Results 31 to 40 of about 1,321,604 (332)

GeSeq – versatile and accurate annotation of organelle genomes

open access: yesNucleic Acids Res., 2017
We have developed the web application GeSeq (https://chlorobox.mpimp-golm.mpg.de/geseq.html) for the rapid and accurate annotation of organellar genome sequences, in particular chloroplast genomes.
Michael Tillich   +6 more
semanticscholar   +1 more source

Chaperones and Proteostasis: Role in Parkinson’s Disease

open access: yesDiseases, 2020
Proper folding to attain a defined three-dimensional structure is a prerequisite for the functionality of a protein. Improper folding that eventually leads to formation of protein aggregates is a hallmark of several neurodegenerative disorders.
Neha Joshi   +2 more
doaj   +1 more source

Kinesin Light Chains Are Essential for Axonal Transport in Drosophila [PDF]

open access: yes, 1998
Kinesin is a heterotetramer composed of two 115-kD heavy chains and two 58-kD light chains. The microtubule motor activity of kinesin is performed by the heavy chains, but the functions of the light chains are poorly understood.
Beushausen, Sven   +4 more
core   +2 more sources

ER proteins decipher the tubulin code to regulate organelle distribution

open access: yesNature, 2021
Organelles move along differentially modified microtubules to establish and maintain their proper distributions and functions 1 , 2 . However, how cells interpret these post-translational microtubule modification codes to selectively regulate organelle ...
P. Zheng   +7 more
semanticscholar   +1 more source

The Complete Mitochondrial Genome of a Neglected Breed, the Peruvian Creole Cattle (Bos taurus), and Its Phylogenetic Analysis

open access: yesData, 2022
Cattle spread throughout the American continent during the colonization years, originating creole breeds that adapted to a wide range of climate conditions.
Carlos I. Arbizu   +8 more
doaj   +1 more source

Protein import into the endosymbiotic organelles of apicomplexan parasites [PDF]

open access: yes, 2018
The organelles of endosymbiotic origin, plastids, and mitochondria, evolved through the serial acquisition of endosymbionts by a host cell. These events were accompanied by gene transfer from the symbionts to the host, resulting in most of the organellar
Fellows, Justin   +3 more
core   +1 more source

Mitochondrial quality control: from molecule to organelle

open access: yesCellular and Molecular Life Sciences, 2021
Mitochondria are organelles central to myriad cellular processes. To maintain mitochondrial health, various processes co-operate at both the molecular and organelle level. At the molecular level, mitochondria can sense imbalances in their homeostasis and
Alba Roca-Portoles, S. Tait
semanticscholar   +1 more source

The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy

open access: yesNature Communications, 2016
Autophagosome biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. Here Rao et al. use a reconstituted in vitrosystem to describe the mechanism by which activation of the Atg1-kinase complex from its constituent parts ...
Yijian Rao   +4 more
doaj   +1 more source

Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis [PDF]

open access: yes, 2004
A dynamic balance of organelle fusion and fission regulates mitochondrial morphology. During apoptosis this balance is altered, leading to an extensive fragmentation of the mitochondria.
Arnoult, Damien   +5 more
core   +2 more sources

Membrane Lipid Composition: Effect on Membrane and Organelle Structure, Function and Compartmentalization and Therapeutic Avenues

open access: yesInternational Journal of Molecular Sciences, 2019
Biological membranes are key elements for the maintenance of cell architecture and physiology. Beyond a pure barrier separating the inner space of the cell from the outer, the plasma membrane is a scaffold and player in cell-to-cell communication and the
Doralicia Casares   +2 more
semanticscholar   +1 more source

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