Results 21 to 30 of about 229,483 (161)
Tumor Necrosis Factor Alpha-Mediated Asthma? [PDF]
International Archives of Allergy and Immunology, 2012 Thus the pathophysiology of allergic asthma is traditionally explained by mast celland/or Th2 cell-mediated airway inflammation, which is a manifestation of the acquired immune response. On the other hand, recent studies have identified various other important molecules associated with phenotypes of asthma, including tumor necrosis factor (TNF)[2, 3] ,
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Evaluation of Tumor Necrosis Factor Alpha Polymorphism Frequencies in Endometriosis [PDF]
International Journal of Fertility and Sterility, 2015 Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are ...
Roshanak Abutorabi +4 more
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Targeting Tumor Necrosis Factor Alpha for Alzheimer’s Disease [PDF]
Current Alzheimer Research, 2017 Alzheimer’s disease (AD) affects an estimated 44 million individuals worldwide, yet no therapeutic intervention is available to stop the progression of the dementia. Neuropathological hallmarks of AD are extracellular deposits of amyloid beta (Aβ) peptides assembled in plaques, intraneuronal accumulation of hyperphosphorylated tau protein forming ...
Decourt, Boris +2 more
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Revista Brasileira de Hematologia e Hemoterapia, 2014 Background: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha.
Marília Rocha Laurentino +5 more
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The concentration of tumor necrosis factor alpha in periapical lesions [PDF]
Stomatološki glasnik Srbije, 2014 Introduction. The balance between proinflammatory and anti-inflammatory cytokines plays an important role in the pathogenesis of chronic periapical lesions.
Popović Jelena +6 more
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The assessment of TNF-α interaction with oligopeptide Trp-Asn-Trp-Val in vitro [PDF]
Вестник Витебского государственного медицинского университета, 2022 The hyperproduction of TNF-α in the human body is a pathogenetic factor of many diseases development. The widespread clinical use of anticytokine drugs based on antibodies has a number of limitations.
T.V. Ryabtseva +2 more
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Tumor necrosis factor alpha in sleep regulation
Sleep Medicine Reviews, 2018 This review details tumor necrosis factor alpha (TNF) biology and its role in sleep, and describes how TNF medications influence sleep/wake activity. Substantial evidence from healthy young animals indicates acute enhancement or inhibition of endogenous brain TNF respectively promotes and inhibits sleep.
Sigrid C. Veasey +9 more
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Iatreia, 2018 Tumor necrosis factor receptor periodic syndrome (TRAPS) is characterized by episodes of fever of more than 10 days of duration, migratory myalgias, pseudocellulitis, abdominal pain and bipalpebral edema.
Moreno Zuluaga, Catalina +1 more
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Tumor Necrosis Factor Alpha: Implications of Anesthesia on Cancers
Cancers, 2023 Cancer remains a major public health issue and a leading cause of death worldwide. Despite advancements in chemotherapy, radiation therapy, and immunotherapy, surgery is the mainstay of cancer treatment for solid tumors. However, tumor cells are known to disseminate into the vascular and lymphatic systems during surgical manipulation.
Wei-Cheng Tseng +4 more
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Implication of Tumor Necrosis Factor - Alpha in Preeclampsia [PDF]
Applied Medical Informatics, 2008 Introduction: Preeclampsia is an exacerbation of a generalized inflammatory response, physiologically present in the third trimester of pregnancy.Aim: The aim of the study consists in the evaluation of proinflammatory cytokine TNF-α in the context of ...
Dan MIHU +4 more
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