Results 21 to 30 of about 203,270 (263)
Predicting Dosage of Immunosuppressant Drugs After Kidney Transplantation Using Machine Learning [PDF]
While kidney transplants are seen as the best treatment option for patients with end-stage renal disease and kidney failure, the organ's health depends on the dosage of immunosuppressant drugs post-transplantation. Due to the dosage variance based on each patient's unique physiology, nephrologists face numerous difficulties when determining the precise
arxiv
Nonimmunologic targets of immunosuppressive agents in podocytes
Proteinuria is a characteristic finding in glomerular diseases and is closely associated with renal outcomes. In addition, therapeutic interventions that reduce proteinuria improve renal prognosis.
Tae-Hyun Yoo, Alessia Fornoni
doaj +1 more source
Immune Response to Vaccination in Patients with Psoriasis Treated with Systemic Therapies
Psoriasis is a chronic inflammatory skin disease usually treated with immunomodulatory/immunosuppressive agents. The use of these agents has been associated with an increased susceptibility to infections.
Andrea Chiricozzi+3 more
doaj +1 more source
Optimal Kidney Exchange with Immunosuppressants [PDF]
Algorithms for exchange of kidneys is one of the key successful applications in market design, artificial intelligence, and operations research. Potent immunosuppressant drugs suppress the body's ability to reject a transplanted organ up to the point that a transplant across blood- or tissue-type incompatibility becomes possible.
arxiv
Quantitative Methods for Optimizing Patient Outcomes in Liver Transplantation [PDF]
Liver transplantation continues to be the gold standard for treating patients with end-stage liver diseases. However, despite the huge success of liver transplantation in improving patient outcomes, long term graft survival continues to be a major problem.
arxiv
Triiodothyronine suppresses humoral immunity but not T-cell-mediated immune response in incubating female eiders (Somateria mollissima) [PDF]
Immunity is believed to share limited resources with other physiological functions and this may partly account for the fitness costs of reproduction. Previous studies have shown that the acquired immunity of female common eiders (Somateria mollissima) is suppressed during the incubation fast.
arxiv +1 more source
New immunosuppressive agents in transplantation
Immunosuppressive agents have enabled the development of allogenic transplantation during the last 40 years, allowing considerable improvement in graft survival. However, several issues remain such as the nephrotoxicity of calcineurin inhibitors, the cornerstone of immunosuppressive regimens and/or the higher risk of opportunistic infections and ...
Kervella, Delphine, Blancho, Gilles
openaire +4 more sources
Phaeohyphomycosis in renal transplantation: report of two cases [PDF]
Phaeohyphomycosis is an infection caused by a filamentous fungus that contains pigment melanin in its cell wall. We report two cases caused by Exophiala sp.
Walmar Roncalli Pereira de Oliveira+5 more
doaj +1 more source
Background Baricitinib is the first JAK inhibitor registered for the treatment of moderate‐to‐severe atopic dermatitis (AD). Efficacy and safety were shown in clinical trials, but daily practice data is sparse.
Linde deWijs+4 more
doaj +1 more source
Cooperative coinfection dynamics on clustered networks [PDF]
Coinfection is the process by which a host that is infected with a pathogen becomes infected by a second pathogen at a later point in time. An immunosuppressant host response to a primary disease can facilitate spreading of a subsequent emergent pathogen among the population.
arxiv +1 more source