Results 31 to 40 of about 321,644 (366)

Myasthenia Gravis Masquerading as an Idiopathic Unilateral Facial Paralysis (Bell's Palsy)—A Very Rare and Unique Clinical Find

Frontiers in Neurology, 2020
Myasthenia gravis (MG) is an uncommon autoimmune neuromuscular junction disorder manifesting as fluctuating weakness of skeletal muscles. To add to its repertoire of mimicking a wide range of neurological disorders, the present case report is, to the ...
Marwa Elnazeir, Siddharth Narayanan, Pradeepthi Badugu, Abid Hussain, Tamour Tareen, Alexi R. Hernandez, Wei Liu, Adriana E. Palade, Martin E. Brown   +8 more
doaj   +1 more source

Involvement of Acetylcholine Receptors in Cholinergic Pathway-Mediated Protection Against Autoimmune Diabetes

Frontiers in Immunology, 2019
Type I diabetes (T1D) is a T cell-driven autoimmune disease that results in the killing of pancreatic β-cells and, consequently, loss of insulin production.
Maria J. Fernández-Cabezudo, Junu A. George, Ghada Bashir, Yassir A. Mohamed, Alreem Al-Mansori, Mohammed M. Qureshi, Dietrich E. Lorke, Georg Petroianu, Basel K. al-Ramadi, Basel K. al-Ramadi   +9 more
doaj   +1 more source

Coordination of opposing sex-specific and core muscle groups regulates male tail posture during Caenorhabditis elegans male mating behavior [PDF]

, 2009
Background To survive and reproduce, animals must be able to modify their motor behavior in response to changes in the environment. We studied a complex behavior of Caenorhabditis elegans, male mating behavior, which provided a model for understanding ...
A Barrios, A Jones, A Jones, AA Beg, Allyson J Whittaker, BA Bamber, BB Wang, BJ Dickinson, C Loer, C Trent, D Weinshenker, DM Raizen, E Culetto, EM Gabriel, G Schindelman, H Ogawa, I Bany, I Putrenko, J Lewis, J Rand, J Richmond, J Srinivasan, J Sulston, J Sze, J White, JQ White, JT Fleming, K Liu, L Carnell, L Garcia, LE Waggoner, M Zhang, MM Francis, O Saifee, P Towers, Paul W Sternberg, RE Ritzmann, S Brenner, S Clark, SH Chalasani, SL McIntire, T Liu, W Schafer, Y Jin, Y Jin, Y Liu   +45 more
core   +3 more sources

Differential sensitivity of basal and acetylcholine-induced activity of nitric oxide to blockade by asymmetric dimethylarginine (ADMA) in the rat aorta [PDF]

, 2010
<b>Background and purpose</b>: Previous work has shown that NG-monomethyl-l-arginine (l-NMMA) paradoxically inhibits basal, but not ACh-stimulated activity of nitric oxide in rat aorta.
Archer, Boger, Cocks, De Gennaro Colonna, Dora, Dudzinski, Feng, Fleming, Frew, Fulton, Gallis, Hobbs, Jackson, Jin, Leiper, Liu, Martin, Martin, Miller, Moore, Olken, Overend, Palmer, Rapoport, Rees, Rees, Siroen, Vallance, Vallance, Vladimirova-Kitova   +29 more
core   +2 more sources

Cholinergic Modulation of Cortical Microcircuits Is Layer-Specific: Evidence from Rodent, Monkey and Human Brain

Frontiers in Neural Circuits, 2017
Acetylcholine (ACh) signaling shapes neuronal circuit development and underlies specific aspects of cognitive functions and behaviors, including attention, learning, memory and motivation.
Joshua Obermayer, Matthijs B. Verhoog, Antonio Luchicchi, Huibert D. Mansvelder   +3 more
doaj   +1 more source

Cholinergic Pathway SNPs and Postural Control in 477 Older Adults

Frontiers in Aging Neuroscience, 2018
Objective: To determine whether single nucleotide polymorphisms (SNPs) of the cholinergic system and quantitative parameters of postural control are associated in healthy older adults.
Carina Arnold, Carina Arnold, Claudia Schulte, Claudia Schulte, Mariana Moscovich, Ulrike Sünkel, Ulrike Sünkel, Laura Zaunbrecher, Laura Zaunbrecher, Florian Metzger, Florian Metzger, Thomas Gasser, Thomas Gasser, Gerhard W. Eschweiler, Gerhard W. Eschweiler, Ann-Kathrin Hauser, Ann-Kathrin Hauser, Daniela Berg, Daniela Berg, Daniela Berg, Walter Maetzler, Walter Maetzler, Walter Maetzler   +22 more
doaj   +1 more source

Loss of GABA co-transmission from cholinergic neurons impairs behaviors related to hippocampal, striatal, and medial prefrontal cortex functions

Frontiers in Behavioral Neuroscience, 2022
Introduction: Altered signaling or function of acetylcholine (ACh) has been reported in various neurological diseases, including Alzheimer’s disease, Tourette syndrome, epilepsy among others.
R. Oliver Goral, R. Oliver Goral, Kathryn M. Harper, Briana J. Bernstein, Briana J. Bernstein, Sydney A. Fry, Sydney A. Fry, Patricia W. Lamb, Sheryl S. Moy, Jesse D. Cushman, Jesse D. Cushman, Jerrel L. Yakel   +11 more
doaj   +1 more source

An in vivo biosensor for neurotransmitter release and in situ receptor activity. [PDF]

, 2010
Tools from molecular biology, combined with in vivo optical imaging techniques, provide new mechanisms for noninvasively observing brain processes. Current approaches primarily probe cell-based variables, such as cytosolic calcium or membrane potential ...
Griesbeck, Oliver, Kleinfeld, David, Mank, Marco, Muller, Arnaud, Nguyen, Quoc-Thang, Schroeder, Lee F, Taylor, Palmer   +6 more
core   +2 more sources

Case report: Immune remission from generalized myasthenia gravis in a dog with a thymoma and cholangiocellular carcinoma

Frontiers in Veterinary Science, 2023
A 9-year-old male neutered Cockapoo was presented with an acute and progressive history of exercise induced weakness involving all limbs, and bilateral decreased ability to blink.
Thomas Mignan, Thomas Mignan, Robert White, Kimberley Stee, Giuseppe Bonanno, Mike Targett, Mark Lowrie   +6 more
doaj   +1 more source

A Microbioassay for Acetylcholine.

Experimental Biology and Medicine, 1961
SummaryA microbioassay for acetylcholine is described in which a solution containing acetylcholine is microperfused onto the endplate area of a chronically denervated skeletal muscle fiber. The endpoint, a brief tetanus, can be produced by application of as little as 0.15 μl of a solution which contains acetylcholine chloride at a concentration of 2.5 ×
William L. Nastuk, Leonard Levine
openaire   +3 more sources