Results 31 to 40 of about 902,633 (284)
Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres [PDF]
A number of studies have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many cell types including skeletal muscle fibres.
Dietmar Steverding +8 more
core +1 more source
Duchenne muscular dystrophy (DMD) is caused by the lack of dystrophin, a cytoskeletal protein essential for the preservation of the structural integrity of the muscle cell membrane.
Dongwoo Hahn +6 more
doaj +1 more source
The likely effects of thermal climate change on vertebrate skeletal muscle mechanics with possible consequences for animal movement and behaviour [PDF]
Climate change can involve alteration in the local temperature that an animal is exposed to, which in turn may affect skeletal muscle temperature.
Abrahams +100 more
core +1 more source
HDAC4 regulates skeletal muscle regeneration via soluble factors [PDF]
Skeletal muscle possesses a high ability to regenerate after an insult or in pathological conditions, relying on satellite cells, the skeletal muscle stem cells.
Alessandra Renzini +5 more
core +3 more sources
Background Nuclear bodies, such as nucleoli, PML bodies, and SC35 speckles, are dynamic sub-nuclear structures that regulate multiple genetic and epigenetic processes. Additional regulation is provided by RNA/DNA handling proteins, notably TDP-43 and FUS,
Sachiko Homma +4 more
doaj +1 more source
Skeletal muscle as an experimental model of choice to study tissue aging and rejuvenation. [PDF]
Skeletal muscle is among the most age-sensitive tissues in mammal organisms. Significant changes in its resident stem cells (i.e., satellite cells, SCs), differentiated cells (i.e., myofibers), and extracellular matrix cause a decline in tissue ...
Conboy, Irina M +4 more
core
RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assays. [PDF]
Elevated cytoplasmic [Ca2+] is characteristic in severe skeletal and cardiac myopathies, diabetes, and neurodegeneration, and partly results from increased Ca2+ leak from sarcoplasmic reticulum stores via dysregulated ryanodine receptor (RyR) channels ...
Bers, Donald M +6 more
core +2 more sources
IndroductionBioelectrical Impedance Analysis (BIA) is a widely used method to assess body composition. Traditional BIA models use predictive equations without considering individual characteristics such as age, sex, and activity level.
Ismael Figueiredo Rabelo +7 more
doaj +1 more source
Background Osteopontin is secreted by skeletal muscle myoblasts and macrophages, and its expression is upregulated in muscle following injury. Osteopontin is present in many different structural forms, which vary in their expression patterns and effects ...
Dimuthu K. Wasgewatte Wijesinghe +2 more
doaj +1 more source
Evaluation of skeletal muscle frequently combines morphologic and morphometric techniques. As is the case with many organ systems, skeletal muscle has limited responses to insult or injury. Over the past several years, crucial interactions between skeletal muscle, bone, and the nervous system have been described.
openaire +2 more sources

