Results 11 to 20 of about 383,704 (324)

Human Leukemia T-Cell Lines as Alternatives to Animal Use for Detecting Biologically Active Staphylococcal Enterotoxin Type B

open access: yesToxins, 2021
Staphylococcal enterotoxin type B (SEB) is associated with food poisoning. Current methods for the detection of biologically active SEB rely upon its ability to cause emesis when administered to live kittens or monkeys.
Reuven Rasooly   +3 more
doaj   +1 more source

RTX-Toxins [PDF]

open access: yesToxins, 2020
RTX-Toxins (Repeats in ToXin) are members of a rapidly expanding family of proteins [...]
openaire   +4 more sources

Cervical dystonia: non-motor aspects

open access: yesНеврология, нейропсихиатрия, психосоматика, 2020
Cervical dystonia (CD) is manifested by violent, often painful movements of the neck muscles with the abnormal head and/or neck postures being formed. Disease progression leads to disability of patients.
O. A. Druzhinina   +3 more
doaj   +1 more source

Liquid chromatography-tandem mass spectrometry analysis of a ratio-optimized drug pair of Sophora flavescens Aiton and Coptis chinensis Franch and study on the mechanism of anti-colorectal cancer effect of two alkaloids thereof

open access: yesFrontiers in Oncology, 2023
The drug pair consisting of Sophora flavescens Aiton (Sophorae flavescentis radix, Kushen) and Coptis chinensis Franch. (Coptidis rhizoma, Huanglian), as described in Prescriptions for Universal Relief (Pujifang), is widely used to treat laxation ...
Zihan Chen   +14 more
doaj   +1 more source

Coexistence of Competing Microbial Strains under Twofold Environmental Variability and Demographic Fluctuations [PDF]

open access: yesNew J. Phys 25, 123010 (2023), 2023
Microbial populations generally evolve in volatile environments, under conditions fluctuating between harsh and mild, e.g. as the result of sudden changes in toxin concentration or nutrient abundance. Environmental variability thus shapes the long-time population dynamics, notably by influencing the ability of different strains of microorganisms to ...
arxiv   +1 more source

Octyl Gallate Use to Protect Seeds from Foodborne Fungal Pathogens

open access: yesBiology and Life Sciences Forum, 2022
There is limited efficacy with conventional seed sanitation methods, directly affecting food safety. Insufficient elimination of mycotoxin-producing fungi contaminating seed surfaces can result in high mycotoxin contamination.
Jong H. Kim, Kathleen L. Chan
doaj   +1 more source

Toxin-mediated competition in weakly motile bacteria [PDF]

open access: yes2019, J. Theor. Biol. 480 , 205-217, 2019
Many bacterial species produce toxins that inhibit their competitors. We model this phenomenon by extending classic two-species Lotka-Volterra competition in one spatial dimension to incorporate toxin production by one species. Considering solutions comprising two adjacent single-species colonies, we show how the toxin inhibits the susceptible species ...
arxiv   +1 more source

Using Multiscale Molecular Dynamics Simulations to Obtain Insights into Pore Forming Toxin Mechanisms [PDF]

open access: yesMethods in Enzymology (Chapter Sixteen), 2021, 2020
Pore forming toxins (PFTs) are virulent proteins released by several species, including many strains of bacteria, to attack and kill host cells. In this article, we focus on the utility of molecular dynamics (MD) simulations and the molecular insights gleaned from these techniques on the pore forming pathways of PFTs.
arxiv   +1 more source

Botulinum toxin

open access: yesIndian Journal of Dermatology, 2010
Botulinum toxin, one of the most poisonous biological substances known, is a neurotoxin produced by the bacterium Clostridium botulinum. C. botulinum elaborates eight antigenically distinguishable exotoxins (A, B, C(1), C(2), D, E, F and G). All serotypes interfere with neural transmission by blocking the release of acetylcholine, the principal ...
Nigam P, Nigam Anjana
openaire   +3 more sources

Cinnamic Acid Analogs as Intervention Catalysts for Overcoming Antifungal Tolerance

open access: yesMolecules, 2017
Disruption of fungal cell wall should be an effective intervention strategy. However, the cell wall-disrupting echinocandin drugs, such as caspofungin (CAS), cannot exterminate filamentous fungal pathogens during treatment.
Jong H. Kim   +2 more
doaj   +1 more source

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