Results 11 to 20 of about 373,948 (350)

Factors associated with the response to postnatal dexamethasone use in very low birthweight infants: a nationwide cohort study

BMJ Paediatrics Open, 2023
Background Dexamethasone is widely used as a systemic corticosteroid to treat and prevent bronchopulmonary dysplasia (BPD) in preterm infants. We evaluated the current epidemiology of dexamethasone use to prevent BPD and analyse the factors associated ...
Soon Min Lee, Min Soo Park, So Jin Yoon, In Gyu Song, Seung Hwan Baek, Jeong Eun Shin, Jungho Han, Joonsik Park, Su Min Lee, Sungbo Shim, Ho Seon Eun, Joohee Lim, Wook Chang   +12 more
doaj   +1 more source

Efficiency of a dexamethasone nanosuspension as an intratympanic injection for acute hearing loss

Drug Delivery, 2022
Dexamethasone sodium phosphate (Dex-SP) is the most commonly used drug administered via intratympanic injection for the treatment of acute hearing loss, but its penetration efficiency into the inner ear is very low.
So-Young Jung, Subin Kim, Zion Kang, Soonmin Kwon, Juhye Lee, Joo Won Park, Kab Sig Kim, Dong-Kee Kim   +7 more
doaj   +1 more source

The effect of dilution with glucose and prolonged injection time on dexamethasone-induced perineal irritation – A randomized controlled trial

Open Medicine, 2022
Dexamethasone can be used to prevent nausea and vomiting after surgery, but there is concern that it may induced perineal irritation. The aim of this study was to investigate the attenuation effect of dilution and slow injection on dexamethasone-induced ...
Zhang Yonghai, Liang Hong, Huang Liwei, Zheng Junwei, Chen Yi, Li Bin, Yang Fan, Yu Jingfang, Ma Hanxiang   +8 more
doaj   +1 more source

Dexamethasone Improves Cardiovascular Outcomes in Critically Ill COVID-19, a Real World Scenario Multicenter Analysis

Frontiers in Medicine, 2022
BackgroundSevere COVID-19 pneumonia requiring intensive care treatment remains a clinical challenge to date. Dexamethasone was reported as a promising treatment option, leading to a reduction of mortality rates in severe COVID-19 disease.
Peter Jirak, Vincent van Almsick, Dimitrios Dimitroulis, Moritz Mirna, Clemens Seelmaier, Zornitsa Shomanova, Bernhard Wernly, Bernhard Wernly, Bernhard Wernly, Dilvin Semo, Daniel Dankl, Magdalena Mahringer, Michael Lichtenauer, Uta C. Hoppe, Holger Reinecke, Rudin Pistulli, Robert Larbig, Robert Larbig, Lukas J. Motloch   +18 more
doaj   +1 more source

The Efficacy of High-Dose Dexamethasone vs. Other Treatments for Newly Diagnosed Immune Thrombocytopenia: A Meta-Analysis

Frontiers in Medicine, 2021
Objective: To compare the therapeutic efficacies of high dose dexamethasone, prednisone and rituximab in combination with dexamethasone for newly diagnosed ITP (Immune Thrombocytopenia, ITP) patients.Methods and results: Relevant publications for this ...
Qirong Xiao, Qirong Xiao, Bicun Lin, Bicun Lin, Hanyu Wang, Weiwu Zhan, Weiwu Zhan, Ping Chen, Ping Chen   +8 more
doaj   +1 more source

The Effect of Dexamethasone Treatment on COVID-19 Prognosis in Cancer Patients

Vaccines, 2022
Background: Dexamethasone is used to treat cancer, relieve chemotherapy-induced nausea and vomiting, enhance cancer patients’ appetites, and treat COVID-19 patients. There is little evidence of the impact of a dexamethasone treatment plan on the severity
Lina Souan, Zienab Al-Khairy, Maysaa’ Adnan Al-Binni, Abdelkader Battah, Maher A. Sughayer   +4 more
doaj   +1 more source

Dexamethasone and Dexamethasone Phosphate: Effect on DMPC Membrane Models

Pharmaceutics, 2023
Dexamethasone (Dex) and Dexamethasone phosphate (Dex-P) are synthetic glucocorticoids with high anti-inflammatory and immunosuppressive actions that gained visibility because they reduce the mortality in critical patients with COVID-19 connected to assisted breathing.
Candelaria Ines Cámara, Matías Ariel Crosio, Ana Valeria Juarez, Natalia Wilke   +3 more
openaire   +4 more sources

Immune and ionic mechanisms mediating the effect of dexamethasone in severe COVID-19

Frontiers in Immunology, 2023
IntroductionSevere COVID-19 is characterized by cytokine storm, an excessive production of proinflammatory cytokines that contributes to acute lung damage and death.
Ameet A. Chimote, Abdulaziz O. Alshwimi, Martina Chirra, Vaibhavkumar S. Gawali, Margaret V. Powers-Fletcher, Kristin M. Hudock, Kristin M. Hudock, Laura Conforti   +7 more
doaj   +1 more source

Analysis of renal impairment in MM-003, a phase III study of pomalidomide + low - dose dexamethasone versus high - dose dexamethasone in refractory or relapsed and refractory multiple myeloma

Haematologica, 2016
Pomalidomide + low-dose dexamethasone is effective and well tolerated for refractory or relapsed and refractory multiple myeloma after bortezomib and lenalidomide failure.
Katja C. Weisel, Meletios A. Dimopoulos, Philippe Moreau, Martha Q. Lacy, Kevin W. Song, Michel Delforge, Lionel Karlin, Hartmut Goldschmidt, Anne Banos, Albert Oriol, Adrian Alegre, Christine Chen, Michele Cavo, Laurent Garderet, Valentina Ivanova, Joaquin Martinez-Lopez, Stefan Knop, Xin Yu, Kevin Hong, Lars Sternas, Christian Jacques, Mohamed H. Zaki, Jesus San Miguel   +22 more
doaj   +1 more source

Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells [PDF]

, 2015
BACKGROUND: Dexamethasone suppressed inflammation and haemodynamic changes in an animal model of pulmonary arterial hypertension (PAH). A major target for dexamethasone actions is NF-κB, which is activated in pulmonary vascular cells and perivascular ...
Adcock, IM, Dorfmuller, P, Garfield, BE, Humbert, M, Meng, C, Montani, D, Perros, F, Price, LC, Shao, D, Wort, SJ, Zhu, J   +10 more
core   +2 more sources