Results 31 to 40 of about 427,116 (292)

Interleukin-10 Attenuates Liver Fibrosis Exacerbated by Thermoneutrality

Frontiers in Medicine, 2021
Background: Crosstalk between brown adipose tissue (BAT) and the liver is receiving increasing attention. This study investigated the effect of BAT dysfunction by thermoneutral (TN) housing on liver fibrosis in mice and examined the effect of secreted ...
Ha Thi Nga, Ha Thi Nga, Ha Thi Nga, Ji Sun Moon, Ji Sun Moon, Ji Sun Moon, Jingwen Tian, Jingwen Tian, Jingwen Tian, Ho Yeop Lee, Ho Yeop Lee, Ho Yeop Lee, Seok-Hwan Kim, Young-Sun Lee, Jae-Han Jeon, Hyon-Seung Yi, Hyon-Seung Yi, Hyon-Seung Yi   +17 more
doaj   +1 more source

Endocrine FGFs: evolution, physiology, pathophysiology, and pharmacotherapy

Frontiers in Endocrinology, 2015
The human fibroblast growth factor (FGF) family comprises 22 structurally related polypeptides that play crucial roles in neuronal functions, development, and metabolism.
Nobuyuki eItoh, Hiroya eOhta, Morichika eKonishi   +2 more
doaj   +1 more source

Can one die because of Hashimoto’s disease? – a clinical review of diagnosis, clinical features and treatment of myxedema coma

Quality in Sport
Introduction and Purpose Hashimoto’s disease is the most common reason of hypothyroidism. Usually, it is easy to recognize and treat. However, under certain circumstances, it may develop into the most severe manifestation of hypothyroidism known as ...
Karol Bochyński, Michał Dacka, Kamila Giżewska, Konrad Białogłowski, Paulina Dąbrowska, Michał Żuber, Katarzyna Ciuba, Katarzyna Molenda, Filip Borodziuk, Barbara Borodziuk   +9 more
doaj   +1 more source

Endocrine pathologies in the conditions of chemotherapy

Infusion & Chemotherapy, 2023
BACKGROUND. Cancer is the leading cause of death in the world. Chemotherapy is the most effective and in some cases the only method of treating oncopathology.
A.V. Garnytska, O.S. Orlyk
doaj   +1 more source

Initial experience of dedicated breast PET imaging of ER+ breast cancers using [F-18]fluoroestradiol. [PDF]

, 2019
Dedicated breast positron emission tomography (dbPET) is an emerging technology with high sensitivity and spatial resolution that enables detection of sub-centimeter lesions and depiction of intratumoral heterogeneity.
Chien, Amy J, Esserman, Laura J, Franc, Benjamin L, Hylton, Nola M, Joe, Bonnie N, Jones, Ella F, Li, Wen, Mukhtar, Rita A, Pampaloni, Miguel H, Ray, Kimberly M, Seo, Youngho   +10 more
core   +2 more sources

Thyroid Hormone Availability and Action during Brain Development in Rodents

Frontiers in Cellular Neuroscience, 2017
Thyroid hormones (THs) play an essential role in the development of all vertebrates; in particular adequate TH content is crucial for proper neurodevelopment.
Soledad Bárez-López, Soledad Bárez-López, Ana Guadaño-Ferraz, Ana Guadaño-Ferraz   +3 more
doaj   +1 more source

A Novel Mutation in the Upstream Open Reading Frame of the CDKN1B Gene Causes a MEN4 Phenotype [PDF]

, 2013
PubMed ID: 23555276This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Borriello, A Falchetti, A Mehta, A Ozawa, A Wiestner, A Yoon, Alessandro Quattrone, BG Luukkonen, C Le Sage, Carla Scaroni, CC Spevak, CJ Sherr, CJ Sherr, D Malanga, Daniela Regazzo, Denis Ciato, DR Morris, Elena Pardi, Filomena Cetani, Francesca Boaretto, Franco Mantero, G Beffagna, G Johannes, G Occhi, GC Scheper, Giampaolo Trivellin, Gianluca Occhi, Giuseppe Opocher, IM Chu, J Costa-Guda, J Slingerland, K Wethmar, L Liu, L Quintanilla-Martinez, M Georgitsi, M Kozak, M Kozak, M Kullmann, M Matsui, Marshall S. Horwitz, MD Larrea, ML Crowe, ML Fero, Márta Korbonits, Natalia S. Pellegata, NS Pellegata, P Chomczynski, RV Thakker, S Igreja, S Molatore, S Ye, Sara Bobisse, SE Calvo, Sergio Ferasin, SI Reed, SK Agarwal, U Göpfert, Viktoryia Sidarovich, W Zhou, WK Miskimins, Y Wen   +60 more
core   +3 more sources

Targeting trafficking as a therapeutic avenue for misfolded GPCRs leading to endocrine diseases

Frontiers in Endocrinology, 2022
G protein-coupled receptors (GPCRs) are plasma membrane proteins associated with an array of functions. Mutations in these receptors lead to a number of genetic diseases, including diseases involving the endocrine system.
Alfredo Ulloa-Aguirre, Teresa Zariñán, Rubén Gutiérrez-Sagal, Ya-Xiong Tao   +3 more
doaj   +1 more source

Ligula intestinalis (Cestoda: Pseudophyllidea): an ideal fish-metazoan parasite model? [PDF]

, 2010
Since its use as a model to study metazoan parasite culture and in vitro development, the plerocercoid of the tapeworm, Ligula intestinalis, has served as a useful scientific tool to study a range of biological factors, particularly within its fish ...
Carter, V, Dufour, S, Hoole, D
core   +1 more source

Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]

, 2017
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core   +2 more sources