Results 51 to 60 of about 358,589 (345)

ICE EFFECT ON COAST AND SEABED IN BAYDARATSKAYA BAY, KARA SEA

open access: yesGeography, Environment, Sustainability, 2013
For the engineering design of underwater pipelines and communication cables in freezing seas, reliable estimates of the frequency and penetration depth of ice-keel scour on the seabed and shoreface are required.
Stanislav Ogorodov   +5 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Environmental Fragility Zoning Using GIS and AHP Modeling: Perspectives for the Conservation of Natural Ecosystems in Brazil [PDF]

open access: gold, 2022
Luciano Cavalcante de Jesus França   +7 more
openalex   +1 more source

Zoning for Solar Energy: Resource Guide [PDF]

open access: yes, 2015
This document is designed to help New York State localities amend zoning and other land use regulations to permit the development of solar energy systems in their jurisdictions.
Bacher, Jessica A., Nolon, John R.
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Potencial agroclimático para a Alpinia purpurata, no Estado de Pernambuco Agroclimatic potencial for Alpinia purpurata in the State of Pernambuco

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2009
Objetivou-se realizar o zoneamento agroclimático do Estado de Pernambuco, visando dar subsídios à seleção de locais para a implantação da flor tropical Alpinia purpurata.
Sérgio R. R. Medeiros   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Історія і перспективи районування та реєстрації сортів волоського горіха (Juglans regia L.) в Україні

open access: yesPlant Varieties Studying and Protection, 2018
Мета. Дослідити історію районування і реєстрації сортів волоського горіха в Україні. Результати. Волоський горіх з’явився в районованому сортименті 1937 р. з рекомендаціями до вирощування його в сприятливих умовах Південного Сходу України.
В. М. Меженський
doaj   +1 more source

Mapping Land Subsidence Hazard through InSAR (Case study: Kashmar and Khalil Abad plain) [PDF]

open access: yesمدیریت بیابان, 2019
Measuring of subsidence is often challenging due to the gradual occurrence in large-scale, and advanced measuring techniques are required. The first foresighted consequence of this catastrophic phenomenon is irreversible loss of aquifer reservoir ...
Hamid Kohbanani   +2 more
doaj   +1 more source

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