Results 1 to 10 of about 92,611 (279)
Structural basis of rotavirus RNA chaperone displacement and RNA annealing. [PDF]
Proc Natl Acad Sci U S A, 2021 Significance Accurate RNA folding is essential for virus replication. Rotaviruses are viruses infecting humans and animals. Rotavirus genome comprises 11 distinct RNAs, and successful replication requires the incorporation of all 11 RNAs into a virion.
Bravo JPK +10 more
europepmc +8 more sources
Coronavirus nucleocapsid protein is an RNA chaperone
Virology, 2007 RNA chaperones are nonspecific nucleic acid binding proteins with long disordered regions that help RNA molecules to adopt its functional conformation. Coronavirus nucleoproteins (N) are nonspecific RNA-binding proteins with long disordered regions. Therefore, we investigated whether transmissible gastroenteritis coronavirus (TGEV) N protein was an RNA
Sonia Zuniga +2 more
exaly +4 more sources
RNA Biology, 2022 In all domains of life, RNA chaperones safeguard and guide the fate of the cellular RNA pool. RNA chaperones comprise structurally diverse proteins that ensure proper folding, stability, and ribonuclease resistance of RNA, and they support regulatory ...
Kai Katsuya-Gaviria +2 more
exaly +5 more sources
RNA can function as molecular chaperone for RNA folding
Giant, 2020 RNAs can mimic the information storage, replication and catalysis functions of DNAs and proteins, providing physical evidence for the widely accepted RNA world hypothesis that RNA alone constitutes earlier life forms.
Zhi-Chao Lei +2 more
exaly +4 more sources
CISP, an Intrinsically Disordered Cold‐Inducible Barley Protein, Functions as a Small RNA Chaperone [PDF]
Plant DirectLow temperatures are a major environmental stress that limits plant growth and development. Understanding the molecular mechanism of cold tolerance is therefore essential for improving crop performance through molecular breeding.
Yutaro Okumura +2 more
doaj +2 more sources
Structural and functional analysis of a plant nucleolar RNA chaperone-like protein [PDF]
Scientific Reports, 2023 Ribosome biogenesis is a key process in all eukaryotic cells that requires hundreds of ribosome biogenesis factors (RBFs), which are essential to build the mature ribosomes consisting of proteins and rRNAs.
Rita Fernandes +8 more
doaj +2 more sources
The DEAD-box helicase eIF4A1/2 acts as RNA chaperone during mitotic exit enabling chromatin decondensation [PDF]
Nature CommunicationsDuring mitosis, chromosomes condense and decondense to segregate faithfully and undamaged. The exact molecular mechanisms are not well understood. We identify the DEAD-box helicase eIF4A1/2 as a critical factor in this process.
Ramona Jühlen +15 more
doaj +2 more sources
The archaeal RNA chaperone TRAM0076 shapes the transcriptome and optimizes the growth of Methanococcus maripaludis. [PDF]
PLoS Genetics, 2019 TRAM is a conserved domain among RNA modification proteins that are widely distributed in various organisms. In Archaea, TRAM occurs frequently as a standalone protein with in vitro RNA chaperone activity; however, its biological significance and ...
Jie Li +8 more
doaj +2 more sources
Lipid vesicles chaperone an encapsulated RNA aptamer [PDF]
Nature Communications, 2018 So far little is known about how encapsulation affects the activity and folding of RNA, which is of interest for understanding the origin of cellular life.
Ranajay Saha +2 more
doaj +5 more sources
Light-Triggered RNA Annealing by an RNA Chaperone. [PDF]
Angew Chem Int Ed Engl, 2015 AbstractNon‐coding antisense RNAs regulate bacterial genes in response to nutrition or environmental stress, and can be engineered for artificial gene control. The RNA chaperone Hfq accelerates antisense pairing between non‐coding RNAs and their mRNA targets, by a mechanism still unknown.
Panja S +3 more
europepmc +4 more sources