Human Vaccines & Immunotherapeutics, 2023 Optimum formulation of Biological-E’s protein subunit CORBEVAX™ vaccine was selected in phase-1 and -2 studies and found to be safe and immunogenic in healthy adult population.
Subhash Thuluva +21 more
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Carbohydrate Ligands for COVID-19 Spike Proteins
Viruses, 2022 An outbreak of SARS-CoV-2 coronavirus (COVID-19) first detected in Wuhan, China, has created a public health emergency all over the world. The pandemic has caused more than 340 million confirmed cases and 5.57 million deaths as of 23 January 2022 ...
Yung-Kuo Lee +7 more
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The effect of signal pathways on the neural KATP subunits SUR1/Kir6.2 expression induced by Aβ1-42
Chinese Journal of Contemporary Neurology and Neurosurgery, 2021 Objective To investigate the potential signal transduction mechanism of β⁃amyloid protein1-42 (Aβ1-42) induced up⁃regulation of ATP sensitive potassium channel KATP subunit SUR1/Kir6.2 proteins expression.
LI Yan⁃ju +4 more
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Self-subunit swapping occurs in another gene type of cobalt nitrile hydratase. [PDF]
PLoS ONE, 2012 Self-subunit swapping is one of the post-translational maturation of the cobalt-containing nitrile hydratase (Co-NHase) family of enzymes. All of these NHases possess a gene organization of , which allows the activator protein to easily form a ...
Yi Liu +5 more
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Influence of Conformation of M. tuberculosis RNase P Protein Subunit on Its Function. [PDF]
PLoS ONE, 2016 RNase P is an essential enzyme that processes 5' end leader sequence of pre-tRNA to generate mature tRNA. The bacterial RNase Ps contain a RNA subunit and one protein subunit, where the RNA subunit contains the catalytic activity.
Alla Singh +3 more
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Direct Interaction of Avian Cryptochrome 4 with a Cone Specific G-Protein
Cells, 2022 Background: Night-migratory birds sense the Earth’s magnetic field by an unknown molecular mechanism. Theoretical and experimental evidence support the hypothesis that the light-induced formation of a radical-pair in European robin cryptochrome 4a ...
Katharina Görtemaker +11 more
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Allotopic Expression of a Gene Encoding FLAG Tagged-subunit 8 of Yeast Mitochondrial ATP Synthase
Hayati Journal of Biosciences, 2006 Subunit 8 of yeast mitochondrial ATP synthase is a polypeptide of 48 amino acids encoded by the mitochondrial ATP8 gene. A nuclear version of subunit 8 gene has been designed to encode FLAG tagged-subunit 8 fused with a mitochondrial signal peptide.
I MADE ARTIKA
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Breaking tolerance in transgenic mice expressing the human TSH receptor A-subunit: thyroiditis, epitope spreading and adjuvant as a 'double edged sword'. [PDF]
PLoS ONE, 2012 Transgenic mice with the human thyrotropin-receptor (TSHR) A-subunit targeted to the thyroid are tolerant of the transgene. In transgenics that express low A-subunit levels (Lo-expressors), regulatory T cell (Treg) depletion using anti-CD25 before ...
Sandra M McLachlan +4 more
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Interaction between the assembly of the ribosomal subunits: Disruption of 40S ribosomal assembly causes accumulation of extra-ribosomal 60S ribosomal protein uL18/L5. [PDF]
PLoS ONE, 2020 Inhibition of the synthesis of an essential ribosomal protein (r-protein) abrogates the assembly of its cognate subunit, while assembly of the other subunit continues.
Nusrat Rahman +2 more
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How to change the oligomeric state of a circular protein assembly: switch from 11-subunit to 12-subunit TRAP suggests a general mechanism. [PDF]
PLoS ONE, 2011 Many critical cellular functions are performed by multisubunit circular protein oligomers whose internal geometry has evolved to meet functional requirements.
Chao-Sheng Chen +6 more
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