Results 11 to 20 of about 560,370 (324)
Food allergy immunotherapy: Oral immunotherapy and epicutaneous immunotherapy [PDF]
Allergy, 2020 AbstractIgE‐mediated food allergy remains a significant and growing problem across the globe. Of the various treatment modalities, oral immunotherapy (OIT) and epicutaneous immunotherapy (EPIT) have been the best studied. Across various studies of OIT for egg, milk, and peanut allergy, strong levels of desensitization have been shown.
Edwin H. Kim, Arvil Wesley Burks
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Immunotherapy of aspergillosis [PDF]
Clinical Microbiology and Infection, 2012 Management of invasive aspergillosis in high-risk patients remains challenging. There is an increasing demand for novel therapeutic strategies aimed at enhancing or restoring antifungal immunity in immunocompromised patients. In this regard, modulation of specific innate immune functions and vaccination are promising immunotherapeutic strategies ...
Cristina Cunha +4 more
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Immunotherapy for neurodegeneration? [PDF]
Science, 2019 The role of innate and adaptive immunity in neurodegeneration remains ...
Liu, Yingjun, Aguzzi, Adriano
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OncoImmunology, 2023 Previous studies have shown that local delivery of tumor antigen-specific CD8+ T lymphocytes engineered to transiently express single-chain IL-12 mRNA is highly efficacious.
Claudia Augusta Di Trani +16 more
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Molecular MRI-Based Monitoring of Cancer Immunotherapy Treatment Response [PDF]
Int. J. Mol. Sci. 2023, 24, 3151, 2023 Immunotherapy constitutes a paradigm shift in cancer treatment. Its FDA approval for several indications has yielded improved prognosis for cases where traditional therapy has shown limited efficiencey. However, many patients still fail to benefit from this treatment modality, and the exact mechanisms responsible for tumor response are unknown ...
arxiv +1 more source
CAR T cell therapy becomes CHIC: “cytokine help intensified CAR” T cells
Frontiers in Immunology, 2023 Chimeric antigen receptors (CARs) in the canonical “second generation” format provide two signals for inducing T cell effector functions; the primary “signal-1” is provided through the TCR CD3ζ chain and the “signal-2” through a linked costimulatory ...
Simone Thomas +3 more
doaj +1 more source
Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors
Science, 2018 Good bacteria help fight cancer Resident gut bacteria can affect patient responses to cancer immunotherapy (see the Perspective by Jobin). Routy et al. show that antibiotic consumption is associated with poor response to immunotherapeutic PD-1 blockade ...
B. Routy +47 more
semanticscholar +1 more source
Advances in immunotherapy for triple-negative breast cancer
Molecular Cancer, 2023 Background Immunotherapy has recently emerged as a treatment strategy which stimulates the human immune system to kill tumor cells. Tumor immunotherapy is based on immune editing, which enhances the antigenicity of tumor cells and increases the ...
Yang Liu +8 more
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Intralymphatic immunotherapy [PDF]
World Allergy Organization Journal, 2015 Gold Standard allergen-specific immunotherapy is associated with low efficacy because it requires either many subcutaneous injections of allergen or even more numerous sublingual allergen administrations to achieve amelioration of symptoms. Intralymphatic vaccination can maximize immunogenicity and hence efficacy.
Gabriela Senti, Thomas M Kündig
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Cancer immunotherapy using checkpoint blockade
Science, 2018 The release of negative regulators of immune activation (immune checkpoints) that limit antitumor responses has resulted in unprecedented rates of long-lasting tumor responses in patients with a variety of cancers.
A. Ribas, J. Wolchok
semanticscholar +1 more source