Results 21 to 30 of about 167,091 (283)

Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]

open access: yes, 2018
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J.   +2 more
core   +1 more source

CXCL16 and oxLDL are induced in the onset of diabetic nephropathy [PDF]

open access: yes, 2009
Diabetic nephropathy (DN) is a major cause of end-stage renal failure worldwide. Oxidative stress has been reported to be a major culprit of the disease and increased oxidized low density lipoprotein (oxLDL) immune complexes were found in patients with ...
Abdel-Aziz, Abdel-Aziz H.   +11 more
core   +1 more source

Diabetic Nephropathy without Diabetes [PDF]

open access: yesJournal of Clinical Medicine, 2015
Diabetic nephropathy without diabetes (DNND), previously known as idiopathic nodular glomerulosclerosis, is an uncommon entity and thus rarely suspected; diagnosis is histological once diabetes is discarded. In this study we describe two new cases of DNND and review the literature. We analyzed all the individualized data of previous publications except
López-Revuelta, Katia   +5 more
openaire   +3 more sources

High glucose up-regulates ENaC and SGK1 expression in HCD-cells [PDF]

open access: yes, 2006
Background/Aim: Diabetic nephropathy is associated with progressive renal damage, leading to impaired function and end-stage renal failure. Secondary hypertension stems from a deranged ability of cells within the kidney to resolve and appropriately ...
Bell LM   +30 more
core   +1 more source

Pathophysiology of mesangial expansion in diabetic nephropathy: mesangial structure, glomerular biomechanics, and biochemical signaling and regulation

open access: yesJournal of Biological Engineering, 2022
Diabetic nephropathy, a kidney complication arising from diabetes, is the leading cause of death in diabetic patients. Unabated, the growing epidemic of diabetes is increasing instances of diabetic nephropathy.
Haryana Y. Thomas   +1 more
doaj   +1 more source

Urinary excretion of RAS, BMP, and WNT pathway components in diabetic kidney disease. [PDF]

open access: yes, 2014
The renin-angiotensin system (RAS), bone morphogenetic protein (BMP), and WNT pathways are involved in pathogenesis of diabetic kidney disease (DKD).
Afkarian, Maryam   +5 more
core   +1 more source

Managing diabetic nephropathy [PDF]

open access: yesClinical Medicine, 2010
The earliest sign of DN is the development of microalbuminuria which is associated with a significant risk of both progressive renal failure and premature death from cardiovascular disease. Optimal glycaemic and BP control, including the use of RAAS blocking drugs, can prevent, slow and even reverse the processes causing DN.
Shields, Joanne, Maxwell, Alexander P
openaire   +2 more sources

Awareness of diabetic nephropathy in patients with type 2 diabetes mellitus: the Indian scenario [PDF]

open access: yesJournal of Nephropharmacology, 2018
Introduction: Diabetic nephropathy is an important complication of diabetes mellitus leading to significant morbidity and mortality. Objectives: To study the awareness of diabetic nephropathy in patients with type 2 diabetes mellitus (T2DM) and the ...
Chirag Bansal   +2 more
doaj  

PENURUNAN BILIRUBIN MENINGKATKAN OKSIDASI LIPOPROTEIN A PADA NEFROPATI DIABETIK

open access: yesJKS (Jurnal Kedokteran Syiah Kuala), 2017
. Diabetic nephropathy is the most common complication of microvascular disease due to diabetes and the third leading cause of renal failure to the end stage.
Meutia Atika Faradilla   +2 more
doaj   +1 more source

Diabetic kidney disease. new clinical and therapeutic issues. Joint position statement of the Italian Diabetes Society and the Italian Society of Nephrology on "the natural history of diabetic kidney disease and treatment of hyperglycemia in patients with type 2 diabetes and impaired renal function" [PDF]

open access: yes, 2019
Recent epidemiological studies have disclosed heterogeneity in diabetic kidney disease (DKD). In addition to the classical albuminuric phenotype, two new phenotypes have emerged, i.e., “nonalbuminuric renal impairment” and “progressive renal decline ...
Barutta, Federica   +7 more
core   +1 more source

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