Results 31 to 40 of about 78,612 (185)

Atherosclerotic plaque rupture – pathologic basis of plaque stability and instability [PDF]

Cardiovascular Research, 1999
Time for primary reveiw 27 days Atherosclerosis continues to be one of the main subjects in pathology research. The intriguing complexity of its pathogenesis as well as the importance of its clinical sequelae provide a rationale for this [1]. A large number of diseases with totally different clinical presentations are basically atherosclerosis ...
A C, van der Wal, A E, Becker
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Clinical Utility of the Serum Level of Lipoprotein-Related Phospholipase A2 in Acute Ischemic Stroke With Cerebral Artery Stenosis

Frontiers in Neurology, 2021
We aimed to study the clinical utility of serum lipoprotein-associated phospholipase A2 (Lp-PLA2) in acute ischemic stroke (AIS) with cerebral artery stenosis (CAS). We included 200 AIS patients and 90 healthy controls in this study.
Jing Cao, Ping Yan, Yajun Zhou, Xia Zhou, Zhongwu Sun, Xiao-Qun Zhu   +5 more
doaj   +1 more source

Neutrophil-specific STAT4 deficiency attenuates atherosclerotic burden and improves plaque stability via reduction in neutrophil activation and recruitment into aortas of Ldlr−/− mice

Frontiers in Cardiovascular Medicine, 2023
Background and aimsNeutrophils drive atheroprogression and directly contribute to plaque instability. We recently identified signal transducer and activator of transcription 4 (STAT4) as a critical component for bacterial host defense in neutrophils. The
W. Coles Keeter, Alina K. Moriarty, Alina K. Moriarty, Rachel Akers, Rachel Akers, Shelby Ma, Marion Mussbacher, Marion Mussbacher, Jerry L. Nadler, Elena V. Galkina, Elena V. Galkina   +10 more
doaj   +1 more source

Ultra-short echo time cardiovascular magnetic resonance of atherosclerotic carotid plaque [PDF]

, 2010
Background Multi-contrast weighted cardiovascular magnetic resonance (CMR) allows detailed plaque characterisation and assessment of plaque vulnerability.
Sonia Nielles-Vallespin, Nielles-Vallespin, S, Firmin, DN, Chan, Cheuk F, Keenan, Niall G, Mary N Sheppard, Gatehouse, Peter, Chan Cheuk F, Firmin David N, Gatehouse, P, Keenan, NG, Sheppard, MN, Boyle, JJ, Peter Gatehouse, Chan, CF, Sheppard Mary N, Boyle Joseph J, Joseph J Boyle, Niall G Keenan, Nielles-Vallespin, Sonia, Boyle, Joseph J, Sheppard, Mary N, Pennell, Dudley J, Pennell, DJ, Pennell Dudley J, Gatehouse Peter, Dudley J Pennell, Nielles-Vallespin Sonia, David N Firmin, Cheuk F Chan, Keenan Niall G, Firmin, David N   +31 more
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Flow Cytometry-Based Characterization of Mast Cells in Human Atherosclerosis

Cells, 2019
The presence of mast cells in human atherosclerotic plaques has been associated with adverse cardiovascular events. Mast cell activation, through the classical antigen sensitized-IgE binding to their characteristic Fcε-receptor, causes the release ...
Eva Kritikou, Marie A.C. Depuydt, Margreet R. de Vries, Kevin E. Mulder, Arthur M. Govaert, Marrit D. Smit, Janine van Duijn, Amanda C. Foks, Anouk Wezel, Harm J. Smeets, Bram Slütter, Paul H.A. Quax, Johan Kuiper, Ilze Bot   +13 more
doaj   +1 more source

Plaque stability and plaque regression: new insights [PDF]

European Heart Journal Supplements, 2006
Patients with prior cardiovascular disease and/or diabetes are at the highest risk of a myocardial infarction or stroke. Thus, the majority of morbid cardiovascular events arise in the large population of patients with qualifying risk factors, according to standard risk factor scoring techniques.
Diethelm Tschoepe, Bernd Stratmann
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High Zn content of Randall's plaque: A μ-X-ray fluorescence investigation [PDF]

, 2011
Kidney stone disease, or nephrolithiasis, is a common ailment. Among the different risk factors usually associated with nephrolithiasis are dehydration, metabolic defects (especially with regard to calcium and oxalate).
Dominique Bazin, Christelle Combes, Combes, Christèle, Bazin, Dominique, Michel Daudon, Aurélie Mazouyes, Daudon, Michel, Mazouyes, Aurélie, Xavier Carpentier, Rouzière, Stephan, Stephan Rouzière, Eddy Foy, Carpentier, Xavier, Pierre Antoine Albouy, Foy, Eddy, Albouy, Pierre-Antoine   +15 more
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Klotho protects against chronic kidney disease-associated atherosclerotic plaque vulnerability in

Di-san junyi daxue xuebao, 2020
Objective To explore the effects of chronic kidney disease (CKD) on the instability of atherosclerotic plaques and investigate the role of Klotho in this pathological process.
BI Xianjin, YANG Jiangxin, XIONG Jiachuan, YANG Ke, ZHAO Jinghong   +4 more
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Low adiponectin levels are an independent predictor of mixed and non-calcified coronary atherosclerotic plaques. [PDF]

, 2009
Atherosclerosis is the primary cause of coronary artery disease (CAD). There is increasing recognition that lesion composition rather than size determines the acute complications of atherosclerotic disease.
Lebherz Corinna, Renee Stark, Christoph Becker, Stark, R.G., Stark, Renee, Tittus, Janine, Lehrke Michael, Lebherz, C., Greif, Martin, Greif Martin, Broedl Uli C., Reiser, M., Stark Renee, Reiser, Maximilian, Ziegler, Franz von, Alexander W Leber, Göke, B., Parhofer, K.G., Lebherz, Corinna, Alexander Becker, Leber, A.W., Leber, Alexander W., Michael Lehrke, Corinna Lebherz, Lehrke, Michael, Greif, M., von Ziegler Franz, Parhofer Klaus G., von Ziegler, A., Göke, Burkhard, Parhofer, Klaus G., Janine Tittus, Becker, C., Becker Alexander, Broedl, U.C., Reiser Maximilian, Broedl, Uli C., Martin Greif, Klaus G Parhofer, Tittus, J., Tittus Janine, Burkhard Göke, Göke Burkhard, Becker, F., Becker, Alexander, Maximilian Reiser, Uli C Broedl, Becker, Christoph, Becker Christoph, Leber Alexander W., Franz von Ziegler, Lehrke, M.   +51 more
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How to stabilize unstable plaque [PDF]

Cardiovascular Research, 2011
This editorial refers to ‘Inhibition of rupture of established atherosclerotic plaques by treatment with apolipoprotein A-I’ by G.J. Reimers et al. , doi:10.1093/cvr/cvr057 Association studies and epidemiological observations have shown that high plasma levels of high-density lipoprotein-cholesterol (HDL-C) provide cardiovascular protection.1 The ...
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