Results 41 to 50 of about 132,707 (291)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Comparative study of Uranium diffusion in Zry-4 and pure α-Zr [PDF]

, 2018
Throughout the α-spectrometry U diffusion in pure Zry-4 was studied and compared with pure α-Zr in the temperature range 843-1093 K in order to analyze the diffusion process in both matrices.
Jorge Apostol Gordillo (5554178), Nicolás Di Lalla (5552531), Manuel Iribarren (5552525), Rodolfo Ariel Pérez (5552528)   +3 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Stress Distribution on Bone Due to Dental Implant

Journal of Pharmacy and Bioallied Sciences
Background: The distribution of stress (DS) in the bone around dental implant (DI) during loading is associated with success. In contrast, upon loosening of DI because of high stress, leads to its failure.
Ajay Gaikwad, Lishoy W Rodrigues, Karuna Gajanan Pawashe, Praveen Gangadharappa, Amit Bajirao Jadhav, Shruti Dabi   +5 more
doaj   +1 more source

Effect of Zr on microstructure and properties of TC4 alloy fabricated by laser additive manufacturing

Journal of Materials Research and Technology, 2023
In this paper, the effect of Zr on the microstructure of laser additive manufactured Ti–6Al–4V (TC4) alloy is studied by adding different contents of Zr (0%, 15%, 30%, 45%), and the mechanisms of strengthening and corrosion passivation are also discussed.
X.J. Jiang, S.J. Bao, L.W. Zhang, X.Y. Zhang, L.S. Jiao, H.B. Qi, F. Wang   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Zr-Poisoning of Grain Refiner Particles Studied in Al-Ni-Zr Amorphous Alloys [PDF]

, 2013
Zr-Poisoning of Grain Refiner Particles Studied in Al-Ni-Zr Amorphous ...
AM Bunn (14530730), Pavel Cizek (13088826), P Schumacher (13641151)   +2 more
core  

Recent Advances in the Grain Refinement Effects of Zr on Mg Alloys: A Review

Metals, 2022
As the lightest structural materials, Mg alloys show great effectiveness at energy saving and emission reduction when applied in the automotive and aerospace fields.
Ming Sun, Depeng Yang, Yu Zhang, Lin Mao, Xikuo Li, Song Pang   +5 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

K1-ZR/midas-vt-pro: MIDAS-VT-Pro [PDF]

, 2018
<ul> <li><a href="https://github.com/K1-ZR/midas-vt-pro/blob/master/MIDAS-VT-User'sGuide.pdf"><strong>User's guide</strong></a> </li> <li><a href="https://github.com/K1-ZR/midas-vt-pro/blob/master ...
Keyvan Zare-Rami
core   +1 more source