Results 31 to 40 of about 52,842 (247)
Infections with filamentous fungi are common to all animals, but attention is rising especially due to the increasing incidence and high mortality rates observed in immunocompromised human individuals. Here, Aspergillus fumigatus and other members of its
Silvia Novohradská+4 more
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Dictyostelium discoideum as a Model for Investigating Neurodegenerative Diseases
The social amoeba Dictyostelium discoideum is a model organism that is used to investigate many cellular processes including chemotaxis, cell motility, cell differentiation, and human disease pathogenesis.
Holly N. Haver+3 more
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Evolution of size and pattern in the social amoebas [PDF]
A fundamental goal of biology is to understand how novel phenotypes evolved through changes in existing genes. The Dictyostelia or social amoebas represent a simple form of multicellularity, where starving cells aggregate to build fruiting structures ...
Schaap, P.
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Development of a Positive Selection High Throughput Genetic Screen in Dictyostelium discoideum
The cellular slime mold Dictyostelium discoideum is a powerful model organism that can be utilized to investigate human health and disease. One particular strength of Dictyostelium is that it can be utilized for high throughput genetic screens.
Felicia N. Williams+4 more
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MAPKs in development: insights from Dictyostelium signaling pathways
Mitogen activated protein kinases (MAPKs) play important roles in the development of eukaryotic organisms through the regulation of signal transduction pathways stimulated by external signals.
Hadwiger Jeffrey A., Nguyen Hoai-Nghia
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Localization of actin in Dictyostelium amebas by immunofluorescence [PDF]
Antibody prepared against avian smooth muscle actin has been used to localize actin in the slime mold, Dictyostelium discoideum. The distribution of actin in migrating cells is different from that in feeding cells.
Eckert, Barry S., Lazarides, Elias
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Lysosomes appear as the auto-fluorescent vacuoles in Dictyostelium discoideum cells
Dictyostelium discoideum cells contain auto-fluorescent vacuoles. To determine the identity of these vacuoles, the fluorescent dye 4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole (NBD-PZ) was used to stain the lysosomes in D. discoideum cells. Neither the
Kainuma Hiroki+4 more
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Fate and regulation of anterior-like cells in Dictyostelium slugs [PDF]
A pattern of two tissue types exists in the Dictyostelium slug. Contained within the posterior tissue are anterior-like cells which comprise about 10% of the developing cell mass.
David, Charles N., Sternfeld, John
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Inference of the drivers of collective movement in two cell types: Dictyostelium and melanoma [PDF]
Collective cell movement is a key component of many important biological processes, including wound healing, the immune response and the spread of cancers.
Ferguson, Elaine A.+3 more
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Extracellular signaling in Dictyostelium
In the last few decades, we have learned a considerable amount about how eukaryotic cells communicate with each other, and what it is the cells are telling each other. The simplicity of Dictyostelium discoideum, and the wide variety of available tools to study this organism, makes it the equivalent of a hydrogen atom for cell and developmental biology.
Sara A. Kirolos+5 more
openaire +4 more sources