Hepatitis C virus relies on lipoproteins for its life cycle [PDF]
, 2016 Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino +5 more
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Characterization of hepatic low density lipoprotein binding and cholesterol metabolism in normal and homozygous familial hypercholesterolemic subjects [PDF]
, 1984 Patients with familial hypercholesterolemia have elevated levels of plasma low density lipoproteins (LDL), increased hepatic synthesis of apolipoprotein B-containing lipoproteins, defective binding of low density lipoproteins to fibroblasts, and ...
Brewer, HB +4 more
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Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia [PDF]
, 1984 A six-year-old girl with severe hypercholesterolemia and atherosclerosis had two defective genes at the low-density-lipoprotein (LDL) receptor locus, as determined by biochemical studies of cultured fibroblasts.
Cummings +9 more
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Pathophysiology of elevated ascites fluid cholesterol in malignant ascites [PDF]
, 1992 The existence of marked elevations of ascitic fluid cholesterol has been observed in patients with peritoneal carcinomatosis compared to patients with cirrhosis and has been found useful in differential diagnosis.
Alexander L. Gerbes +27 more
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Quantification of LDL-Cholesterol Corrected for Molar Concentration of Lipoprotein(a)
Cardiovascular Drugs and Therapy, 2022 Abstract Purpose Cholesterol in lipoprotein(a) [Lp(a)-C] is commonly estimated as 30% of the measured Lp(a) mass. However, difficulties in the accurate measurement of Lp(a) mass, along with the inaccuracy of the 30% assumption, produce erroneous values when LDL-C is corrected for Lp(a) [LDL-CLp(a)corr].
Robert S. Rosenson +5 more
openaire +2 more sources
Hepatitis C virus production requires apolipoprotein A-I and affects its association with nascent low-density lipoproteins [PDF]
, 2011 Background/aims The life cycle of hepatitis C virus (HCV) is intimately linked to the lipid metabolism of the host. In particular, HCV exploits the metabolic machinery of the lipoproteins in several steps of its life cycle such as circulation in the ...
Amicone, Laura +11 more
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Blood rheology, cardiovascular risk factors, and cardiovascular disease: The West of Scotland Coronary Prevention Study [PDF]
, 2000 The West of Scotland Coronary Prevention Study (WOSCOPS) showed that pravastatin reduced the risk of coronary heart disease (CHD) events in 6,595 middle-aged hypercholesterolaemic men aged 45-64 years without prior myocardial infarction followed for an ...
Ann Rumley +8 more
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Effects of pH and Low Density Lipoprotein (LDL) on PCSK9-dependent LDL Receptor Regulation [PDF]
Journal of Biological Chemistry, 2007 Mutations within PCSK9 (proprotein convertase subtilisin/kexin type 9) are associated with dominant forms of familial hyper- and hypocholesterolemia. Although PCSK9 controls low density lipoprotein (LDL) receptor (LDLR) levels post-transcriptionally, several questions concerning its mode of action remain unanswered.
Fisher, Timothy S. +15 more
openaire +4 more sources
Antihyperlipidemic Activities of Common Garden Peony ( Paeonia lactifl ora Pall.) [PDF]
Mongolian Journal of Biological Sciences, 2013 We studied different extracts of aboveground and underground parts of Paeonia lactifl ora Pall.in experiment. For doing so this research needs to start up with total cholesterol.
Tserenlkham Tserendejid +3 more
doaj +1 more source
Plasma lipoprotein subfraction concentrations are associated with lipid metabolism and age-related macular degeneration [PDF]
, 2017 10.1194/jlr.M073684Journal of Lipid Research5891785 ...
Apte, Rajendra S. +10 more
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