Results 21 to 30 of about 280,511 (396)

Heavy and light chains of a homogeneous immunoglobulin‐G [PDF]

FEBS Letters, 1969
Zuhayr L. Awdeh, Alan R. Williamson, Brigitte A. Askonas   +2 more
openalex   +5 more sources

Systematic characterization of immunoglobulin loci and deep sequencing of the expressed repertoire in the Atlantic cod (Gadus morhua) [PDF]

BMC Genomics
Background The Atlantic cod is a prolific species in the Atlantic, despite its inconsistent specific antibody response. It presents a peculiar case within vertebrate immunology due to its distinct immune system, characterized by the absence of MHCII ...
Ádám Györkei, Finn-Eirik Johansen, Shuo-Wang Qiao   +2 more
doaj   +2 more sources

Some structural features of the peptide profile of myelin basic protein-hydrolyzing antibodies in schizophrenic patients [PDF]

PeerJ, 2023
The antibodies of schizophrenic patients that hydrolyze myelin basic protein (MBP) have been actively studied recently, but the mechanism of the catalytic properties of immunoglobulin molecules remains unknown.
Maria Zavialova, Daria Kamaeva, Laura Kazieva, Vladlen S. Skvortsov, Liudmila Smirnova   +4 more
doaj   +2 more sources

Triple immunoglobulin gene knockout transchromosomic cattle: bovine lambda cluster deletion and its effect on fully human polyclonal antibody production. [PDF]

PLoS ONE, 2014
Towards the goal of producing fully human polyclonal antibodies (hpAbs or hIgGs) in transchromosomic (Tc) cattle, we previously reported that Tc cattle carrying a human artificial chromosome (HAC) comprising the entire unrearranged human immunoglobulin ...
Hiroaki Matsushita, Akiko Sano, Hua Wu, Jin-An Jiao, Poothappillai Kasinathan, Eddie J Sullivan, Zhongde Wang, Yoshimi Kuroiwa   +7 more
doaj   +1 more source

Antibody Light Chains: Key to Increased Monoclonal Antibody Yields in Expi293 Cells?

Antibodies, 2022
When constructing isogenic recombinant IgM–IgG pairs, we discovered that μ heavy chains strongly prefer partnering with λ light chains for optimal IgM expression in transiently cotransfected Expi293 cells.
Siqi Gong, Seijal Gautam, Joshua D. Coneglio, Hanna B. Scinto, Ruth M. Ruprecht   +4 more
doaj   +1 more source

Immunoglobulin heavy chain gene rearrangement in heavy chain deposition disease suggests it is a plasma cell disease: a case report

Journal of International Medical Research, 2022
Heavy chain deposition disease (HCDD) is characterized by the deposition of truncated monoclonal immunoglobulin heavy chains along glomerular basement membranes.
Qingqing Rao, Ricong Xu, Qijun Wan
doaj   +1 more source

Human Gm, Km, and Am Allotypes: WHO/IMGT Nomenclature and IMGT Unique Numbering for Immunoinformatics and Therapeutical Antibodies

BioMedInformatics, 2023
Human immunoglobulin allotypes are allelic antigenic determinants (or “markers”) determined serologically, classically by hemagglutination inhibition, on the human immunoglobulin (IG) or antibody heavy and light chains. The allotypes have been identified
Marie-Paule Lefranc, Gérard Lefranc
doaj   +1 more source

The Leukocyte Immunoglobulin-Like Receptor Family Member LILRB5 Binds to HLA-Class I Heavy Chains. [PDF]

PLoS ONE, 2015
The leukocyte immunoglobulin-like receptor (LILR) family includes inhibitory and stimulatory members which bind to classical and non-classical HLA-class I.
Zhiyong Zhang, Hiroko Hatano, Jacqueline Shaw, Marloes Olde Nordkamp, Guosheng Jiang, Demin Li, Simon Kollnberger   +6 more
doaj   +1 more source

Gamma heavy chain disease associated with T-cell large granular lymphocyte lymphoproliferative disorder: case report and literature review.

Mediterranean Journal of Hematology and Infectious Diseases, 2023
Heavy chain diseases are rare B-cell neoplasms consisting of the production of a monoclonal immunoglobulin composed of the only heavy chain without corresponding light chains.
Maria Laura Bisegna, Maria Assunta Limongiello, Stefano Fiori, Maria Stefania De Propris, Irene Della Starza, Stefania Trasarti   +5 more
doaj   +1 more source

A Hands-on Activity for V(D)J Recombination in an Undergraduate Immunology Class

Journal of Microbiology & Biology Education, 2023
This learning activity teaches the difficult concept of V(D)J recombination as it occurs in B cells. Following the traditional lecture, this hands-on activity uses pipe cleaners of various colors representing variable, joining, and diversity gene ...
Kelly N. Hallstrom, Gwendowlyn S. Knapp
doaj   +1 more source