Indian Dermatology Online Journal, 2014 Crohn′s disease, first described in 1922, is characterized by segmental granulomatous inflammation of the intestinal tract and frequently involves the cutaneous tissues as well.
Padmavathy Lanka +4 more
doaj +1 more source
Research progress on risk factors for anastomotic recurrence after Crohn disease [PDF]
Yixue xinzhi zazhi, 2023 Intestinal resection and reconstruction are crucial steps in surgical treatment for Crohn disease. However, anastomotic recurrence is a common complication following reconstruction surgery.
Bao-Jia YAO +3 more
doaj +1 more source
Higher risk of tuberculosis reactivation when anti-TNF is combined with immunosuppressive agents. A systematic review of randomized controlled trials [PDF]
, 2014 Objective. Treatment with tumour necrosis factor antagonists (anti-TNF) has been recognized as a risk factor for tuberculosis (TB) reactivation. Our aim was to evaluate risk of TB reactivation in rheumatologic and non-rheumatologic diseases treated with ...
Armuzzi, Alessandro +9 more
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Strategies and methods of medical therapy for refractory Crohn's disease [PDF]
Yixue xinzhi zazhi, 2022 Crohn's disease (CD) is an inflammatory bowel disease that can affect the entire digestive tract. Although new drugs have been introduced in recent years, there are still some patients who are unresponsive to various treatments.
Qiao ZHONG, A-Kang SHAO, Min CHEN
doaj +1 more source
Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: Pathogenic bacteria and altered bacterial sensing or changes in mucosal integrity take "toll"? [PDF]
, 2006 The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various environmental and host (e.g. genetic-, epithelial-, immune and non-immune) factors are involved.
Fischer, Simon +4 more
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Chronic linear ulcerations of the inguino-crural and buttocks folds
Indian Journal of Dermatology, 2011 Vulvo-perineal Crohn′s disease is a rare condition either when it is isolated or associated with digestive manifestations. In the former condition named metastatic Crohn′s disease, it may constitute a diagnostic challenge and may be confused especially ...
Aida Khaled +5 more
doaj +1 more source
Crohn's disease activity index and Vienna classification - Is it worthwhile to calculate before surgery? [PDF]
, 2006 Background: Crohn's disease (CD) patients with increased disease activity may reveal an increased risk for perioperative complications. The `Crohn's disease activity index' (CDAI) and the `Vienna classification' (VC) were developed for standardized ...
A. Beham +29 more
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DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis [PDF]
, 2014 Inflammatory bowel diseases (IBD) are emerging globally, indicating that environmental factors may be important in their pathogenesis. Colonic mucosal epigenetic changes, such as DNA methylation, can occur in response to the environment and have been ...
Bronsky, Jiri +10 more
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Journal of British Surgery, 1958 39 of 40 patients treated by the author up to 18 years with corticosteroids, antibiotics and psychotherapy replied to a postal questionnaire in 1969. For details, see table I. Previous reports of the relevance of emotional stress and personality to the etiology of Crohn’s disease are summarized together with types of provocative stress and personality ...
openaire +7 more sources
Autophagy and Crohn's Disease [PDF]
Journal of Innate Immunity, 2013 Advances in genetics have shed light on the molecular basis of Crohn's disease (CD) predisposition and pathogenesis, via linkage disequilibrium analysis to genome-wide association studies. The discovery of genetic variants of <i>NOD2</i>, an intracellular pathogen molecular sensor, as risk factors for CD has paved the way for further ...
Hang Thi Thu Nguyen, - +3 more
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