Results 21 to 30 of about 2,115,482 (343)

Pathophysiology of Type 2 Diabetes Mellitus

International Journal of Molecular Sciences, 2020
Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to ...
U. Galicia-Garcia, A. Benito-Vicente, S. Jebari, A. Larrea-Sebal, H. Siddiqi, K. Uribe, H. Ostolaza, César Martín   +7 more
semanticscholar   +1 more source

Identification of Micronuclei in the Lymphocytes of the Type 2 Diabetes Mellitus According to the Period of Diagnosis as a Biomarker

Polytechnic Journal, 2023
Micronuclei in lymphocytes can indicate DNA damage or chromosomal instability. This study aimed to compare the Micronuclei to the different period diagnoses of type 2 diabetes mellitus. Four groups were created out of 140 people: type 2 diabetes mellitus
Harem Othman Smail
doaj   +1 more source

Mapping the methylation status of the miR-145 promoter in saphenous vein smooth muscle cells from individuals with type 2 diabetes [PDF]

, 2016
Type 2 diabetes mellitus prevalence is growing globally, and the leading cause of mortality in these patients is cardiovascular disease. Epigenetic mechanisms such as microRNAs (miRs) and DNA methylation may contribute to complications of type 2 diabetes
Huntriss, J, Keeble, CM, O'Regan, DJ, Porter, KE, Riches, K, Turner, NA, Wood, IC   +6 more
core   +2 more sources

Facilitators and barriers of adaptation to diabetes: experiences of Iranian patients [PDF]

, 2014
Background: Diabetes mellitus is one of the most challenging and burdensome chronic diseases of the 21st century and More than 1% of the Iranian urban population older than 20 years develops Type 2 diabetes each year.
Arshadi Bostanabad, M., Jouybari, L., Karimi Moonaghi, H., McDonald, H., Namdar Areshtanab, H.   +4 more
core   +2 more sources

Bromocriptine in type 2 diabetes mellitus

Indian Journal of Endocrinology and Metabolism, 2011
Bromocriptine mesylate quick-release was approved by the Food and Drug Administration (FDA) in May 2009, for the treatment of type 2 diabetes. Bromocriptine is thought to act on the circadian neuronal activities in the hypothalamus, to reset an ...
C Shivaprasad, Sanjay Kalra
doaj   +1 more source

Recent Developments in Biomarkers for Diagnosis and Screening of Type 2 Diabetes Mellitus

Current Diabetes Reports, 2022
Diabetes mellitus is a complex, chronic illness characterized by elevated blood glucose levels that occurs when there is cellular resistance to insulin action, pancreatic β-cells do not produce sufficient insulin, or both. Diabetes prevalence has greatly
Margarita Ortíz-Martínez, M. González‐González, Alexandro J. Martagon, Victoria Hlavinka, Richard C. Willson, M. Rito‐Palomares   +5 more
semanticscholar   +1 more source

Metformin treatment for diabetes mellitus correlates with progression and survival in colorectal carcinoma [PDF]

, 2020
BACKGROUND: Diabetes mellitus is unfavorably associated with cancer risk. The purpose of this multi-disciplinary project was to evaluate a possible association of diabetes mellitus and other comorbidities and their treatment with progression of ...
Brown, Robert E., Cempírková, Dana, Dundr, Pavel, Gregorová, Jana, Grimmichová, Tereza, Heneberg, Petr, Janurová, Kateřina, Litschmannová, Martina, Pešta, Michal, Powell, Marta K., Třebický, Ferdinand   +10 more
core   +1 more source

Cardiovascular disease in type 2 diabetes mellitus: progress toward personalized management

Cardiovascular Diabetology, 2022
Cardiovascular diseases (CVDs) are the main cause of death among patients with type 2 diabetes mellitus (T2DM), particularly in low- and middle-income countries. To effectively prevent the development of CVDs in T2DM, considerable effort has been made to
Cheng-Xu Ma, Xiao-Ni Ma, C. Guan, Ying-dong Li, D. Mauricio, S. Fu   +5 more
semanticscholar   +1 more source

Forecasting the type 2 diabetes mellitus epidemic and the role of key risk factors in Oman up to 2050: Mathematical modeling analyses

Journal of Diabetes Investigation, 2021
Aims/Introduction To investigate and forecast type 2 diabetes mellitus epidemic, its related risk factors and cost in Oman by 2050. Materials and Methods An age‐structured mathematical model was used to characterize type 2 diabetes mellitus epidemiology ...
Susanne F Awad, Adhra Al‐Mawali, Jawad A Al‐Lawati, Magdi Morsi, Julia A Critchley, Laith J Abu‐Raddad   +5 more
doaj   +1 more source

Gestational diabetes mellitus and progression to type 2 diabetes [PDF]

Romanian Journal of Medical Practice, 2021
Diabetes mellitus is a metabolic disease with life-threatening morbidity and with epidemic spread. This metabolic disorder affects an increasing number of pregnant women.
Delia Ioana CUDALBA, Nicolae GICA, Radu BOTEZATU, Corina GICA, Anca Marina CIOBANU, Brindușa Ana CIMPOCA, Alina VEDUTA, Gheorghe PELTECU, Anca Maria PANAITESCU   +8 more
doaj   +1 more source