Results 31 to 40 of about 69,146 (292)

Monoclonal antibodies against muscle actin isoforms: epitope identification and analysis of isoform expression by immunoblot and immunostaining in normal and regenerating skeletal muscle [version 2; referees: 3 approved]

open access: yesF1000Research, 2016
Higher vertebrates (mammals and birds) express six different highly conserved actin isoforms that can be classified in three subgroups: 1) sarcomeric actins, α-skeletal (α-SKA) and α-cardiac (α-CAA), 2) smooth muscle actins (SMAs), α-SMA and γ-SMA, and 3)
Christine Chaponnier, Giulio Gabbiani
doaj   +1 more source

Molecular characterization of three muscle alpha actin genes in mud loach (Misgurnus mizolepis; Cypriniformes)

open access: yesFisheries and Aquatic Sciences, 2017
Background Teleosts represent unique features in the regulation of muscle development and growth, with a great deal of myogenic plasticity. Muscle actins are major components to compose muscle fibers, and they play essential roles in cellular mobility ...
Sang Yoon Lee   +2 more
doaj   +1 more source

Actin in development

open access: yesMechanisms of Development, 2003
1. From molecules to morphologyMetazoan development is often viewed as a series ofinformation processing events in which the genomecomputes where and when to synthesize particular geneproducts. Importantly, development is also a feat ofengineering in which genetic information is used to changecell shape and cell–cell interactions to generate form ...
Buzz Baum, António Jacinto
openaire   +3 more sources

Novel Actin Cytoskeleton. Actin Tubules.

open access: yesCell Structure and Function, 2000
In spores of Dictyostelium discoideum three actin filaments are bundled to form a novel tubular structure and the tubules are then organized into rods. These tubular structures we will term actin tubules. Actin tubules are reconstructed from the supernatant of spore homogenates, while the usual actin filaments were bundled after incubation of ...
Masako Osumi   +4 more
openaire   +4 more sources

Actin in 2021 [PDF]

open access: yesCurrent Biology, 2021
Robert Insall introduces the cytoskeleton special issue and summarises some recent changes in our view of actin function and regulation.
openaire   +2 more sources

Actin cytoskeleton: Putting a CAP on actin polymerization [PDF]

open access: yesCurrent Biology, 2000
Two recent studies have identified a Drosophila homolog of cyclase-associated protein (CAP) as a developmentally important negative regulator of actin polymerization that may also directly mediate signal transduction.
Stevenson, Victoria A.   +1 more
openaire   +4 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

The mother of all actins?

open access: yeseLife, 2016
New insights into the structure of filaments made of crenactin, a homolog of actin found in archaea, shed light on how the cytoskeleton might have evolved.
Felipe Merino, Stefan Raunser
doaj   +1 more source

A method for rapidly screening functionality of actin mutants and tagged actins [PDF]

open access: yesBiological Procedures Online, 2004
Recombinant production and biochemical analysis of actin mutants has been hampered by the fact that actin has an absolute requirement for the eukaryotic chaperone CCT to reach its native state.
Rommelaere Heidi   +4 more
doaj   +1 more source

The Actin Cytoskeleton and Actin-Based Motility [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2018
The actin cytoskeleton-a collection of actin filaments with their accessory and regulatory proteins-is the primary force-generating machinery in the cell. It can produce pushing (protrusive) forces through coordinated polymerization of multiple actin filaments or pulling (contractile) forces through sliding actin filaments along bipolar filaments of ...
openaire   +3 more sources

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