Results 11 to 20 of about 29,560 (219)

Molecular theranostics: principles, challenges and controversies [PDF]

Journal of Medical Radiation Sciences
Theranostics is a new term for long‐established principles in nuclear medicine. The generalisability of the term means there is a very broad use of the term across the medical literature, not all of which is consistent with the intent in nuclear medicine.
Geoffrey Currie
doaj   +2 more sources

Nano-Carbons as Theranostics [PDF]

Theranostics, 2012
Nano-carbons, including fullerenes, carbon nanoparticles, carbon nanotubes, graphene, and nano-diamonds, are an important class of nanostructures attracting tremendous interests in the past two decades. In this special issue, seven review articles and research reports are collected, to summarize and present the latest progress in the exploration of ...
Zhuang Liu, Xing-Jie Liang
openaire   +5 more sources

The Theranostic Genome [PDF]

Nature Communications
Theranostic drugs represent an emerging path to deliver on the promise of precision medicine. However, bottlenecks remain in characterizing theranostic targets, identifying theranostic lead compounds, and tailoring theranostic drugs. To overcome these bottlenecks, we present the Theranostic Genome, the part of the human genome whose expression can be ...
Xiaoying Xu, Pablo Jané, Vincent Taelman, Eduardo Jané, Rebecca A. Dumont, Yonathan Garama, Francisco Kim, María del Val Gómez, Karim Gariani, Martin A. Walter   +9 more
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Dendrimers for theranostic applications

Biomolecular Concepts, 2015
AbstractRecently, there have been tremendous advances in the development of various nanotechnology-based platforms for diagnosis and therapy. These nanoplatforms, which include liposomes, micelles, polymers, and dendrimers, comprise highly integrated nanoparticles that provide multiple functions, such as targeting, imaging, and therapy.
Chie Kojima, Ugir Hossain Sk
openaire   +6 more sources

Author Correction: Reprogramming the tumor immune microenvironment using engineered dual-drug loaded Salmonella [PDF]

Nature Communications
Dinh-Huy Nguyen, Sung-Hwan You, Hien Thi-Thu Ngo, Khuynh Van Nguyen, Khang Vuong Tran, Tan-Huy Chu, So-young Kim, Sang-Jun Ha, Yeongjin Hong, Jung-Joon Min   +9 more
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Generation of in situ CRISPR-mediated primary and metastatic cancer from monkey liver

Signal Transduction and Targeted Therapy, 2021
Non-human primates (NHPs) represent the most valuable animals for drug discovery. However, the current main challenge remains that the NHP has not yet been used to develop an efficient translational medicine platform simulating human diseases, such as ...
Liping Zhong, Yong Huang, Jian He, Nuo Yang, Banghao Xu, Yun Ma, Junjie Liu, Chao Tang, Chengpiao Luo, Pan Wu, Zongqiang Lai, Yu Huo, Tao Lu, Dongni Huang, Wenlin Gong, Lu Gan, Yiqun Luo, Zhikun Zhang, Xiyu Liu, Yongxiang Zhao   +19 more
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Current Strategies for Tumor Photodynamic Therapy Combined With Immunotherapy

Frontiers in Oncology, 2021
Photodynamic therapy (PDT) is a low invasive antitumor therapy with fewer side effects. On the other hand, immunotherapy also has significant clinical applications in the treatment of cancer.
Jianfeng Hua, Pan Wu, Lu Gan, Zhikun Zhang, Jian He, Liping Zhong, Yongxiang Zhao, Yong Huang, Yong Huang   +8 more
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Identification of co-expression hub genes for ferroptosis in kidney renal clear cell carcinoma based on weighted gene co-expression network analysis and The Cancer Genome Atlas clinical data

Scientific Reports, 2022
Renal clear cell carcinoma (KIRC) is one of the most common tumors worldwide and has a high mortality rate. Ferroptosis is a major mechanism of tumor occurrence and development, as well as important for prognosis and treatment of KIRC. Here, we conducted
Shengxian Li, Ximei Xu, Ruirui Zhang, Yong Huang   +3 more
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Tuning ultrasmall theranostic nanoparticles for MRI contrast and radiation dose amplification [PDF]

Theranostics, 2023, 13, pp.4711 - 4729, 2023
Background: The introduction of magnetic resonance (MR)-guided radiation treatment planning has opened a new space for theranostic nanoparticles to reduce acute toxicity while improving local control. In this work, second-generation AGuIX nanoparticles (AGuIX-Bi) are synthesized and validated.
arxiv   +1 more source

Proposal of a population wide genome-based testing for Covid-19

Scientific Reports, 2022
Our lives (and deaths) have by now been dominated for two years by COVID-19, a pandemic that has caused hundreds of millions of disease cases, millions of deaths, trillions in economic costs, and major restrictions on our freedom. Here we suggest a novel
Hans Lehrach, Jon Curtis, Bodo Lange, Lesley A. Ogilvie, Richard Gauss, Christoph Steininger, Erhard Scholz, Matthias Kreck   +7 more
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