Results 11 to 20 of about 260,969 (247)

Hsa_circ_0088212-mediated miR-520 h/APOA1 axis inhibits osteosarcoma progression

Translational Oncology, 2021
Background: It has been known for decades that circRNAs are deregulated in cancer. Here, we characterized the role and underlying mechanism of circ_0088212 in osteosarcoma.
Feng Liu, Xiangyang Zhang, Fei Wu, Hao Peng   +3 more
doaj   +1 more source

Acquisition of the pulmonary venous and left atrial anatomy with non-contrast-enhanced MRI for catheter ablation of atrial fibrillation: Usefulness of two-dimensional balanced steady-state free precession

Journal of Arrhythmia, 2015
Background: Usually, the pulmonary venous and left atrial (PV–LA) anatomy is assessed with contrast-enhanced computed tomographic imaging for catheter ablation of atrial fibrillation (AF).
Yutaka Shigenaga, RT, Kunihiko Kiuchi, MD, Katsunori Okajima, MD, Kazushi Ikeuchi, RT, Takayuki Ikeda, RT, Akira Shimane, MD, Kiminobu Yokoi, MD, Jin Teranishi, MD, Kousuke Aoki, MD, Misato Chimura, MD, Hideyuki Masai, RT, Shinichiro Yamada, MD, Yasuyo Taniguchi, MD, Yoshinori Yasaka, MD, Hiroya Kawai, MD   +14 more
doaj   +1 more source

Swelling-Activated Cl− Current in Isolated Rabbit Articular Chondrocytes: Inhibition by Arachidonic Acid

Journal of Pharmacological Sciences, 2009
Articular chondrocytes play an important role in maintaining the structure and function of the cartilage in synovial joints, which is closely influenced by mechanical or osmotic stress.
Eiji Isoya, Futoshi Toyoda, Shinji Imai, Noriaki Okumura, Kousuke Kumagai, Mariko Omatsu-Kanbe, Mitsuhiko Kubo, Hiroshi Matsuura, Yoshitaka Matsusue   +8 more
doaj   +1 more source

Visualization of the radiofrequency lesion after pulmonary vein isolation using delayed enhancement magnetic resonance imaging fused with magnetic resonance angiography

Journal of Arrhythmia, 2015
Background: The radiofrequency (RF) lesions for atrial fibrillation (AF) ablation can be visualized by delayed enhancement magnetic resonance imaging (DE-MRI).
Kunihiko Kiuchi, MD, Katsunori Okajima, MD, Akira Shimane, MD, Kiminobu Yokoi, MD, Jin Teranishi, MD, Kousuke Aoki, MD, Misato Chimura, MD, Hideo Tsubata, MD, Taishi Miyata, MD, Yuuki Matsuoka, MD, Takayoshi Toba, MD, Shogo Ohishi, MD, Takahiro Sawada, MD, Yasue Tsukishiro, MD, Tetsuari Onishi, MD, Seiichi Kobayashi, MD, Shinichiro Yamada, MD, Yasuyo Taniguchi, MD, Yoshinori Yasaka, MD, Hiroya Kawai, MD, Kazushi Ikeuchi, RT, Yutaka Shigenaga, RT, Takayuki Ikeda, RT   +22 more
doaj   +1 more source

Impact of esophageal temperature monitoring guided atrial fibrillation ablation on preventing asymptomatic excessive transmural injury

Journal of Arrhythmia, 2016
Background: Even with the use of a reduced energy setting (20–25 W), excessive transmural injury (ETI) following catheter ablation of atrial fibrillation (AF) is reported to develop in 10% of patients.
Kunihiko Kiuchi, MD, FHRS, Katsunori Okajima, MD, Akira Shimane, MD, Gaku Kanda, MD, Kiminobu Yokoi, MD, Jin Teranishi, MD, Kousuke Aoki, MD, Misato Chimura, MD, Takayoshi Toba, MD, Shogo Oishi, MD, Takahiro Sawada, MD, Yasue Tsukishiro, MD, Tetsuari Onishi, MD, Seiichi Kobayashi, MD, Yasuyo Taniguchi, MD, Shinichiro Yamada, MD, Yoshinori Yasaka, MD, Hiroya Kawai, MD, Akihiro Yoshida, MD, Koji Fukuzawa, MD, Mitsuaki Itoh, MD, Kimitake Imamura, MD, Ryudo Fujiwara, MD, Atsushi Suzuki, MD, Tomoyuki Nakanishi, MD, Soichiro Yamashita, MD, Ken-ichi Hirata, MD, Hiroshi Tada, MD, FHRS, Hiro Yamasaki, MD, Yoshihisa Naruse, MD, Miyako Igarashi, MD, Kazutaka Aonuma, MD   +31 more
doaj   +1 more source

