Results 31 to 40 of about 515,222 (290)
RNA polymerase I mutant affects ribosomal RNA processing and ribosomal DNA stability
RNA BiologyTranscription is a major contributor to genomic instability. The ribosomal RNA (rDNA) gene locus consists of a head-to-tail repeat of the most actively transcribed genes in the genome.
Christophe Normand +7 more
doaj +1 more source
Idiosyncratic evolution of conserved eukaryote proteins that are similar in sequence to archaeal or bacterial proteins [PDF]
, 2008 Sequence comparisons have been made between the proteins of 571 prokaryote species including 46 archaea and 525 bacteria and the set of human proteins.
Roy J. Britten
core +2 more sources
The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans [PDF]
, 2011 Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA-Argonaute complex-or miRNA-induced silencing complex (miRISC)-can regulate the translation of their targets in such diverse ways.
Bajan, Sarah +7 more
core +3 more sources
SARS-CoV-2 targets ribosomal RNA biogenesis
Cell ReportsSummary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hinders host gene expression, curbing defenses and licensing viral protein synthesis and virulence.
V. Talya Yerlici +9 more
doaj +1 more source
Heliyon, 2016 Ribosomal translocation catalyzed by EF-G hydrolyzing GTP entails multiple conformational changes of ribosome and positional changes of tRNAs and mRNA in the ribosome.
Ping Xie
doaj +1 more source
Ribosomal history reveals origins of modern protein synthesis. [PDF]
PLoS ONE, 2012 The origin and evolution of the ribosome is central to our understanding of the cellular world. Most hypotheses posit that the ribosome originated in the peptidyl transferase center of the large ribosomal subunit.
Ajith Harish, Gustavo Caetano-Anollés
doaj +1 more source
Molecules, 2011 Ribosomal RNA is the catalytic portion of ribosomes, and undergoes a variety of conformational changes during translation. Structural changes in ribosomal RNA can be facilitated by the presence of modified nucleotides. Helix 31 of bacterial 16S ribosomal
Christine S. Chow +4 more
doaj +1 more source
Hepatitis C virus 3'UTR regulates viral translation through direct interactions with the host translation machinery. [PDF]
, 2013 The 3' untranslated region (3'UTR) of hepatitis C virus (HCV) messenger RNA stimulates viral translation by an undetermined mechanism. We identified a high affinity interaction, conserved among different HCV genotypes, between the HCV 3'UTR and the host ...
Bai, Yun +2 more
core +2 more sources
Protocol for Metatranscriptomic analysis of Intestinal Microbiota [PDF]
, 2012 The objective of this publication is to provide the detailed protocol for metartancriptomisc studies of animal intestinal microbiota. The protocol describes isolation of high quality microbial community RNA from the mammalian intestinal content ...
Alvaro Hernandez +4 more
core +2 more sources
Efficient depletion of ribosomal RNA for RNA sequencing in planarians
BMC Genomics, 2019 Background The astounding regenerative abilities of planarian flatworms prompt steadily growing interest in examining their molecular foundation. Planarian regeneration was found to require hundreds of genes and is hence a complex process.
Iana V. Kim +5 more
doaj +1 more source