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Kinetics of drug action in disease states: towards physiology-based pharmacodynamic (PBPD) models. [PDF]
Danhof M.
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Advancements in the design and development of pyrazoline-based antimycobacterial agents: an update and future perspectives. [PDF]
Rakshit G +3 more
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Constitutive androstane receptor mediates the induction of drug metabolism in mouse models of type 1 diabetes. [PDF]
Dong B, Qatanani M, Moore DD.
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Pharmacotherapy for hyperuricemia in hypertensive patients. [PDF]
Gois PHF, Souza ERM.
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Design, synthesis and biological evaluation of benzoxazolinone-containing 1,3,4-thiadiazoles as TNF-α inhibitors. [PDF]
Haider S +4 more
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Hyperuricemia and Hypertension: Links and Risks. [PDF]
Stewart DJ, Langlois V, Noone D.
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Common and Uncommon Mouse Models of Growth Hormone Deficiency.
List EO +5 more
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Zoxazolamine — A Potent Uricosuric Agent
New England Journal of Medicine, 1958ZOXAZOLAMINE¶ has been widely used during the past two years for the purpose of decreasing spasm of skeletal muscle, presumably via a depressant effect upon polysynaptic pathways in the central nervous system. Occasional side effects, such as drowsiness, lightheadedness, dizziness, abdominal discomfort, vomiting, headache and transient blotching of the
E B, Reed, T V, Feichtmeir, F M, Willett
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ZOXAZOLAMINE (FLEXIN) IN RHEUMATIC DISEASES
Journal of the American Medical Association, 1956• Zoxazolamine prevents or relieves spasm in voluntary muscles by depressing the central nervous pathways involved. It was administered by mouth to 100 rheumatic patients in whom the muscular stiffness and soreness made it impossible to carry out the necessary program of exercise. Relief of the stiffness and aching was often complete within 30 minutes
R T, SMITH +3 more
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