Results 31 to 40 of about 5,373 (162)
Hfq mutation confers increased cephalosporin resistance in Klebsiella pneumoniae [PDF]
Archives of Biological Sciences, 2017 Klebsiella pneumoniae (K. pneumoniae), is an opportunistic pathogen raising significant public health concerns owing to its multi-drug resistance. Hfq, one of the main RNA-binding proteins, is a key post-transcriptional regulator.
Li Xinran +7 more
doaj +1 more source
Models of Hfq interactions with small non-coding RNA in Gram-negative and Gram-positive bacteria
Frontiers in Cellular and Infection Microbiology, 2023 Hfq is required by many Gram-negative bacteria to chaperone the interaction between small non-coding RNA (sRNA) and mRNA to facilitate annealing. Conversely and despite the presence of Hfq in many Gram-positive bacteria, sRNAs in Gram-positive bacteria ...
Derrick Watkins, Dev Arya
doaj +1 more source
Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions
Angewandte Chemie, EarlyView.This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan +3 more
wiley +2 more sources
Functional Characterization of Acinetobacter baumannii Lacking the RNA Chaperone Hfq
Frontiers in Microbiology, 2017 The RNA chaperone Hfq is involved in the riboregulation of diverse genes via small RNAs. Recent studies have demonstrated that Hfq contributes to the stress response and the virulence of several pathogens, and the roles of Hfq vary among bacterial ...
Han-Yueh Kuo +9 more
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Tracking the Elusive Function of Bacillus subtilis Hfq.
PLoS ONE, 2015 RNA-binding protein Hfq is a key component of the adaptive responses of many proteobacterial species including Escherichia coli, Salmonella enterica and Vibrio cholera.
Tatiana Rochat +6 more
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The Pseudomonas aeruginosa CrcZ RNA interferes with Hfq-mediated riboregulation.
PLoS ONE, 2017 The RNA chaperone Hfq regulates virulence and metabolism in the opportunistic pathogen Pseudomonas aeruginosa. During carbon catabolite repression (CCR) Hfq together with the catabolite repression control protein Crc can act as a translational repressor ...
Elisabeth Sonnleitner +2 more
doaj +1 more source
The Pleiotropic Phenotypes Caused by an hfq Null Mutation in Vibrio harveyi
Microorganisms, 2023 Hfq is a global regulator and can be involved in multiple cellular processes by assisting small regulatory RNAs (sRNAs) to target mRNAs. To gain insight into the virulence regulation of Hfq in Vibrio harveyi, the hfq null mutant, ∆hfq, was constructed in
Yiqin Deng +5 more
doaj +1 more source
Communications Biology, 2023 Hfq is a pleitropic actor that serves as stress response and virulence factor in the bacterial cell. To execute its multiple functions, Hfq assembles into symmetric torus-shaped hexamers.
Mélanie Berbon +8 more
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The Escherichia coli Hfq protein: an unattended DNA-transactions regulator
Frontiers in Molecular Biosciences, 2016 The Hfq protein was discovered in Escherichia coli as a host factor for bacteriophage Qβ RNA replication. Subsequent studies indicated that Hfq is a pleiotropic regulator of bacterial gene expression.
Grzegorz M Cech +6 more
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Association of RNAs with Bacillus subtilis Hfq. [PDF]
PLoS ONE, 2013 The prevalence and characteristics of small regulatory RNAs (sRNAs) have not been well characterized for Bacillus subtilis, an important model system for Gram-positive bacteria. However, B.
Michael Dambach +2 more
doaj +1 more source