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Marrow stromal stem cells [PDF]

Journal of Clinical Investigation, 2000
Multipotential marrow stromal stem cells were known as early as 1968 (1) through the work of Friedenstein and his coworkers, who established that cells that are adherent, clonogenic, nonphagocytic, and fibroblastic in habit (defined as colony-forming units–fibroblastic; CFU-Fs) can be isolated from the bone marrow stroma of postnatal organisms. CFU-Fs,
BIANCO, Paolo, Pamela Gehron Robey
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Failure of intravenous or intracardiac delivery of mesenchymal stromal cells to improve outcomes after focal traumatic brain injury in the female rat. [PDF]

PLoS ONE, 2015
Mesenchymal stromal cells secrete a variety of anti-inflammatory factors and may provide a regenerative medicine option for the treatment of traumatic brain injury.
L Christine Turtzo, Matthew D Budde, Dana D Dean, Eric M Gold, Bobbi K Lewis, Lindsay Janes, Jacob Lescher, Tiziana Coppola, Angela Yarnell, Neil E Grunberg, Joseph A Frank   +10 more
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Mesenchymal Stromal Cells

Postępy Higieny i Medycyny Doświadczalnej, 2014
Mesenchymal stromal cells (MSCs) have been among the most intensively studied cells in recent years. Lack of specific unique markers for these cells makes it difficult to distinguish MSCs from other types of cells, such as fibroblasts or pericytes. MSCs are a mixture of morphologically different cells with expression of various cellular markers, with ...
Stanisław Szala, Ewa Wiśniewska, Justyna Czapla   +2 more
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Mesenchymal stromal cells [PDF]

Current Opinion in Hematology, 2006
Our understanding of the biology and properties of mesenchymal stem cells or multipotent mesenchymal stromal cells has expanded dramatically over the last 3 years and is likely to have an impact on clinical practice in the near future, making a review of this topic both timely and relevantRecommendations regarding nomenclature and the definition of ...
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A Substrate-Mimicking Basement Membrane Drives the Organization of Human Mesenchymal Stromal Cells and Endothelial Cells Into Perivascular Niche-Like Structures

Frontiers in Cell and Developmental Biology, 2021
Extracellular matrix-derived products (e.g. Matrigel) are widely used for in vitro cell cultures both as two-dimensional (2D) substrates and as three-dimensional (3D) encapsulation gels because of their ability to control cell phenotypes through ...
Valeria Perugini, Matteo Santin
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CD271 antigen defines a subset of multipotent stromal cells with immunosuppressive and lymphohematopoietic engraftment-promoting properties

Haematologica, 2010
Background In vitro proliferative and differentiation potential of mesenchymal stromal cells generated from CD271+ bone marrow mononuclear cells (CD271-mesenchymal stromal cells) has been demonstrated in several earlier and recent reports. In the present
Selim Kuçi, Zyrafete Kuçi, Hermann Kreyenberg, Erika Deak, Kathrin Pütsch, Sabine Huenecke, Chandrasekhar Amara, Stefanie Koller, Eva Rettinger, Manuel Grez, Ulrike Koehl, Hatixhe Latifi-Pupovci, Reinhard Henschler, Torsten Tonn, Dorothee von Laer, Thomas Klingebiel, Peter Bader   +16 more
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Bovine endometrial stromal cells display osteogenic properties

Reproductive Biology and Endocrinology, 2008
The endometrium is central to mammalian fertility. The endometrial stromal cells are very dynamic, growing and differentiating throughout the estrous cycle and pregnancy.
Cavirani Sandro, Capocefalo Antonio, Franceschi Valentina, Donofrio Gaetano, Sheldon Iain   +4 more
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Multipotent mesenchymal stromal cells from amniotic fluid: solid perspectives for clinical application

Haematologica, 2008
Background Mesenchymal stromal cells are multipotent cells considered to be of great promise for use in regenerative medicine. However, the cell dose may be a critical factor in many clinical conditions and the yield resulting from the ex vivo expansion ...
Nadia Sessarego, Alessia Parodi, Marina Podestà, Federica Benvenuto, Massimo Mogni, Valentina Raviolo, Mario Lituania, Annalisa Kunkl, Guido Ferlazzo, Franca Dagna Bricarelli, Antonio Uccelli, Francesco Frassoni   +11 more
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Expression of the melanoma cell adhesion molecule in human mesenchymal stromal cells regulates proliferation, differentiation, and maintenance of hematopoietic stem and progenitor cells

Haematologica, 2013
The melanoma cell adhesion molecule defines mesenchymal stromal cells in the human bone marrow that regenerate bone and establish a hematopoietic microenvironment in vivo.
Sabine Stopp, Martin Bornhäuser, Fernando Ugarte, Manja Wobus, Matthias Kuhn, Sebastian Brenner, Sebastian Thieme   +6 more
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Differential roles of prostaglandin E2 EP4 receptor on stromal cell populations for hematopoietic stem and progenitor cell function

Frontiers in Hematology, 2023
Prostaglandin E2 (PGE2) signaling through its EP4 receptor regulates hematopoietic stem and progenitor cell (HSPC) functions. Here we generated mouse strains with conditional and inducible deletion of EP4 in stromal cell populations, including ...
Liqiong Liu, Hongge Li, Pratibha Singh, Jonathan Hoggatt, Louis M. Pelus, Louis M. Pelus   +5 more
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