Localization of Thioredoxin-Interacting Protein in Aging and Alzheimer’s Disease Brains

NeuroSci, 2022
Thioredoxin-Interacting Protein (TXNIP) has been shown to have significant pathogenic roles in many human diseases, particularly those associated with diabetes and hyperglycemia. Its main mode of action is to sequester thioredoxins, resulting in enhanced
Haruka Tsubaki, Anarmaa Mendsaikhan, Undral Buyandelger, Ikuo Tooyama, Douglas G. Walker   +4 more
doaj   +1 more source

Visualizing radiofrequency lesions using delayed-enhancement magnetic resonance imaging in patients with atrial fibrillation: A modification of the method used by the University of Utah group

Journal of Arrhythmia, 2015
Background: Atrial tissue fibrosis has previously been identified using delayed-enhancement MRI (DE-MRI) in patients with atrial fibrillation (AF). Although the clinical importance of DE-MRI is well recognized, the visualization of atrial fibrosis and ...
Kunihiko Kiuchi, MD, Katsunori Okajima, MD, Akira Shimane, MD, Kiminobu Yokoi, MD, Jin Teranishi, MD, Kousuke Aoki, MD, Misato Chimura, MD, Hideo Tsubata, MD, Taishi Miyata, MD, Yuuki Matsuoka, MD, Takayoshi Toba, MD, Shogo Ohishi, MD, Takahiro Sawada, MD, Yasue Tsukishiro, MD, Tetsuari Onishi, MD, Seiichi Kobayashi, MD, Shinichiro Yamada, MD, Yasuyo Taniguchi, MD, Yoshinori Yasaka, MD, Hiroya Kawai, MD, Kazushi Ikeuchi, RT, Yutaka Shigenaga, RT, Takayuki Ikeda, RT   +22 more
doaj   +1 more source

A Study of Teenagers’ Awareness of Healthy Eating Patterns as a Precursor to Healthy Adulthood [PDF]

International Journal of Home Economics, Hospitality and Allied Research, 2022
The study investigated teenagers’ awareness of healthy eating patterns as a precursor to healthy adulthood in Ondo West Local Government Area of Ondo State, Nigeria, by employing a survey research design.
Cecilia A. Olarewaju, Monsurat Bello, Rachael F. Gbadebo   +2 more
doaj   +1 more source

Phosphatidylinositol4-phosphate 5-kinase prevents the decrease in the HERG potassium current induced by Gq protein-coupled receptor stimulation

Journal of Pharmacological Sciences, 2015
The human ether-a-go-go-related gene (HERG) potassium current (IHERG) has been shown to decrease in amplitude following stimulation with Gq protein-coupled receptors (GqRs), such as α1-adrenergic and M1-muscarinic receptors (α1R and M1R, respectively ...
Taeko Kubo, Wei-Guang Ding, Futoshi Toyoda, Yusuke Fujii, Mariko Omatsu-Kanbe, Hiroshi Matsuura   +5 more
doaj   +1 more source

Improved Manufacturability and In Vivo Comparative Pharmacokinetics of Dapagliflozin Cocrystals in Beagle Dogs and Human Volunteers

Pharmaceutics, 2021
Dapagliflozin (DAP), which improves glycemic control in patients with type 2 diabetes mellitus, has poor physical properties against heat and moisture, thus hindering its manufacturing potential.
Sangho Cho, Jeongwook Lee, Yongwon Yoo, Minyong Cho, Seil Sohn, Beom-Jin Lee   +5 more
doaj   +1 more source