Results 21 to 30 of about 4,074,715 (354)
Condensin-mediated chromosome organization and gene regulation
Frontiers in Genetics, 2015 In many organisms sexual fate is determined by a chromosome-based method which entails a difference in sex chromosome-linked gene dosage. Consequently, a gene regulatory mechanism called dosage compensation equalizes X-linked gene expression between the ...
Alyssa Christine Lau +1 more
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SnapShot: Chromosome organization.
Molecular Cell, 2022 Chromosomes in higher eukaryotes are folded at different length scales into loop extrusion domains, spatial compartments, and chromosome territories and exhibit interactions with nuclear structures such as the lamina. Microscopic methods can probe this structure by measuring positions of chromosomes in the nuclear space in individual cells, while ...
R. McCord +4 more
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Organization of the bacterial chromosome [PDF]
Microbiological Reviews, 1990 Recent progress in studies on the bacterial chromosome is summarized. Although the greatest amount of information comes from studies on Escherichia coli, reports on studies of many other bacteria are also included. A compilation of the sizes of chromosomal DNAs as determined by pulsed-field electrophoresis is given, as well as a discussion of factors ...
S. Krawiec, Andrew M. Riley
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THE PARTICULATE ORGANIZATION OF THE CHROMOSOME [PDF]
Proceedings of the National Academy of Sciences, 1954 Daniel Mazia
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Two major mechanisms of chromosome organization. [PDF]
Curr Opin Cell Biol, 2019 Mirny LA, Imakaev M, Abdennur N.
europepmc +2 more sources
Chromatin Domains: The Unit of Chromosome Organization. [PDF]
Mol Cell, 2016 Dixon JR, Gorkin DU, Ren B.
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Nuclear Organization and Chromosome Segregation [PDF]
The Plant Cell, 1999 The genetic information underlying plant form and function is contained within the cell nucleus in the form of complex, dynamic DNA–protein structures—the chromosomes. The faithful transmission of these structures during mitosis and meiosis requires extensive chromosome reorganization and ...
A. E. Franklin, W. Zacheus Cande
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Extrusion fountains are hallmarks of chromosome organization emerging upon zygotic genome activation
bioRxiv, 2023 The first activation of gene expression during development (zygotic genome activation, ZGA) is accompanied by massive changes in chromosome organization. The connection between these two processes remains unknown.
Aleksandra Galitsyna +9 more
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eLife, 2022 The MCM2–7 hetero-hexamer is the replicative DNA helicase that plays a central role in eukaryotic DNA replication. In proliferating cells, the expression level of the MCM2–7 hexamer is kept high, which safeguards the integrity of the genome. However, how
Yuichiro Saito +3 more
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Crumpled polymer with loops recapitulates key features of chromosome organization
bioRxiv, 2022 Chromosomes are exceedingly long topologically-constrained polymers compacted in a cell nucleus. We recently suggested that chromosomes are organized into loops by an active process of loop extrusion.
K. Polovnikov +4 more
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