Results 31 to 40 of about 86,105 (313)

Prediction of Rivaroxaban-Rifampin Interaction After Major Orthopedic Surgery: Physiologically Based Pharmacokinetic Modeling and Simulation

Frontiers in Pharmacology, 2021
Rivaroxaban is commonly used for the prophylaxis of venous thromboembolism (VTE) for patients undergoing major orthopedic surgery. Rivaroxaban is primarily eliminated by hepatic CYP450 metabolism and renal excretion.
Rui-juan Xu, Rui-juan Xu, Tao Ling, Hong Tang, Wei-hong Ge, Qing Jiang   +5 more
doaj   +1 more source

Rapid molecular detection of tuberculosis and rifampin resistance.

New England Journal of Medicine, 2010
BACKGROUND Global control of tuberculosis is hampered by slow, insensitive diagnostic methods, particularly for the detection of drug-resistant forms and in patients with human immunodeficiency virus infection.
C. Boehme, P. Nabeta, D. Hillemann, M. Nicol, S. Shenai, F. Krapp, J. Allen, Rasim Tahirli, R. Blakemore, R. Rustomjee, A. Milovic, Martin Jones, S. M. O’Brien, D. Persing, S. Ruesch-Gerdes, E. Gotuzzo, C. Rodrigues, D. Alland, M. Perkins   +18 more
semanticscholar   +1 more source

Quantifying Isoniazid Levels in Small Hair Samples: A Novel Method for Assessing Adherence during the Treatment of Latent and Active Tuberculosis. [PDF]

, 2016
BackgroundTuberculosis (TB) is the leading cause of death from an infectious pathogen worldwide and the most prevalent opportunistic infection in people living with HIV.
Bacchetti, Peter, Chin, Aaron T, Gandhi, Monica, Gerona, Roy, Koss, Catherine A, Metcalfe, John, Wen, Anita   +6 more
core   +1 more source

The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing

mBio, 2017
The Xpert MTB/RIF assay (Xpert) is a rapid test for tuberculosis (TB) and rifampin resistance (RIF-R) suitable for point-of-care testing. However, it has decreased sensitivity in smear-negative sputum, and false identification of RIF-R occasionally ...
S. Chakravorty, A. Simmons, M. Rowneki, Heta Parmar, Yuan Cao, J. Ryan, P. Banada, Srinidhi Deshpande, S. Shenai, A. Gall, J. Glass, Barry Krieswirth, S. Schumacher, P. Nabeta, N. Tukvadze, C. Rodrigues, A. Skrahina, E. Tagliani, D. Cirillo, A. Davidow, C. Denkinger, D. Persing, R. Kwiatkowski, Martin Jones, D. Alland   +24 more
semanticscholar   +1 more source

Diagnosis and Interim Treatment Outcomes from the First Cohort of Multidrug-Resistant Tuberculosis Patients in Tanzania. [PDF]

, 2013
Kibong'oto National Tuberculosis Hospital (KNTH), Kilimanjaro, Tanzania. Characterize the diagnostic process and interim treatment outcomes from patients treated for multidrug-resistant tuberculosis (MDR-TB) in Tanzania.
Boeree, Martin J, Gratz, Jean, Heysell, Scott K, Houpt, Eric R, Kibiki, Gibson S, Kisonga, Riziki M, Kumburu, Happiness H, Lekule, Isack A, Mpagama, Stellah G, Ndusilo, Nora D   +9 more
core   +12 more sources

Recurrent Cutaneous Tuberculosis in an Immunocompetent 7-Year-Old Male [PDF]

, 2018
Cutaneous tuberculosis (TB) makes up a small proportion of the 10.4 million cases around the world. Although it is more commonly found in the developing world, cutaneous TB is rarely reported in the developed countries.
Austin, Dena, Galvis, Alvaro, Jaiswal, Vidyasagar, Nakamura, Craig, Pecson, Iris   +4 more
core   +2 more sources

A Trial of a Shorter Regimen for Rifampin‐Resistant Tuberculosis

New England Journal of Medicine, 2019
BACKGROUND Cohort studies in Bangladesh showed promising cure rates among patients with multidrug‐resistant tuberculosis who received existing drugs in regimens shorter than that recommended by the World Health Organization (WHO) in 2011.
A. Nunn, P. Phillips, S. Meredith, C. Chiang, F. Conradie, D. Dalai, A. Van Deun, P. Dat, N. Lan, I. Master, Tesfamarium Mebrahtu, D. Meressa, R. Moodliar, N. Ngubane, Karen Sanders, S. Squire, G. Torrea, B. Tsogt, I. Rusen   +18 more
semanticscholar   +1 more source

Aspergillosis of the CNS in a pediatric liver transplant recipient: Case report and review [PDF]

, 1991
A 2-month-old infant who had undergone orthotopic liver transplantation at the age of 2 weeks for carbamoyl phosphate synthetase deficiency developed infection of the CNS due to Aspergillus fumigatus.
Green, M, Starzl, TE, Todo, S, Tzakis, A, Wald, ER   +4 more
core   +1 more source

Treatment with isoniazid or rifampin for latent tuberculosis infection: population-based study of hepatotoxicity, completion and costs

European Respiratory Journal, 2020
Clinical trials suggest less hepatotoxicity and better adherence with 4 months rifampin (4R) versus 9 months isoniazid (9H) for treating latent tuberculosis infection (LTBI). Our objectives were to compare frequencies of severe hepatic adverse events and
L. Ronald, J. Fitzgerald, G. Bartlett-Esquilant, K. Schwartzman, A. Benedetti, J. Boivin, D. Menzies   +6 more
semanticscholar   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source