Association between weight-adjusted waist index and carotid atherosclerotic plaque in patients with type 2 diabetes in the Chinese population [PDF]
Diabetology & Metabolic SyndromePurpose The purpose of this study is to investigate the relationship between the weight-adjusted waist index (WWI) and the incidence of carotid atherosclerotic plaque in patients with type 2 diabetes (T2DM) in the Chinese population.
Yu Qin +7 more
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Advanced Detection and Therapeutic Monitoring of Atherosclerotic Plaque Using CD36-Targeted Lipid Core Probe [PDF]
PharmaceuticsBackground: Atherosclerotic diseases, including coronary heart disease and cerebrovascular disease, are leading causes of morbidity and mortality worldwide. Atherosclerosis is a chronic vascular condition marked by the accumulation of lipid plaque within
Tingting Gao +9 more
doaj +2 more sources
Macrophage anti-inflammatory behaviour in a multiphase model of atherosclerotic plaque development [PDF]
Bull Math Biol 85, 37 (2023), 2022 Atherosclerosis is an inflammatory disease characterised by the formation of plaques, which are deposits of lipids and cholesterol-laden macrophages that form in the artery wall. The inflammation is often non-resolving, due in large part to changes in normal macrophage anti-inflammatory behaviour that are induced by the toxic plaque microenvironment ...
arxiv +1 more source
Cell Death and Disease, 2021 Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has been proved to ...
Jin-Ling Ren +9 more
doaj +1 more source
Research Progress on the Risk Factors and Outcomes of Human Carotid Atherosclerotic Plaques
Chinese Medical Journal, 2017 Objective: Atherosclerosis is an inflammatory process that results in complex lesions or plaques that protrude into the arterial lumen. Carotid atherosclerotic plaque rupture, with distal atheromatous debris embolization, causes cerebrovascular events ...
Xiang-Dong Xiong +3 more
doaj +1 more source
The Role of Matrix Metalloproteinase-9 in Atherosclerotic Plaque Instability
Mediators of Inflammation, 2020 Matrix metalloproteinase-9 (MMP-9) belongs to the MMP family and has been widely investigated. Excessive MMP-9 expression can enhance extracellular matrix degradation and promote plaque instability.
Tiewei Li +5 more
doaj +1 more source
HDL and plaque regression in a multiphase model of early atherosclerosis [PDF]
, 2023 Atherosclerotic plaques are accumulations of cholesterol-engorged macrophages in the artery wall. Plaque growth is initiated and sustained by the deposition of low density lipoproteins (LDL) in the artery wall. High density lipoproteins (HDL) counterbalance the effects of LDL by accepting cholesterol from macrophages and removing it from the plaque. In
arxiv +1 more source
Frontiers in Neurology, 2023 Atherosclerosis is an important cause of cerebrovascular and cardiovascular disease (CVD). Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation.
Zhiwei He +6 more
doaj +1 more source
Towards parallel time-stepping for the numerical simulation of atherosclerotic plaque growth [PDF]
, 2022 The numerical simulation of atherosclerotic plaque growth is computationally prohibitive, since it involves a complex cardiovascular fluid-structure interaction (FSI) problem with a characteristic time scale of milliseconds to seconds, as well as a plaque growth process governed by reaction-diffusion equations, which takes place over several months. In
arxiv +1 more source
Oral glucose tolerance test predicts increased carotid plaque burden in patients with acute coronary syndrome. [PDF]
PLoS ONE, 2017 Type 2 diabetes and prediabetes are established risk factors for atherosclerosis. The aim of this study was to evaluate the atherosclerotic plaque burden in the carotid arteries of patients with acute coronary syndrome according to their glycemic status ...
Thorarinn A Bjarnason +7 more
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