LncRNAs as Regulators of Atherosclerotic Plaque Stability [PDF]
Cells, 2023 Current clinical data show that, despite constant efforts to develop novel therapies and clinical approaches, atherosclerotic cardiovascular diseases (ASCVD) are still one of the leading causes of death worldwide.
Aleksa Petkovic +10 more
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Gut Microbiota and Atherosclerosis—Focusing on the Plaque Stability [PDF]
Frontiers in Cardiovascular Medicine, 2021 Cardiovascular diseases (CVDs) are major causes of mortality and morbidity in the modern society. The rupture of atherosclerotic plaque can induce thrombus formation, which is the main cause of acute cardiovascular events.
Xinyi Shen +6 more
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The Role of Hydrogen Sulfide in Plaque Stability [PDF]
Antioxidants, 2022 Atherosclerosis is the greatest contributor to cardiovascular events and is involved in the majority of deaths worldwide. Plaque rapture or erosion precipitates life-threatening thrombi, resulting in the obstruction blood flow to the heart (acute ...
Qian Lin, Bin Geng
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Retrospective study on the association between carotid plaque stability assessed by ultrasound imaging features and stroke risk [PDF]
Frontiers in NeurologyBackgroundCarotid plaque instability is a critical determinant of ischemic stroke risk. Identifying ultrasound imaging features associated with plaque vulnerability may enhance stroke risk stratification.MethodsThis retrospective cohort study evaluated ...
Bo Wang, Yingjun Li, LiSha Qiu
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Exosomal circSCMH1/miR-874 ratio in serum to predict carotid and coronary plaque stability [PDF]
Frontiers in Cardiovascular Medicine, 2023 BackgroundTo investigate the correlation between lg (circSCMH1/miR-874) and acute coronary syndrome (ACS), acute myocardial infarction (AMI), and carotid plaque stability.Methods701 patients were divided into stable coronary artery disease (SCAD), ACS ...
Jiayu Wang +8 more
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Protein lactylation influences atherosclerotic plaque stability by regulating macrophage functions [PDF]
Frontiers in ImmunologyAtherosclerosis (AS) is a leading cause of cardiovascular events and mortality worldwide. Plaque stability is a direct determinant of clinical outcomes for patients.
Wenyan Liu +5 more
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The “angiogenesis-plaque stability paradox” in atherosclerosis pathogenesis [PDF]
Frontiers in Cardiovascular MedicineIntraplaque angiogenesis, a critical mechanism in the pathological progression of atherosclerosis (AS), exhibits a paradoxical role by providing nutrients and repair support for plaques while simultaneously contributing to plaque instability and rupture.
Fei Yan, Si-yang Sun, Hong Wu
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Ceramide as a key regulatory factor in the impact of dietary inflammatory index on plaque stability [PDF]
Scientific ReportsDiet influences plaque stability through its potential to modulate inflammation, a process that involves complex interactions among various lipid metabolites.
Zhenjuan Zhao +12 more
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Frontiers in Neurology, 2022 BackgroundCarotid atherosclerosis, especially the rupture of unstable plaques, plays an important role in the development of stroke. A novel lipid ratio, the non-high-density lipoprotein cholesterol (non-HDL-C)/high-density lipoprotein cholesterol (HDL-C)
Anran Wang +13 more
doaj +3 more sources
Potential new therapeutic targets: Association of microRNA with atherosclerotic plaque stability [PDF]
International Journal of Immunopathology and Pharmacology, 2023 Cardiovascular disease represents a major threat to human health with vascular atherosclerosis contributing significantly to its cause, particularly due to the ease of rupture of atherosclerotic plaques.
Pan Huang
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