Results 11 to 20 of about 114,732 (196)

Pathogenesis of chronic obstructive pulmonary disease [PDF]

, 2005
The current paradigm for the pathogenesis of chronic obstructive pulmonary disease is that chronic airflow limitation results from an abnormal inflammatory response to inhaled particles and gases in the lung. Airspace inflammation appears to be different
Macnee, W
core   +2 more sources

Pulmonary interstitial emphysema in fatal asthma: case report and histopathological review

BMC Pulmonary Medicine, 2018
Background Mortality related to asthma has decreased worldwide since the introduction of inhaled corticosteroid therapy in the past decades. However, there are still some asthma fatalities identified mainly in populations with less access to regular ...
Thais Mauad, Felipe B. P. do Nascimento, Marisa Dolhnikoff, Milena C. M. Picka, Paulo H. N. Saldiva, on behalf of BIAS   +5 more
doaj   +1 more source

長期間喫煙による気管支唱息,肺気腫の病態的変化 [PDF]

, 2004
The influence of long-term cigarette smoking on the pathophysiology of chronic respiratory diseases with obstructive ventilatory dysfunction was discussed in patients with asthma and pulmonary emphysema (PE). 1.
Ashida, Kozo, Fujii, Makoto, Hamada, Masanori, Hosaki, Yasuhiro, Iwagaki, Naofumi, Mitsunobu, Fumihiro, Takata, Shingo, Tanizaki, Yoshiro   +7 more
core   +1 more source

Percutaneous evacuation of diffuse pulmonary interstitial emphysema by lung puncture in a baby with extremely low birth weight: a case report

Journal of Medical Case Reports, 2012
Introduction Pulmonary interstitial emphysema is a serious complication of mechanical ventilation and can become life-threatening if progression occurs. Therapeutic lung puncture is a treatment option for severe pulmonary interstitial emphysema but has a
Watanabe Masahiro, Momoi Nobuo, Sato Maki, Go Hayato, Imamura Takashi, Kaneko Masatoshi, Hosoya Mitsuaki   +6 more
doaj   +1 more source

Quantitative CT analysis in patients with pulmonary emphysema: is lung function influenced by concomitant unspecific pulmonary fibrosis? [PDF]

, 2019
Purpose: Quantitative analysis of CT scans has proven to be a reproducible technique, which might help to understand the pathophysiology of chronic obstructive pulmonary disease (COPD) and combined pulmonary fibrosis and emphysema.
Doellinger, Felix, Feldhaus, Felix W., Hubner, Ralf-Harto, Kuhnigk, Jan-Martin, Neumann, Konrad, Theilig, Dorothea Cornelia   +5 more
core   +1 more source

Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases. [PDF]

, 2016
BACKGROUND: Emphysema is characterised by distinct pathological sub-types, but little is known about the divergent underlying aetiology. Matrix-metalloproteinases (MMPs) are proteolytic enzymes that can degrade the extracellular matrix and have been ...
Bourne, S, Coombs, NA, Elkington, PT, Estepar, RS, Harden, S, Kim, V, Ostridge, K, Staples, KJ, Washko, G, Wilkinson, TM, Williams, N   +10 more
core   +1 more source

Chronic Pulmonary Emphysema

Postgraduate Medicine, 1956
Patients with chronic pulmonary emphysema were analyzed on clinical and morphological standpoints. Pulmonary function tests and selective alveolobronchography were used for this study. Significant differences in two types of clinical features of chronic pulmonary emphysema were demonstrated on one aspect, and remarkable overlapping of alveolar and ...
B, HYDE, L, HYDE
openaire   +6 more sources

The effect of PPE-induced emphysema and chronic LPS-induced pulmonary inflammation on atherosclerosis development in APOE*3-LEIDEN mice. [PDF]

PLoS ONE, 2013
BackgroundChronic obstructive pulmonary disease (COPD) is characterized by pulmonary inflammation, airways obstruction and emphysema, and is a risk factor for cardiovascular disease (CVD).
P Padmini S J Khedoe, Man C Wong, Gerry T M Wagenaar, Jaap J Plomp, Miranda van Eck, Louis M Havekes, Patrick C N Rensen, Pieter S Hiemstra, Jimmy F P Berbée   +8 more
doaj   +1 more source

Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression [PDF]

, 2010
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis, emphysema and irreversible airflow limitation. These changes are thought to be due to oxidative stress and an imbalance of proteases and antiproteases ...
A Babusyte, A Kode, A Papi, A Sebastian, A Sydbom, AP Rogerio, AW Boots, C Kandaswami, C Tabak, CJ Vlahos, D Nowak, DC Newcomb, EH Walker, G Agullo, GA Finlay, GW Peet, HJ Park, HS Deshmukh, HS Deshmukh, I Rahman, IC Walda, IK Demedts, J Robak, JA Conquer, JC Chen, JD Hasday, JH Vernooy, JW Hwang, K Ito, K Minamoto, K Ohnishi, KF Chung, KK Meja, L Biasutto, L Larsson, L Segura-Valdez, M Comalada, M Harwood, M Ichinose, M Kasielski, M Suzuki, MK Hwang, MM Mu, N Louhelainen, O Michel, P Maestrelli, P Santus, PC Hollman, PF Mercer, PJ Jagielo, R Mahadeva, S Nanua, S Rajendrasozhan, S Shishodia, SK Biswas, SP Davies, SV Culpitt, T Shinohara, T Zheng, U Sajjan, W MacNee, Y Kaneko, Y Nakamaru, Y-T Huang   +63 more
core   +6 more sources

Pulmonary Comorbidities of Lung Emphysema

대한영상의학회지, 2018
Pulmonary emphysema is defined as the “abnormal permanent enlargement of the airspaces distal to the terminal bronchioles accompanied by destruction of the alveolar wall and without obvious fibrosis.” Pulmonary emphysema could result in various ...
Hye Rim Park, Young Tong Kim, Sung Shick Jou, Chan Ho Park   +3 more
doaj   +1 more source