Microbiological Screening of 5-Functionalized Pyrazoles for the Future Development of Optimized Pyrazole-Based Delivery Systems. [PDF]
Brullo C +6 more
europepmc +1 more source
Pharmacodynamics of Zoxazolamine and Chlorzoxazone in Rats
Zoxazolamine is used for the pharmacologic assessment of possible changes in oxidative enzyme activity (paralysis time test) in rodents, whereas one of its metabolites, chlorzoxazone, is used clinically as a skeletal muscle relaxant. In this investigation, the pharmacodynamics of the two compounds were characterized in normal adult rats to determine ...
openaire
Development of Novel Sulfonamide-Based Pyrazole-Clubbed Pyrazoline Derivatives: Synthesis, Biological Evaluation, and Molecular Docking Study. [PDF]
Zala M +5 more
europepmc +1 more source
Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liver. [PDF]
Chen WD +6 more
europepmc +1 more source
SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism. [PDF]
Chen T +8 more
europepmc +1 more source
Phenobarbital Treatment at a Neonatal Age Results in Decreased Efficacy of Omeprazole in Adult Mice. [PDF]
Tien YC, Piekos SC, Pope C, Zhong XB.
europepmc +1 more source
A Review of the Phytochemistry, Molecular Docking, Pharmacology, Toxicology, Ethnopharmacology, Botany, and Clinical Studies of <i>Maytenus senegalensis</i> (Lam.) Excell. [PDF]
Ramadwa TE, Meddows-Taylor S.
europepmc +1 more source
Identification of a novel potassium channel (GiK) as a potential drug target in Giardia lamblia: Computational descriptions of binding sites. [PDF]
Palomo-Ligas L +5 more
europepmc +1 more source
Role of high-fat diet in regulation of gene expression of drug metabolizing enzymes and transporters. [PDF]
Ghose R +7 more
europepmc +1 more source
[Observations on the uricosuric activity of zoxazolamine].
G, RATTI, E, CIRLA
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