Results 31 to 40 of about 902,633 (284)

Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres [PDF]

open access: yes, 2015
A number of studies have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many cell types including skeletal muscle fibres.
Dietmar Steverding   +8 more
core   +1 more source

Rapid restitution of contractile dysfunction by synthetic copolymers in dystrophin-deficient single live skeletal muscle fibers

open access: yesSkeletal Muscle, 2023
Duchenne muscular dystrophy (DMD) is caused by the lack of dystrophin, a cytoskeletal protein essential for the preservation of the structural integrity of the muscle cell membrane.
Dongwoo Hahn   +6 more
doaj   +1 more source

The likely effects of thermal climate change on vertebrate skeletal muscle mechanics with possible consequences for animal movement and behaviour [PDF]

open access: yes, 2019
Climate change can involve alteration in the local temperature that an animal is exposed to, which in turn may affect skeletal muscle temperature.
Abrahams   +100 more
core   +1 more source

HDAC4 regulates skeletal muscle regeneration via soluble factors [PDF]

open access: yes, 2018
Skeletal muscle possesses a high ability to regenerate after an insult or in pathological conditions, relying on satellite cells, the skeletal muscle stem cells.
Alessandra Renzini   +5 more
core   +3 more sources

Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4

open access: yesSkeletal Muscle, 2016
Background Nuclear bodies, such as nucleoli, PML bodies, and SC35 speckles, are dynamic sub-nuclear structures that regulate multiple genetic and epigenetic processes. Additional regulation is provided by RNA/DNA handling proteins, notably TDP-43 and FUS,
Sachiko Homma   +4 more
doaj   +1 more source

Skeletal muscle as an experimental model of choice to study tissue aging and rejuvenation. [PDF]

open access: yes, 2020
Skeletal muscle is among the most age-sensitive tissues in mammal organisms. Significant changes in its resident stem cells (i.e., satellite cells, SCs), differentiated cells (i.e., myofibers), and extracellular matrix cause a decline in tissue ...
Conboy, Irina M   +4 more
core  

RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assays. [PDF]

open access: yes, 2020
Elevated cytoplasmic [Ca2+] is characteristic in severe skeletal and cardiac myopathies, diabetes, and neurodegeneration, and partly results from increased Ca2+ leak from sarcoplasmic reticulum stores via dysregulated ryanodine receptor (RyR) channels ...
Bers, Donald M   +6 more
core   +2 more sources

Bioelectrical impedance vectors analysis (BIVA) in older adults according to level of physical activity and muscle strength: a comparison of classic and specific approaches

open access: yesFrontiers in Aging
IndroductionBioelectrical Impedance Analysis (BIA) is a widely used method to assess body composition. Traditional BIA models use predictive equations without considering individual characteristics such as age, sex, and activity level.
Ismael Figueiredo Rabelo   +7 more
doaj   +1 more source

Normal inflammation and regeneration of muscle following injury require osteopontin from both muscle and non-muscle cells

open access: yesSkeletal Muscle, 2019
Background Osteopontin is secreted by skeletal muscle myoblasts and macrophages, and its expression is upregulated in muscle following injury. Osteopontin is present in many different structural forms, which vary in their expression patterns and effects ...
Dimuthu K. Wasgewatte Wijesinghe   +2 more
doaj   +1 more source

Skeletal Muscle Toolbox [PDF]

open access: yesToxicologic Pathology, 2017
Evaluation of skeletal muscle frequently combines morphologic and morphometric techniques. As is the case with many organ systems, skeletal muscle has limited responses to insult or injury. Over the past several years, crucial interactions between skeletal muscle, bone, and the nervous system have been described.
openaire   +2 more sources

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