Results 31 to 40 of about 876,771 (208)

Immune Checkpoint Inhibitors and Endocrine Disorders: A Position Statement from the Korean Endocrine Society [PDF]

Endocrinology and Metabolism, 2022
Immune checkpoint inhibitors (ICIs) including an anti-cytotoxic T-lymphocyte-associated antigen 4 inhibitor, anti-programmed cell death protein 1 (PD-1) inhibitors, and anti-PD-ligand 1 inhibitors are representative therapeutics for various malignancies.
Hyemi Kwon, Eun Roh, Chang Ho Ahn, Hee Kyung Kim, Cheol Ryong Ku, Kyong Yeun Jung, Ju Hee Lee, Eun Heui Kim, Sunghwan Suh, Sangmo Hong, Jeonghoon Ha, Jun Sung Moon, Jin Hwa Kim, Mi-kyung Kim,   +14 more
doaj   +1 more source

An analysis of $\mathbb{P}$-invariance and dynamical compensation properties from a control perspective [PDF]

BMC Bioinformatics. 25.1 (2024): 95, 2023
Dynamical compensation (DC) provides robustness to parameter fluctuations. As an example, DC enable control of the functional mass of endocrine or neuronal tissue essential for controlling blood glucose by insulin through a nonlinear feedback loop. Researchers have shown that DC is related to structural unidentifiability and $\mathbb{P}$-invariance ...
arxiv   +1 more source

EPA’s Endocrine Disruptor Screening Program (EDSP)

EDIS, 2013
People have asked questions in recent years concerning the effects that certain chemicals may have on the endocrine system of humans and wildlife. Laboratory studies have produced evidence that show various chemicals disrupt the endocrine systems of ...
Frederick M. Fishel
doaj   +5 more sources

Which papillary thyroid microcarcinoma should be treated as “true cancer” and which as “precancer”?

World Journal of Surgical Oncology, 2019
Background Papillary thyroid microcarcinoma (PTMC) generally is a cancer with excellent prognosis, but the term “cancer” sounds severe and harsh, which can elicit emotional and physical responses from patients.
Krzysztof Kaliszewski, Dorota Diakowska, Beata Wojtczak, Zdzisław Forkasiewicz, Dominika Pupka, Łukasz Nowak, Jerzy Rudnicki   +6 more
doaj   +1 more source

Roles of osteoprotegerin in endocrine and metabolic disorders through receptor activator of nuclear factor kappa-B ligand/receptor activator of nuclear factor kappa-B signaling

Frontiers in Cell and Developmental Biology, 2022
Endocrine and metabolic diseases show increasing incidence and high treatment costs worldwide. Due to the complexity of their etiology and mechanism, therapeutic strategies are still lacking.
Luodan Zhang, Fa Zeng, Minmin Jiang, Minmin Jiang, Maozhen Han, Binbin Huang   +5 more
doaj   +1 more source

Interleukin-10 Attenuates Liver Fibrosis Exacerbated by Thermoneutrality

Frontiers in Medicine, 2021
Background: Crosstalk between brown adipose tissue (BAT) and the liver is receiving increasing attention. This study investigated the effect of BAT dysfunction by thermoneutral (TN) housing on liver fibrosis in mice and examined the effect of secreted ...
Ha Thi Nga, Ha Thi Nga, Ha Thi Nga, Ji Sun Moon, Ji Sun Moon, Ji Sun Moon, Jingwen Tian, Jingwen Tian, Jingwen Tian, Ho Yeop Lee, Ho Yeop Lee, Ho Yeop Lee, Seok-Hwan Kim, Young-Sun Lee, Jae-Han Jeon, Hyon-Seung Yi, Hyon-Seung Yi, Hyon-Seung Yi   +17 more
doaj   +1 more source

Endocrine pathologies in the conditions of chemotherapy

Infusion & Chemotherapy, 2023
BACKGROUND. Cancer is the leading cause of death in the world. Chemotherapy is the most effective and in some cases the only method of treating oncopathology.
A.V. Garnytska, O.S. Orlyk
doaj   +1 more source

Diagnostic algorithm in combined surgical pathology in patients with diseases of endocrine system

Mìžnarodnij Endokrinologìčnij Žurnal, 2017
Background. Every 2 years, the incidence of endocrine pathology increased by 23–30 %. During the diagnostic search, 25–30 % of patients with endocrine disorders appear to have 2 to 4 combined surgical diseases.
S.M. Zavgorodniy, M.A. Kubrak, A.I. Rylov, M.B. Danilyk   +3 more
doaj   +1 more source

Can one die because of Hashimoto’s disease? – a clinical review of diagnosis, clinical features and treatment of myxedema coma

Quality in Sport
Introduction and Purpose Hashimoto’s disease is the most common reason of hypothyroidism. Usually, it is easy to recognize and treat. However, under certain circumstances, it may develop into the most severe manifestation of hypothyroidism known as ...
Karol Bochyński, Michał Dacka, Kamila Giżewska, Konrad Białogłowski, Paulina Dąbrowska, Michał Żuber, Katarzyna Ciuba, Katarzyna Molenda, Filip Borodziuk, Barbara Borodziuk   +9 more
doaj   +1 more source

Methodical approaches to managing risks for endocrine diseases evolvement in children related to impacts of environmental factors occuring on areas aimed for development

Analiz Riska Zdorovʹû, 2017
It is vital to develop systems of preventing risk-associated pathology due to constantly high levels of endocrine diseases in children exposed to chemicals with trophic effects on endocrine system (lead, cadmium, manganese, chromium, nickel, benzene ...
K.P. Luzhetskiy
doaj   +1 more source