Results 11 to 20 of about 517,435 (235)

Expanding the deep-learning model to diagnosis LVNC: Limitations and trade-offs [PDF]

Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization. 2024, 2023
Hyper-trabeculation or non-compaction in the left ventricle of the myocardium (LVNC) is a recently classified form of cardiomyopathy. Several methods have been proposed to quantify the trabeculae accurately in the left ventricle, but there is no general agreement in the medical community to use a particular approach.
arxiv   +1 more source

Understanding the genetics of adult-onset dilated cardiomyopathy: what a clinician needs to know.

European Heart Journal, 2021
There is increasing understanding of the genetic basis to dilated cardiomyopathy and in this review, we offer a practical primer for the practising clinician.
U. Tayal, J. Ware, N. Lakdawala, S. Heymans, S. Prasad   +4 more
semanticscholar   +1 more source

NON ISCHEMIC CARDIOMYOPATHY – A CASE REPORT

Liaquat Medical Research Journal, 2023
Cardiomyopathies are a group of diseases characterized by the structural and functional abnormalities of the heart muscles in the absence of other illnesses that might be responsible for the observed myocardial anomaly.
Anny Ashiq Ali Anny Ashiq Ali, Saba Muhammad Nazim   +1 more
doaj   +1 more source

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy

Nature Communications, 2020
Dilated cardiomyopathy (DCM) is an important cause of heart failure and the leading indication for heart transplantation. Many rare genetic variants have been associated with DCM, but common variant studies of the disease have yielded few associated loci.
J. Pirruccello, A. Bick, Minxian Wang, M. Chaffin, S. Friedman, Jie Yao, Xiuqing Guo, B. Venkatesh, K. Taylor, W. Post, S. Rich, J. Lima, J. Rotter, A. Philippakis, S. Lubitz, P. Ellinor, A. Khera, S. Kathiresan, K. Aragam   +18 more
semanticscholar   +1 more source

Mitochondrial Function and Dysfunction in Dilated Cardiomyopathy

Frontiers in Cell and Developmental Biology, 2021
Cardiac tissue requires a persistent production of energy in order to exert its pumping function. Therefore, the maintenance of this function relies on mitochondria that represent the “powerhouse” of all cardiac activities.
Daniela Ramaccini, Vanessa Montoya-Uribe, F. Aan, Lorenzo Modesti, Y. Potes, M. Wieckowski, I. Krga, M. Glibetić, P. Pinton, C. Giorgi, M. Matter   +10 more
semanticscholar   +1 more source

Reevaluating the Genetic Contribution of Monogenic Dilated Cardiomyopathy

Circulation, 2020
Supplemental Digital Content is available in the text. Background: Dilated cardiomyopathy (DCM) is genetically heterogeneous, with >100 purported disease genes tested in clinical laboratories.
F. Mazzarotto, U. Tayal, R. Buchan, W. Midwinter, Alicja E Wilk, N. Whiffin, R. Govind, Erica Mazaika, A. de Marvao, T. Dawes, L. Felkin, Mian Ahmad, P. Theotokis, Elizabeth C. Edwards, Alexander Y. Ing, K. Thomson, L. Chan, D. Sim, A. Baksi, A. Pantazis, Angharad M. Roberts, H. Watkins, B. Funke, D. O’Regan, I. Olivotto, P. J. Barton, Sanjay K. Prasad, S. Cook, J. Ware, R. Walsh   +29 more
semanticscholar   +1 more source

An Evidence-based Assessment of Genes in Dilated Cardiomyopathy

medRxiv, 2020
Background: The cardiomyopathies are classically categorized as hypertrophic (HCM), dilated (DCM), and arrhythmogenic right ventricular (ARVC), and each have a signature genetic theme.
Elizabeth Jordan, Laiken Peterson, Tomohiko Ai, B. Asatryan, Lucas M. Bronicki, E. Brown, R. Celeghin, M. Edwards, J. Fan, J. Ingles, C. James, O. Jarinova, Renee Johnson, D. Judge, N. Lahrouchi, Ronald H. Lekanne Deprez, R. Lumbers, F. Mazzarotto, A. M. Domingo, Rebecca L. Miller, A. Morales, B. Murray, S. Peters, K. Pilichou, A. Protonotarios, C. Semsarian, P. Shah, P. Syrris, C. Thaxton, J. V. van Tintelen, R. Walsh, Jessica J Wang, J. Ware, R. E. Hershberger   +33 more
semanticscholar   +1 more source

Dilated cardiomyopathy

Nature Reviews Disease Primers, 2019
Dilated cardiomyopathy (DCM) is a clinical diagnosis characterized by left ventricular or biventricular dilation and impaired contraction that is not explained by abnormal loading conditions (for example, hypertension and valvular heart disease) or ...
H. Schultheiss, D. Fairweather, A. Caforio, F. Escher, R. Hershberger, S. Lipshultz, Peter P. Liu, A. Matsumori, A. Mazzanti, J. Mcmurray, S. Priori   +10 more
semanticscholar   +2 more sources

The Effect of Type 2 Diabetes Mellitus on the Prognosis of Patients with Dilated Cardiomyopathy [PDF]

Zhongguo quanke yixue, 2023
Background Type 2 diabetes mellitus increases the risk of early onset of cardiovascular disease in patients, which poses a major threat to human health. Exploring the impact of type 2 diabetes mellitus on prognosis of patients with dilated cardiomyopathy
WANG Haiyan, HUANG Yuan, GUI Chun
doaj   +1 more source

BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy

Protein & Cell, 2020
Dysregulation of circadian rhythms associates with cardiovascular disorders. It is known that deletion of the core circadian gene Bmal1 in mice causes dilated cardiomyopathy.
Ermin Li, Xiuya Li, Jie Huang, Chen Xu, Qianqian Liang, Kehan Ren, Aobing Bai, Chao Lu, R. Qian, N. Sun   +9 more
semanticscholar   +1 more source