Results 11 to 20 of about 78,612 (185)

Transforming growth factor-β2 is associated with atherosclerotic plaque stability and lower risk for cardiovascular events [PDF]

Cardiovascular Research, 2023
AIMS: Transforming growth factor-beta (TGF-β) exists in three isoforms TGF-β1, -β2 and -β3. TGF-β1 has been suggested to be important for maintaining plaque stability, yet the role of TGF-β2 and -β3 in atherosclerosis remains to be investigated ...
Andreas Edsfeldt, Frank Matthes, Pontus Dunér   +2 more
exaly   +5 more sources

Biomechanical factors and macrophages in plaque stability [PDF]

Cardiovascular Research, 2013
Thin-cap fibroatheromas (TCFAs) or vulnerable atherosclerotic plaques are considered a high-risk phenotype for acute cardiovascular events. TCFAs are identified by a thin rupture-prone fibrous cap, a large necrotic core, and a high content of leucocytes. Atherogenesis is dependent upon complex patterns of blood flow.
Seneviratne, A, Hulsmans, M, Holvoet, P, Monaco, C   +3 more
openaire   +3 more sources

Individuality, Stability, and Variability of the Plaque Microbiome [PDF]

Frontiers in Microbiology, 2016
Dental plaque is a bacterial biofilm composed of a characteristic set of organisms. Relatively little information from cultivation-independent, high-throughput analyses has been published on the temporal dynamics of the dental plaque microbiome. We used Minimum Entropy Decomposition, an information theory-based approach similar to oligotyping that ...
Daniel R. Utter, Daniel R. Utter, Jessica L. Mark Welch, Jessica L. Mark Welch, Gary G. Borisy   +4 more
core   +8 more sources

Distribution characteristics of coronary atherosclerotic plaque in patients with myocardial bridge of mid⁃left anterior descending coronary artery and influencing factors of plaque stability

Zhongguo linchuang yanjiu
Objective To explore the relationship between myocardial bridge（MB）parameters and plaque distribution in patients with coronary atherosclerosis，as well as the factors influencing plaque stability.
CHEN Zhenmin*，Li Yanping，HE Huiqiong，WU Xi
doaj   +2 more sources

The Value of Lp-PLA2 as a Biomarker for the Diagnosis of Plaque Stability in Atherosclerosis: A Meta-Analysis [PDF]

Clinical and Applied Thrombosis/Hemostasis
Background & Objective: Lipoprotein-associated phospholipase A2 (Lp-PLA2), secreted by inflammatory cells within atherosclerosis lesions, has emerged as a promising biomarker linked to plaque stability.
Ting Huang MS, Baocheng Zhu MS
doaj   +2 more sources

Inflammation-Related MicroRNAs Are Associated with Plaque Stability Calculated by IVUS in Coronary Heart Disease Patients

Journal of Interventional Cardiology, 2019
Objectives. This study aimed to investigate the association between inflammation-related microRNAs (miR-21, 146a, 155) and the plaque stability in coronary artery disease patients. Methods.
Guo-fu Zhu, Tianshu Chu, Zhimin Ruan, Mingguo Zhang, Mingli Zhou, Qian Zhang, Ran Zhang, Liyong Wu   +7 more
doaj   +2 more sources

Evaluation of Intensive Statins and Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors on Intracranial Artery Plaque Stability: A Prospective Single‐Arm Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Intracranial atherosclerotic stenosis is a leading cause of ischemic stroke and recurrent events due to plaque instability. High‐resolution magnetic resonance imaging identifies plaque enhancement as a key marker of instability.
Weiqi Zeng, Feng Zhou, Hai Zhao, Yukai Wang, Jingjuan Chen, Jiancong Lu, Dezhi Zheng, Jingyun Kuang, Dahua Yuan, Jing Zhou, Changzheng Shi, Xihai Zhao, Xinyi Leng, Bernard Yan, Zefeng Tan   +14 more
doaj   +3 more sources

Metformin Directly Binds to MMP-9 to Improve Plaque Stability. [PDF]

J Cardiovasc Dev Dis, 2023
Vulnerable atherosclerotic plaque rupture is the principal mechanism that accounts for myocardial infarction and stroke. High matrix metalloproteinase-9 (MMP-9) expression and activity have been proven to lead to plaque instability.
Chen X, Wang S, Xu W, Zhao M, Zhang Y, Xiao H.   +5 more
europepmc   +2 more sources

Hypercoagulability Impairs Plaque Stability in Diabetes-Induced Atherosclerosis. [PDF]

Nutrients, 2022
Diabetes mellitus, which is largely driven by nutritional and behavioral factors, is characterized by accelerated atherosclerosis with impaired plaque stability.
Ambreen S, Fatima S, Elwakiel A, Rana R, Singh K, Gupta A, Gupta D, Khawaja H, Manoharan J, Besler C, Laufs U, Kohli S, Isermann B, Shahzad K.   +13 more
europepmc   +2 more sources

A Switch from Cell-Associated to Soluble PDGF-B Protects against Atherosclerosis, despite Driving Extramedullary Hematopoiesis

Cells, 2021
Platelet-derived growth factor B (PDGF-B) is a mitogenic, migratory and survival factor. Cell-associated PDGF-B recruits stabilizing pericytes towards blood vessels through retention in extracellular matrix.
Renée J. H. A. Tillie, Thomas L. Theelen, Kim van Kuijk, Lieve Temmerman, Jenny de Bruijn, Marion Gijbels, Christer Betsholtz, Erik A. L. Biessen, Judith C. Sluimer   +8 more
doaj   +1 more source