Preliminary study of the toxicity and radioprotective effects of zymosan in vitro and in vivo [PDF]
BMC Pharmacology and Toxicology, 2021 Background This study aimed to confirm the cytotoxicity of zymosan in vitro and in vivo and determine the appropriate treatment time and the dose of zymosan. Methods AHH-1 cells and HIECs were administered by 0, 20, 40, 80 or 160 μg/mL zymosan. The CCK-8
Yue-zhi Zhang +4 more
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Efeito de inibidores da sintase de óxido nítrico na dor inflamatória articular e influxo celular da artrite induzida por zymosan em ratos [PDF]
Revista Brasileira de Reumatologia, 2003 OBJETIVO: Investigar o papel do óxido nítrico (NO) no influxo celular (IC) e a incapacitação articular (IA) na artrite por zymosan (AZy). MÉTODOS: Ratos Wistar receberam injeção de Zy (1mg) no joelho direito. Grupos-controles receberam salina.
Francisco Airton Castro da Rocha +5 more
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Forsythoside A Modulates Zymosan-Induced Peritonitis in Mice [PDF]
Molecules, 2018 Acute inflammation is a protective response of the host to physical injury and invading infection. Timely treatment of acute inflammatory reactions is essential to prevent damage to organisms that can eventually lead to chronic inflammation. Forsythoside
Xiao-Tian Zhang +4 more
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Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan [PDF]
European Journal of Immunology, 2007 Emma C Slack, Caetano Reis e Sousa
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Effect of zymosan on the expression and function of the gap-junction protein connexin 43 in human corneal fibroblasts [PDF]
International Journal of Ophthalmology, 2021 AIM: To study the effect of zymosan, a ligand found on the surface of fungi, on gap junctional intercellular communication (GJIC) in cultured human corneal fibroblasts (HCFs).
Xiao-Shuo Zheng +7 more
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Hidden attributes of zymosan in the pathogenesis of inflammatory diseases: A tale of the fungal agent [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Inflammation triggers immune system-mediated actions that contribute to the development of multiple diseases. Zymosan, a polysaccharide derived from the Saccharomyces cerevisiae cell wall, is mainly made up of glucan and mannan residues and is used as an
Priyanka Arya +4 more
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Anti-PCSK9 monoclonal antibody attenuates high-fat diet and zymosan-induced vascular inflammation in C57BL/6 mice by modulating TLR2/NF-ƙB signaling pathway [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Excess intake of a high-fatty diet (HFD) together with zymosan administration mediates vasculitis response which leads to impaired serum lipid levels and causes arterial stiffness. In the development of new cholesterol-lowering medications,
Priyanka Arya +3 more
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Scientific Reports, 2021 Ankylosing spondylitis is a male-predominant disease and previous study revealed that estrogens have an anti-inflammatory effect on the spondyloarthritis (SpA) manifestations in zymosan-induced SKG mice.
Hyemin Jeong +5 more
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Zymosan-A promotes the regeneration of intestinal stem cells by upregulating ASCL2
Cell Death and Disease, 2022 Intestinal stem cells (ISCs) are responsible for intestinal tissue homeostasis and are important for the regeneration of the damaged intestinal epithelia. Through the establishment of ionizing radiation (IR) induced intestinal injury model, we found that
Jicong Du +9 more
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Marine Drugs, 2023 Fucans from marine algae have been the object of many studies that demonstrated a broad spectrum of biological activities, including anti-inflammatory effects. The aim of this study was to verify the protective effects of a fucan extracted from the brown
Ana Katarina Andrade Silva +7 more
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