Results 11 to 20 of about 337,494 (292)

Ascites

open access: yesThe Korean Journal of Gastroenterology, 2018
Ascites is the most common cause of decompensation in cirrhosis, and 5% to 10% of patients with compensated cirrhosis develop ascites each year. The main factor of ascites formation is renal sodium retention due to activation of the renin-angiotensin ...
Soung Won Jeong
doaj   +3 more sources

Ascites, refractory ascites and hyponatremia in cirrhosis [PDF]

open access: yesGastroenterology Report, 2017
Ascites is the most common complication related to cirrhosis and is associated with increased morbidity and mortality. Ascites is a consequence of the loss of compensatory mechanisms to maintain the overall effective arterial blood volume due to worsening splanchnic arterial vasodilation as a result of clinically significant portal hypertension.
Brett E. Fortune, Andrés Cárdenas
openaire   +4 more sources

Single-cell analyses implicate ascites in remodeling the ecosystems of primary and metastatic tumors in ovarian cancer

open access: yesNature Cancer, 2023
Ovarian cancer (OC) is an aggressive gynecological tumor usually diagnosed with widespread metastases and ascites. Here, we depicted a single-cell landscape of the OC ecosystem with five tumor-relevant sites, including omentum metastasis and malignant ...
Xiaocui Zheng   +12 more
semanticscholar   +1 more source

Ascites and resistance to immune checkpoint inhibition in dMMR/MSI-H metastatic colorectal and gastric cancers

open access: yesJournal for ImmunoTherapy of Cancer, 2022
Background Despite unprecedented benefit from immune checkpoint inhibitors (ICIs) in patients with mismatch repair deficient (dMMR)/microsatellite instability high (MSI-H) advanced gastrointestinal cancers, a relevant proportion of patients shows primary
G. Fucà   +30 more
semanticscholar   +1 more source

SCD1/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells

open access: yesTheranostics, 2021
Rationale: Malignant ascites in peritoneal metastases is a lipid-enriched microenvironment and is frequently involved in the poor prognosis of epithelial ovarian cancer (EOC).
Y. Xuan   +8 more
semanticscholar   +1 more source

Malignant Ascites in Ovarian Cancer: Cellular, Acellular, and Biophysical Determinants of Molecular Characteristics and Therapy Response

open access: yesCancers, 2021
Simple Summary Accumulation of excess fluid in the abdomen typically indicates abnormal function or disease, such as cancer, in the underlying tissues. This accumulation of fluid, or ascites, occurs more frequently in patients with advanced-stage ovarian
Brittany P. Rickard   +13 more
semanticscholar   +1 more source

The untapped potential of ascites in ovarian cancer research and treatment

open access: yesBritish Journal of Cancer, 2020
The build-up of fluid in the peritoneal cavity—ascites—is a hallmark of ovarian cancer, the most lethal of all gynaecological malignancies. This remarkable fluid, which contains a variety of cellular and acellular components, is known to contribute to ...
C. Ford   +3 more
semanticscholar   +1 more source

Ascitic pseudouridine discriminates between hepatocarcinoma-derived ascites and cirrhotic ascites [PDF]

open access: yesClinical Chemistry, 1996
Abstract Various biochemical indexes discriminate neoplastic from nonneoplastic ascites. However, within the latter group, the distinction between cirrhotic ascites and ascites caused by hepatocarcinoma (HC) is usually based on liver biopsy or cytology.
CASTALDO, GIUSEPPE   +6 more
openaire   +6 more sources

Xiaozhang Tie Improves Intestinal Motility in Rats With Cirrhotic Ascites by Regulating the Stem Cell Factor/c-kit Pathway in Interstitial Cells of Cajal

open access: yesFrontiers in Pharmacology, 2020
We previously discovered that Xiaozhang Tie (XZT) was helpful for cirrhotic ascites, with obvious abdominal distention relief, suggesting that it may improve gastrointestinal (GI) motility.
Qiang Zhao   +7 more
semanticscholar   +1 more source

Tumor-promoting macrophages prevail in malignant ascites of advanced gastric cancer

open access: yesExperimental and Molecular Medicine, 2020
Gastric cancer (GC) patients develop malignant ascites as the disease progresses owing to peritoneal metastasis. GC patients with malignant ascites have a rapidly deteriorating clinical course with short survival following the onset of malignant ascites.
Hye Hyeon Eum   +11 more
semanticscholar   +1 more source

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