Forsythoside A Modulates Zymosan-Induced Peritonitis in Mice [PDF]
Acute inflammation is a protective response of the host to physical injury and invading infection. Timely treatment of acute inflammatory reactions is essential to prevent damage to organisms that can eventually lead to chronic inflammation. Forsythoside A (FTA), an active constituent of Forsythia suspensa, has been reported to have anti-inflammatory ...
Ping Kang+4 more
doaj +6 more sources
Quercetin attenuates zymosan-induced arthritis in mice
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by articular lesions, recruitment of inflammatory cells and increased levels of pro-inflammatory cytokine. The intra-articular administration of zymosan is an experimental model that promotes inflammatory parameters resembling RA.
Felipe A Pinho-ribeiro+2 more
exaly +5 more sources
TLR2 modulates inflammation in zymosan-induced arthritis in mice [PDF]
AbstractThe interplay between the innate and acquired immune systems in chronic inflammation is not well documented. We have investigated the mechanisms of inflammation in murine zymosan-induced arthritis (ZIA) in the light of recent data on the roles of Toll-like receptor 2 (TLR2) and Dectin-1 in the activation of monocyte/macrophages by zymosan.
Frasnelli, M. E.+4 more
exaly +7 more sources
Effect of zymosan on the expression and function of the gap-junction protein connexin 43 in human corneal fibroblasts [PDF]
AIM: To study the effect of zymosan, a ligand found on the surface of fungi, on gap junctional intercellular communication (GJIC) in cultured human corneal fibroblasts (HCFs).
Dan Xu, Ye Liu
exaly +2 more sources
The mechanism for the radioprotective effects of zymosan‐A in mice [PDF]
AbstractIt proved that Zymosan‐A protected the haematopoietic system from radiation‐induced damage via Toll‐Like Receptor2 in our previous study. In this study, we investigated the potential mechanism for the radioprotective effects of Zymosan‐A. The mice were treated with Zymosan‐A (50 mg/kg, dissolved in NS) via peritoneal injection 24 and 2 hours ...
Jicong Du, Pei Zhang, Yanyong Yang
exaly +4 more sources
AIM: To investigate the effects of triptolide on proinflammatory cytokine and chemokine expression induced by the fungal component zymosan in cultured human corneal fibroblasts (HCFs). METHODS: HCFs were cultured in the absence or presence of zymosan or
Yang Liu+4 more
exaly +2 more sources
Study on the Therapeutic Effects and Mechanisms of Gintonin in Irritable Bowel Syndrome and Its Relationship with TRPV1, TRPV4, and NaV1.5. [PDF]
Irritable bowel syndrome (IBS) is a gastrointestinal (GI) disease accompanied by changes in bowel habits without any specific cause. Gintonin is a newly isolated glycoprotein from ginseng that is a lysophosphatidic acid (LPA) receptor ligand.
Choi NR+7 more
europepmc +2 more sources
The effects of dietary zymosan A on the growth performance and histological structure, digestive capacity, and microbiota were investigated in Litopenaeus vannamei, an important shrimp species used in aquaculture. L. vannamei (initial body weight = 0.41 ±
Yudong Zheng+10 more
exaly +3 more sources
β-1,3 Glucan Microparticles & Nanoparticles: Fabrication Methods & Applications in Immunomodulation & Targeted Drug Delivery. [PDF]
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Dowdall N, Hoare T.
europepmc +2 more sources
Hidden attributes of zymosan in the pathogenesis of inflammatory diseases: A tale of the fungal agent [PDF]
Inflammation triggers immune system-mediated actions that contribute to the development of multiple diseases. Zymosan, a polysaccharide derived from the Saccharomyces cerevisiae cell wall, is mainly made up of glucan and mannan residues and is used as an
Priyanka Arya+4 more
doaj +1 more source