Results 31 to 40 of about 9,774,870 (350)

The role of PAF in immunopathology: From immediate hypersensitivity reactions to fungal defense

BioFactors, Volume 48, Issue 6, Page 1217-1225, November/December 2022., 2022
Abstract Platelet‐activating factor (PAF, 1‐alkyl‐2‐acetyl‐sn‐glycero‐3‐phosphorylcholine) was discovered when the mechanisms involved in the deposition of immune complex in tissues were being scrutinized in the experimental model of rabbit serum sickness.
Mariano Sánchez Crespo, Olimpio Montero, Nieves Fernandez   +2 more
wiley   +1 more source

Molecular simulation-based evaluation of anti-inflammatory properties of natural compounds derived from tobacco (Nicotiana tabacum L.): Computational multi-target approaches [PDF]

Pharmacia
Various components of the tobacco plant (Nicotiana tabacum L.) have undergone pharmacological assessment to highlight their traditional role in addressing different health conditions.
Vinda Maharani Patricia, Aulia Fikri Hidayat, Taufik Muhammad Fakih   +2 more
doaj   +3 more sources

Effects of benzene, quercetin, and their combination on porcine ovarian cell proliferation, apoptosis, and hormone release [PDF]

Archives Animal Breeding, 2019
We hypothesized that the environmental contaminant benzene and the plant antioxidant quercetin may affect ovarian cell functions and that quercetin could offer protection against the adverse effects of benzene.
A. Tarko, A. Štochmal'ová, K. Jedličková, S. Hrabovszká, A. Vachanová, A. H. Harrath, S. Alwasel, A. Alrezaki, J. Kotwica, A. Baláži, A. V. Sirotkin, A. V. Sirotkin   +11 more
doaj   +1 more source

Comprehensive Analysis of Prostaglandin Metabolic Enzyme Expression During Pregnancy and the Characterization of AKR1B1 as a Prostaglandin F Synthase at the Maternal-Conceptus Interface in Pigs1

Biology of Reproduction, 2014
Prostaglandins (PGs) are important lipid mediators regulating various reproductive processes in many species. In pigs, the expression pattern of PGE2 and PGF2α metabolic enzymes and the regulatory mechanism controlling PGE2 and PGF2α levels in the uterus
H. Seo, Yohan Choi, J. Shim, I. Yoo, H. Ka   +4 more
semanticscholar   +1 more source

Inhibitors of Oxidative Phosphorylation Modulate Astrocyte Inflammatory Responses through AMPK-Dependent Ptgs2 mRNA Stabilization

Cells, 2019
Inflammatory activation of astroglia adds to the pathology of various neurological diseases. Astrocytes respond to microglia-derived cytokines such as interleukin-1α (IL-1α) with enhanced inflammatory signaling.
Alina Astakhova, Dmitry Chistyakov, Dominique Thomas, Gerd Geisslinger, Bernhard Brüne, Marina Sergeeva, Dmitry Namgaladze   +6 more
doaj   +1 more source

Effects of prostaglandin F(2α) on adipocyte biology relevant to graves' orbitopathy.

Thyroid, 2013
BACKGROUND In Graves' orbitopathy (GO), increased proliferation, excess adipogenesis, and hyaluronan overproduction produce GO exophthalmos. Enophthalmos occurs in some glaucoma patients treated with Bimatoprost (prostaglandin F2α, PGF2α) eye drops.
M. Draman, F. Grennan-Jones, Lei Zhang, P. Taylor, T. K. Tun, J. McDermott, P. Moriarty, D. Morris, C. Lane, S. Sreenan, C. Dayan, M. Ludgate   +11 more
semanticscholar   +1 more source

Preparation of Prostaglandin F from Prostaglandin E. Prostaglandins and Related Factors. 6. [PDF]

Acta Chemica Scandinavica, 1962
Reduction of prostaglandin E (PGE) with sodium borohydride yielded 2 compounds 1 of which is identical with PGF isolated from the prostate of sheep and the other of which had different physical and biological properties but the same elementary composition. The former was designated PGF1 and the latter PGF2.
Olof Theander, Sune Bergström, Lennart Krabisch, Benny Samuelsson, H. Flood, J. Sjövall   +5 more
openaire   +2 more sources

Development of Potent and Selective Indomethacin Analogues for the Inhibition of AKR1C3 (Type 5 17β-Hydroxysteroid Dehydrogenase/Prostaglandin F Synthase) in Castrate-Resistant Prostate Cancer

Journal of Medicinal Chemistry, 2013
Castrate-resistant prostate cancer (CRPC) is a fatal, metastatic form of prostate cancer. CRPC is characterized by reactivation of the androgen axis due to changes in androgen receptor signaling and/or adaptive intratumoral androgen biosynthesis.
A. Liedtke, A. Adeniji, Mo Chen, Michael C. Byrns, Yi Jin, D. Christianson, L. Marnett, T. Penning   +7 more
semanticscholar   +1 more source

Effect of prostaglandin F2α &oxyotocin on semen charistrics of alawassi ram

Kufa Journal for Veterinary Medical Sciences, 2013
The study was conducted at the Faculty of Veterinary Medicine / University of Qadisiyah five Awassi Rams converged for the purpose of reconstruction see the effect of injection hormone prostaglandin F2α  and oxytocin in semen recipes for Awassisheep ...
Abdul Hussein Thyab Shoaibeth, Dhia Hussain Jassim Al-Dulamy   +1 more
doaj   +1 more source

Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin f(2α) impairs endothelial function in renovascular hypertensive rats.

Antioxidants and Redox Signaling, 2012
UNLABELLED Abstract Aims: The role of endothelium-derived contracting factors (EDCFs) in regulating renovascular function is yet to be elucidated in renovascular hypertension (RH).
X. Tian, W. Wong, F. Leung, Yang Zhang, Yi-xiang Wang, H. Lee, C. Ng, Z. Chen, X. Yao, C. Au, C. Lau, P. Vanhoutte, J. Cooke, Yu Huang   +13 more
semanticscholar   +1 more source