Results 21 to 30 of about 78,612 (185)

Identification of a Novel Angiogenesis Signalling circSCRG1/miR-1268b/NR4A1 Pathway in Atherosclerosis and the Regulatory Effects of TMP-PF In Vitro

Molecules, 2023
Angiogenesis contributes to plaque instability in atherosclerosis and further increases cardio-cerebrovascular risk. Circular RNAs (circRNAs) are promising biomarkers and potential therapeutic targets for atherosclerosis.
Rong Yuan, Qiqi Xin, Xiaochang Ma, Meng Yu, Yu Miao, Keji Chen, Weihong Cong   +6 more
doaj   +1 more source

Macrophage death in atherosclerosis: potential role in calcification

Frontiers in Immunology, 2023
Cell death is an important aspect of atherosclerotic plaque development. Insufficient efferocytosis of death cells by phagocytic macrophages leads to the buildup of a necrotic core that impacts stability of the plaque.
Jaap G. Neels, Claire Gollentz, Giulia Chinetti   +2 more
doaj   +1 more source

Impact of Food Exposome on Atherosclerotic Plaque Stability: Metabolomic Insights from Human Carotid Endarterectomy Specimen. [PDF]

Int J Mol Sci
Carotid atherosclerotic stenosis (CAS) is a leading cause of ischemic stroke. Current understanding of plaque vulnerability remains largely confined to histopathological characterization.
Doche E, Leclercq B, Sulowski C, Magoncia E, Tardivel C, Svilar L, Sarlon-Bartoli G, Martin JC, Bartoli M, Rossillon A, Suissa L.   +10 more
europepmc   +2 more sources

Association Between Triglyceride–Glucose Index and Carotid Plaque Stability in Different Glycemic Status: A Single‐Center Retrospective Study [PDF]

Journal of the American Heart Association
Guijun Huo, Zhichao Yao, Yuqi Zeng
exaly   +2 more sources

Ginsenoside Rb1 Enhances Plaque Stability and Inhibits Adventitial Vasa Vasorum via the Modulation of miR-33 and PEDF

Frontiers in Cardiovascular Medicine, 2021
Background: Atherosclerosis is closely associated with proliferation of the adventitial vasa vasorum, leading to the atherosclerotic plaque progression and vulnerability.
Xiaoyan Yang, Xiaoyan Yang, Lei Wang, Zihao Zhang, Jiayi Hu, Xiaoling Liu, Hao Wen, Hao Wen, Minghao Liu, Minghao Liu, Xue Zhang, Xue Zhang, Hongyan Dai, Mei Ni, Rui Li, Rong Guo, Lei Zhang, Xiaorong Luan, Huili Lin, Mei Dong, Huixia Lu   +20 more
doaj   +1 more source

Chronic Stress A Potential Suspect Zero of Atherosclerosis: A Systematic Review

Frontiers in Cardiovascular Medicine, 2021
Atherosclerosis (AS) is a chronic vascular inflammatory disease, in which the lipid accumulation in the intima of the arteries shows yellow atheromatous appearance, which is the pathological basis of many diseases, such as coronary artery disease ...
Ling-bing Meng, Ling-bing Meng, Yuan-meng Zhang, Yue Luo, Tao Gong, De-ping Liu, De-ping Liu   +6 more
doaj   +1 more source

Stabilization of high-risk plaques [PDF]

Cardiovascular Diagnosis and Therapy, 2016
The prevalence of atherosclerotic cardiovascular diseases (ASCVDs) is increasing globally and they have become the leading cause of death in most countries. Numerous experimental and clinical studies have been conducted to identify major risk factors and effective control strategies for ASCVDs.
Kohei, Takata, Satoshi, Imaizumi, Bo, Zhang, Shin-Ichiro, Miura, Keijiro, Saku   +4 more
openaire   +2 more sources

miR-150-5p affects AS plaque with ASMC proliferation and migration by STAT1

Open Medicine, 2021
We explore miR‐150‐5p in atherosclerosis (AS). The AS model was constructed using Apo E−/− mice with an injection of the miR-150-5p mimic or an inhibitor.
Bian Yuan, Cai Wenqiang, Lu Hongying, Tang Shuhong, Yang Keqin, Tan Yan   +5 more
doaj   +1 more source

A New Paradigm for Plaque Stabilization [PDF]

Circulation, 2002
Abstract: The concept of plaque stabilization was developed to explain how lipid lowering could decrease adverse coronary events without a substantial reduction in the regression of atherosclerosis.
John A, Ambrose, Eulogio E, Martinez
openaire   +2 more sources

Stabilization of atherosclerotic plaques: an update [PDF]

European Heart Journal, 2013
The majority of coronary thrombi (∼75%) is caused by plaque rupture .1,2 Prototype of the rupture-prone plaque contains a large, soft, lipid-rich necrotic core with a thin and inflamed fibrous cap, so-called thin-cap fibroatheroma (TCFA) ( Figure 1 ).3,4 Other common features include expansive remodelling, large plaque size, plaque haemorrhage ...
Yla-Herttuala, S., Bentzon, J.F., Daemen, M., Falk, E., Garcia-Garcia, H.M., Herrmann, J., Hoefer, I., Jauhiainen, S., Jukema, J.W., Krams, R., Kwak, B.R., Marx, N., Naruszewicz, M., Newby, A., Pasterkamp, G., Serruys, P.W.J.C., Waltenberger, J., Weber, C., Tokgozoglu, L., ESC Working Grp Atherosclerosis Va   +19 more
openaire   +6 more sources