ‐conjugated tags enhance antitumor polarization without harming viability.
Seoyoon Song   +8 more
wiley   +1 more source

B Cell Deficiency Protects Against the Development of c‐MET and Beta‐Catenin Driven Hepatocellular Carcinoma in Mice

open access: yesCell Biology International, Volume 50, Issue 11, November 2026.
ABSTRACT Hepatocellular carcinoma (HCC), a lethal form of liver cancer, continues to show rising mortality rates despite advancements in immunotherapies. This highlights the need for more effective treatments. Recent studies linked the presence of B cells within human tumors, including HCC, to improved responses to immunotherapy and better prognoses ...
Fang Wang   +3 more
wiley   +1 more source

Insolvent firms and systemic vulnerability: Identification and financial stability implications in Kazakhstan

open access: yesInternational Review of Economics & Finance
This paper offers new empirical insights into the identification and implications of firm insolvency from a developing economy perspective. We employ two identification strategies to detect insolvent firms.
Zhandos Ybrayev   +3 more
doaj   +1 more source

An Orthotopic Xenograft Model for Preclinical Evaluation of CAR T Cell Therapy in Glioblastoma

open access: yesCurrent Protocols, Volume 6, Issue 11, November 2026.
Abstract Glioblastoma (GBM) is the most lethal primary brain tumor in adults, and despite intensive research efforts, effective therapeutic breakthroughs remain elusive. Consequently, the standard of care has remained largely unchanged for nearly 30 years, underscoring the need for robust preclinical models to evaluate experimental therapies.
Julian Hübner   +6 more
wiley   +1 more source

COVID-19: guaranteed Loans and Zombie Firms. [PDF]

open access: yesCESifo Econ Stud, 2020
Zoller-Rydzek B, Keller F.
europepmc   +1 more source

The Investigation of Zombie Firms’ Existence in Borsa İstanbul Manufacturing Industry

open access: yes, 2020
Introduction: The word “zombie” is associated with the “living dead” in our minds from horror movies we watch on TV. Recently, this concept has been used frequently to identify the firms that are still standing while they should have been closed long ago.
Kaplanoğlu E.   +3 more
core   +1 more source

MEK1/2 Signalling establishes an alloreactive effector T cell program through SMAD4 during cardiac allograft rejection

open access: yesClinical and Translational Medicine, Volume 16, Issue 11, November 2026.
Upon T cell receptor (TCR) engagement by alloantigens, MEK1/2–ERK1/2 signalling promotes SMAD4 nuclear translocation and supports SMAD4‐dependent transcription of effector genes, including Ifng, Tnf, and Il2ra. This transcriptional program promotes alloreactive T cell effector function and contributes to cardiac allograft rejection.
Jiulu Zhao   +8 more
wiley   +1 more source

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