Results 81 to 90 of about 40,088 (308)

Effect of Gedunin on Acute Articular Inflammation and Hypernociception in Mice

Molecules, 2015
Gedunin, a natural limonoid from Meliaceae species, has been previously described as an antiinflammatory compound in experimental models of allergic inflammation.
Fernando P. Conte, Fausto K. Ferraris, Thadeu E. M. M. Costa, Patricia Pacheco, Leonardo N. Seito, Waldiceu A. Verri Jr., Fernando Q. Cunha, Carmen Penido, Maria G. Henriques   +8 more
doaj   +1 more source

Mitofusin 2 Deficiency Causes Pro-Inflammatory Effects in Human Primary Macrophages

Frontiers in Immunology, 2021
Mitofusin 2 (MFN2) is a mitochondrial outer membrane GTPase, which modulates mitochondrial fusion and affects the interaction between endoplasmic reticulum and mitochondria.
Vera Khodzhaeva, Yannick Schreiber, Gerd Geisslinger, Gerd Geisslinger, Ralf P. Brandes, Bernhard Brüne, Bernhard Brüne, Bernhard Brüne, Bernhard Brüne, Dmitry Namgaladze   +9 more
doaj   +1 more source

The Synthetic LXR Agonist GW3965 Attenuates Phosgene‐Induced Acute Lung Injury Through the Modulation of PI3K/Akt and NF‐κB Signalling Pathways

Basic &Clinical Pharmacology &Toxicology, Volume 136, Issue 6, June 2025.
ABSTRACT Phosgene, used in large‐scale industrial production, is highly toxic and irritant. Accidental exposure can lead to varying degrees of injuries, with severe cases potentially resulting in acute lung injury or acute respiratory distress syndrome, resulting in a mortality rate of 40%–50%.
Dong Yan, Yuanwei Fu, Jie Mei, Junhong Wang, Ayijiang Jiamaliding, Ying Liu, Zanmei Zhao, Qingbian Ma   +7 more
wiley   +1 more source

The in vitro effects of resistin on the innate immune signaling pathway in isolated human subcutaneous adipocytes [PDF]

, 2007
Context: Obesity-associated inflammation is a contributory factor in the pathogenesis of type 2 diabetes mellitus (T2DM); the mechanisms underlying the progression to T2DM are unclear.
Adam R. Baker, Alison L. Harte, Aranda, Asensio, Baan, Banerjee, Bokarewa, Borst, Bradford, Christine M. Kusminski, Creely, Curat, Einstein, Ffolliott M. Fisher, Fu, Graveleau, Hirosumi, Hotamisligil, Kusminski, Lehrke, Li, Lin, McTernan, McTernan, Nancy F. da Silva, Pagano, Patel, Philip G. McTernan, Rae, Rajala, Rajala, Rangwala, Reilly, Ridker, Roeder, Sato, Savage, Shetty, Silswal, Steppan, Steppan, Steven J. Creely, Sudhesh Kumar, Tzou, Weisberg, Xu   +45 more
core   +1 more source

Preconditioning boosts regenerative programmes in the adult zebrafish heart [PDF]

Open Biology, 2016
During preconditioning, exposure to a non-lethal harmful stimulus triggers a body-wide increase of survival and pro-regenerative programmes that enable the organism to better withstand the deleterious effects of subsequent injuries.
Anne-Sophie de Preux Charles, Thomas Bise, Felix Baier, Pauline Sallin, Anna Jaźwińska   +4 more
doaj   +1 more source

Lactate Regulates Metabolic and Proinflammatory Circuits in Control of T Cell Migration and Effector Functions [PDF]

, 2015
Licensed by the Creative Commons Attribution ...
A Ene-Obong, A Lardner, AM Sidahmed, C Croia, C Gobelet, C Mauro, C Nathan, CH Chang, Claudio Mauro, Costantino Pitzalis, DK Finlay, DR Wahl, DW Jung, Elliot J. Bland, F Humby, F Vegran, Federica M. Marelli-Berg, Fulvio D’Acquisto, FW Fitch, G Yi, J Olloquequi, J Zhu, Joanne Smith, JR Doherty, K De Bock, K Fischer, KJ Livak, LZ Shi, M Buzzai, M Chabaud, M Kleinewietfeld, M Sukumar, Mauro Perretti, ME Morris, Michele Bombardieri, MJ Ovens, MM Delmastro-Greenwood, N Shyh-Chang, O Haworth, OR Colegio, Philippa Marrack, PP Hsu, R Haas, R Wang, RA Robergs, RD Michalek, Robert Haas, S Su, SJ Jarmin, SN Mueller, SP Young, SR Srinivas, SS Metkar, Suchita Nadkarni, T Hashimoto, T Hitosugi, T Montero-Melendez, T Soga, TC Leite, Trinidad Montero-Melendez, VA Gerriets, Vidalba Rocher-Ros, Y Cao   +62 more
core   +5 more sources

Bee Better: The Role of Honey in Modern Wound Care

Advanced Therapeutics, Volume 8, Issue 5, May 2025.
The use of honey as a wound care agent is controversial but paradoxically increasingly popular. Honey possesses relevant antimicrobial properties and can modulate the immune system. The wound healing properties of honey likely depend on its composition and varies across wound types.
Léo‐Paul Tricou, Natalie Guirguis, Sarah Djebbar, Benjamin R. Freedman, Simon Matoori   +4 more
wiley   +1 more source

Development of a Quantitative Assay for the Characterization of Human Collectin-11 (CL-11, CL-K1)

Frontiers in Immunology, 2018
Collectin-11 (CL-11) is a pattern recognition molecule of the lectin pathway of complement with diverse functions spanning from host defense to embryonic development.
Rafael Bayarri-Olmos, Nikolaj Kirketerp-Moller, Laura Pérez-Alós, Karsten Skjodt, Mikkel-Ole Skjoedt, Peter Garred   +5 more
doaj   +1 more source

Efficacy of Candida dubliniensis and Fungal β-Glucans in Inducing Trained Innate Immune Protection Against Inducers of Sepsis

Frontiers in Cellular and Infection Microbiology, 2022
Fungal-bacterial intra-abdominal infections (IAI) can lead to sepsis with significant morbidity and mortality. We have established a murine model of Candida albicans (Ca) and Staphylococcus aureus (Sa) IAI that results in acute lethal sepsis.
Amanda J. Harriett, Shannon Esher Righi, Elizabeth A. Lilly, Paul Fidel, Mairi C. Noverr   +4 more
doaj   +1 more source

Updates on Toll‐Like Receptor 10 Research

European Journal of Immunology, Volume 55, Issue 5, May 2025.
Toll‐like receptor 10 (TLR10 or CD290) shares the same structural organization as the other TLRs but shows a unique expression pattern and distinct functional activities yet to be fully elucidated. This review summarizes key steps and recent updates on TLR10 research including open questions and future perspectives.
Federica Riva, Marta Muzio
wiley   +1 more source